L2L Microarray Analysis Tool
Results for C01A.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in C01A.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| RNA metabolic process | The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. | 3263 | 16.13 | 40 | 2.48 | 3.68e-07 |
| transcription, DNA-dependent | The synthesis of RNA on a template of DNA. | 2588 | 12.79 | 30 | 2.34 | 2.70e-05 |
| RNA biosynthetic process | The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. | 2591 | 12.81 | 30 | 2.34 | 2.76e-05 |
| regulation of transcription, DNA-dependent | Any process that modulates the frequency, rate or extent of DNA-dependent transcription. | 2510 | 12.41 | 29 | 2.34 | 3.85e-05 |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 4320 | 21.36 | 42 | 1.97 | 4.86e-05 |
| transcription | The synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 2826 | 13.97 | 31 | 2.22 | 5.49e-05 |
| regulation of transcription | Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 2702 | 13.36 | 30 | 2.25 | 5.80e-05 |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | 622 | 3.08 | 12 | 3.90 | 8.46e-05 |
| tRNA processing | The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. | 48 | 0.24 | 4 | 16.86 | 9.77e-05 |
| regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 2802 | 13.85 | 30 | 2.17 | 1.09e-04 |
| dopamine metabolic process | The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. | 25 | 0.12 | 3 | 24.27 | 2.56e-04 |
| regulation of cellular metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. | 3041 | 15.03 | 30 | 2.00 | 4.18e-04 |
| transcription from RNA polymerase II promoter | The synthesis of RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II-specific promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). | 997 | 4.93 | 14 | 2.84 | 5.86e-04 |
| biopolymer metabolic process | The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. | 5812 | 28.73 | 48 | 1.67 | 6.09e-04 |
| catecholamine metabolic process | The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. | 36 | 0.18 | 3 | 16.86 | 7.64e-04 |
| phenol metabolic process | The chemical reactions and pathways involving phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers. | 37 | 0.18 | 3 | 16.40 | 8.28e-04 |
| regulation of metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. | 3184 | 15.74 | 30 | 1.91 | 8.57e-04 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 11.66 | 24 | 2.06 | 9.85e-04 |
| cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 11.66 | 24 | 2.06 | 9.85e-04 |
| keratinocyte differentiation | The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte. | 40 | 0.20 | 3 | 15.17 | 1.04e-03 |
| response to oxidative stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. | 92 | 0.45 | 4 | 8.79 | 1.18e-03 |
| tRNA metabolic process | The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. | 100 | 0.49 | 4 | 8.09 | 1.61e-03 |
| neurotransmitter metabolic process | The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. | 53 | 0.26 | 3 | 11.45 | 2.35e-03 |
| regulation of cellular process | Any process that modulates the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 5188 | 25.65 | 41 | 1.60 | 3.07e-03 |
| oxygen and reactive oxygen species metabolic process | The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). | 121 | 0.60 | 4 | 6.69 | 3.21e-03 |
| DNA alkylation | The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| DNA methylation | The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| regulation of endothelial cell proliferation | Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| positive regulation of angiogenesis | Any process that activates or increases angiogenesis. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. | 77 | 0.38 | 3 | 7.88 | 6.73e-03 |
| DNA modification | The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| positive regulation of transcription | Any process that activates or increases the frequency, rate or extent of transcription. | 439 | 2.17 | 7 | 3.23 | 6.80e-03 |
| rRNA metabolic process | The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. | 78 | 0.39 | 3 | 7.78 | 6.98e-03 |
| positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 450 | 2.22 | 7 | 3.15 | 7.73e-03 |
| mRNA metabolic process | The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 453 | 2.24 | 7 | 3.13 | 8.00e-03 |
| endothelial cell proliferation | The multiplication or reproduction of endothelial cells, resulting in the rapid expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
| vasculogenesis | The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |