L2L Microarray Analysis Tool
Results for C02A.profile.ud50
| Results summary | View all lists in L2L MDB | View all genes in C02A.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| serum_fibroblast_core_dn | Core group of genes consistently down-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in quiescent cells, not cell-cycle dependent) | 319 | 1.58 | 9 | 5.71 | 3.76e-05 |
| cmv_hcmv_timecourse_4hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours | 26 | 0.13 | 3 | 23.34 | 2.89e-04 |
| 5fu_resist_gastric_dn | Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines | 30 | 0.15 | 3 | 20.23 | 4.44e-04 |
| bay_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 202 | 1.00 | 6 | 6.01 | 5.60e-04 |
| dnmt1_ko_dn | Downregulated following conditional knock-out of DNMT1 in MEFs | 38 | 0.19 | 3 | 15.97 | 8.96e-04 |
| adipogenesis_hmsc_class2_up | Up-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class II) | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
| vegf_huvec_2hrs_up | Up-regulated 2 hours after VEGF treatment in human umbilical vein endothelial cells | 54 | 0.27 | 3 | 11.24 | 2.48e-03 |
| preadip_vs_fibro_dn | Downregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| tpa_resist_middle_dn | Downregulated by TPA at two consecutive timepoints between 2-24hrs in resistant HL-525 cells | 209 | 1.03 | 5 | 4.84 | 4.07e-03 |
| tpa_resist_early_dn | Downregulated by TPA at two consecutive timepoints between 15min-3hrs in resistant HL-525 cells | 140 | 0.69 | 4 | 5.78 | 5.38e-03 |
| irs1_ko_adip_up | Up-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls | 159 | 0.79 | 4 | 5.09 | 8.35e-03 |
| adip_vs_preadip_dn | Downregulated in mature murine adipocytes (7 day differentiation) vs. preadipocytes (6 hr differentiation) | 84 | 0.42 | 3 | 7.22 | 8.55e-03 |