L2L Microarray Analysis Tool
Results for C02A.profile.u50
| Results summary | View all lists in L2L MDB | View all genes in C02A.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| serum_fibroblast_core_dn | Core group of genes consistently down-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in quiescent cells, not cell-cycle dependent) | 319 | 0.79 | 8 | 10.15 | 1.72e-06 |
| cmv_hcmv_timecourse_4hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours | 26 | 0.06 | 3 | 46.68 | 3.76e-05 |
| 5fu_resist_gastric_dn | Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines | 30 | 0.07 | 3 | 40.45 | 5.83e-05 |
| dnmt1_ko_dn | Downregulated following conditional knock-out of DNMT1 in MEFs | 38 | 0.09 | 3 | 31.94 | 1.19e-04 |
| bay_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 202 | 0.50 | 5 | 10.01 | 1.64e-04 |
| vegf_huvec_2hrs_up | Up-regulated 2 hours after VEGF treatment in human umbilical vein endothelial cells | 54 | 0.13 | 3 | 22.47 | 3.41e-04 |
| irs1_ko_adip_up | Up-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls | 159 | 0.39 | 4 | 10.18 | 7.06e-04 |
| bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 1.50 | 7 | 4.67 | 9.00e-04 |
| bay_pbmc_6hr_up | Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 475 | 1.17 | 6 | 5.11 | 1.32e-03 |
| tpa_resist_middle_dn | Downregulated by TPA at two consecutive timepoints between 2-24hrs in resistant HL-525 cells | 209 | 0.52 | 4 | 7.74 | 1.93e-03 |
| tgfb-wnt3a_mammary_dn | Down-regulated in common by both TGF-beta and Wnt3A in normal mouse mammary gland cells (top 124 genes). | 106 | 0.26 | 3 | 11.45 | 2.41e-03 |
| mkk6ee_up | Upregulated by expression of constitutively active MKK6 | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| scw_joint_react_dn | Down-regulated in rat ankle joints 16 days after intra-articular injection of Streptococcal cell wall (SCW), and 3 days after systemic injection of SCW to reactivate joint inflammation. | 231 | 0.57 | 4 | 7.01 | 2.77e-03 |
| dex_keratinocyte_4hr_up | Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 35 | 0.09 | 2 | 23.12 | 3.44e-03 |
| uvb_nhek3_c3 | Regulated by UV-B light in normal human epidermal keratinocytes, cluster 3 | 37 | 0.09 | 2 | 21.87 | 3.84e-03 |
| tpa_resist_early_dn | Downregulated by TPA at two consecutive timepoints between 15min-3hrs in resistant HL-525 cells | 140 | 0.35 | 3 | 8.67 | 5.25e-03 |
| uvc_ttd_all_up | Up-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 140 | 0.35 | 3 | 8.67 | 5.25e-03 |
| hippocampus_development_neonatal | Highly expressed in neonatal mouse hippocampus (clusters 4 and 8) | 51 | 0.13 | 2 | 15.86 | 7.19e-03 |
| il2_pbmc_48hr_up | Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 511 | 1.26 | 5 | 3.96 | 9.41e-03 |