Results summary | View all lists in GO:BiolProc | View all genes in C01A.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
transcription, DNA-dependent | The synthesis of RNA on a template of DNA. | 2588 | 6.40 | 24 | 3.75 | 7.49e-08 |
RNA biosynthetic process | The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. | 2591 | 6.40 | 24 | 3.75 | 7.65e-08 |
regulation of transcription, DNA-dependent | Any process that modulates the frequency, rate or extent of DNA-dependent transcription. | 2510 | 6.20 | 23 | 3.71 | 1.70e-07 |
transcription from RNA polymerase II promoter | The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | 997 | 2.46 | 14 | 5.68 | 3.34e-07 |
transcription | The synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 2826 | 6.99 | 24 | 3.44 | 3.57e-07 |
regulation of transcription | Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 2702 | 6.68 | 23 | 3.44 | 5.94e-07 |
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 2802 | 6.93 | 23 | 3.32 | 1.09e-06 |
RNA metabolic process | The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. | 3263 | 8.07 | 25 | 3.10 | 1.30e-06 |
regulation of cellular metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | 3041 | 7.52 | 23 | 3.06 | 4.12e-06 |
regulation of metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. | 3184 | 7.87 | 23 | 2.92 | 8.54e-06 |
dopamine metabolic process | The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. | 25 | 0.06 | 3 | 48.54 | 3.34e-05 |
regulation of cellular process | Any process that modulates the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 5188 | 12.82 | 29 | 2.26 | 6.94e-05 |
response to oxidative stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. | 92 | 0.23 | 4 | 17.59 | 8.77e-05 |
catecholamine metabolic process | The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. | 36 | 0.09 | 3 | 33.71 | 1.01e-04 |
phenol metabolic process | The chemical reactions and pathways involving phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers. | 37 | 0.09 | 3 | 32.80 | 1.10e-04 |
cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 5.83 | 17 | 2.92 | 1.23e-04 |
cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 5.83 | 17 | 2.92 | 1.23e-04 |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 4320 | 10.68 | 25 | 2.34 | 1.25e-04 |
positive regulation of transcription | Any process that activates or increases the frequency, rate or extent of transcription. | 439 | 1.09 | 7 | 6.45 | 1.32e-04 |
keratinocyte differentiation | The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte. | 40 | 0.10 | 3 | 30.34 | 1.39e-04 |
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 450 | 1.11 | 7 | 6.29 | 1.54e-04 |
oxygen and reactive oxygen species metabolic process | The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). | 121 | 0.30 | 4 | 13.37 | 2.52e-04 |
regulation of biological process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 5630 | 13.92 | 29 | 2.08 | 2.66e-04 |
neurotransmitter metabolic process | The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. | 53 | 0.13 | 3 | 22.90 | 3.23e-04 |
regulation of transcription from RNA polymerase II promoter | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. | 701 | 1.73 | 8 | 4.62 | 4.28e-04 |
biopolymer metabolic process | The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. | 5812 | 14.37 | 29 | 2.02 | 4.39e-04 |
positive regulation of cellular metabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | 539 | 1.33 | 7 | 5.25 | 4.55e-04 |
positive regulation of metabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. | 567 | 1.40 | 7 | 4.99 | 6.12e-04 |
biological regulation | Any process that modulates the frequency, rate or extent of any biological process, quality or function. | 6089 | 15.05 | 29 | 1.93 | 8.92e-04 |
DNA alkylation | The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
DNA methylation | The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
biogenic amine metabolic process | The chemical reactions and pathways involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. | 92 | 0.23 | 3 | 13.19 | 1.61e-03 |
DNA modification | The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
positive regulation of transcription, DNA-dependent | Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription. | 368 | 0.91 | 5 | 5.50 | 2.41e-03 |
amino acid derivative metabolic process | The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. | 115 | 0.28 | 3 | 10.55 | 3.03e-03 |
regulation of neurotransmitter levels | Any process that modulates levels of neurotransmitter. | 116 | 0.29 | 3 | 10.46 | 3.11e-03 |
lymphocyte differentiation | The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. | 128 | 0.32 | 3 | 9.48 | 4.10e-03 |
mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
biopolymer methylation | The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer. | 47 | 0.12 | 2 | 17.21 | 6.14e-03 |
aromatic compound metabolic process | The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons. | 159 | 0.39 | 3 | 7.63 | 7.45e-03 |
methylation | The process by which a methyl group is covalently attached to a molecule. | 57 | 0.14 | 2 | 14.19 | 8.91e-03 |