L2L Microarray Analysis Tool
Results for C08E.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in C08E.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 1.37 | 10 | 7.30 | 1.64e-06 |
| mRNA metabolic process | The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 453 | 2.24 | 9 | 4.02 | 5.09e-04 |
| immunoglobulin mediated immune response | An immune response mediated by immunoglobulins, whether cell-bound or in solution. | 79 | 0.39 | 4 | 10.24 | 6.68e-04 |
| B cell mediated immunity | Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. | 79 | 0.39 | 4 | 10.24 | 6.68e-04 |
| DNA-dependent DNA replication | The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | 140 | 0.69 | 5 | 7.22 | 7.09e-04 |
| DNA damage response, signal transduction resulting in induction of apoptosis | A cascade of processes initiated by the detection of DNA damage and resulting in the induction of apoptosis (programmed cell death). | 36 | 0.18 | 3 | 16.86 | 7.64e-04 |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. | 347 | 1.72 | 7 | 4.08 | 1.91e-03 |
| tyrosine phosphorylation of Stat3 protein | The process of introducing a phosphoric group to a tyrosine residue of a Stat3 protein. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| negative regulation of caspase activity | Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| B cell activation | The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. | 115 | 0.57 | 4 | 7.04 | 2.67e-03 |
| lymphocyte mediated immunity | Any process involved in the carrying out of an immune response by a lymphocyte. | 116 | 0.57 | 4 | 6.97 | 2.76e-03 |
| sterol transport | The directed movement of sterols into, out of, within or between cells. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
| cholesterol transport | The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of, within or between cells. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
| RNA splicing, via transesterification reactions | Splicing of RNA via a series of two transesterification reactions. | 117 | 0.58 | 4 | 6.92 | 2.84e-03 |
| RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure. | 117 | 0.58 | 4 | 6.92 | 2.84e-03 |
| nuclear mRNA splicing, via spliceosome | The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. | 117 | 0.58 | 4 | 6.92 | 2.84e-03 |
| adaptive immune response | An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). | 119 | 0.59 | 4 | 6.80 | 3.02e-03 |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). | 119 | 0.59 | 4 | 6.80 | 3.02e-03 |
| sulfur amino acid biosynthetic process | The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| spliceosome assembly | The aggregation and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. | 59 | 0.29 | 3 | 10.28 | 3.20e-03 |
| induction of apoptosis by intracellular signals | Any process induced by intracellular signals that directly activates any of the steps required for cell death by apoptosis. | 59 | 0.29 | 3 | 10.28 | 3.20e-03 |
| leukocyte mediated immunity | Any process involved in the carrying out of an immune response by a leukocyte. | 124 | 0.61 | 4 | 6.52 | 3.50e-03 |
| regulation of DNA recombination | Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 4320 | 21.36 | 35 | 1.64 | 4.03e-03 |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | 622 | 3.08 | 9 | 2.93 | 4.34e-03 |
| positive regulation of transcription from RNA polymerase II promoter | Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter. | 226 | 1.12 | 5 | 4.47 | 5.64e-03 |
| autophagy | The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of nutrient limitation and remodeling the intracellular structure for cell differentiation. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| immune effector process | Any process of the immune system that occurs as part of an immune response. | 143 | 0.71 | 4 | 5.66 | 5.79e-03 |
| ribonucleoprotein complex biogenesis and assembly | The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together. | 239 | 1.18 | 5 | 4.23 | 7.10e-03 |
| DNA metabolic process | The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | 922 | 4.56 | 11 | 2.41 | 7.15e-03 |
| regulation of mRNA stability | Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
| regulation of DNA metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. | 80 | 0.40 | 3 | 7.59 | 7.48e-03 |
| protein-RNA complex assembly | The aggregation and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. | 154 | 0.76 | 4 | 5.25 | 7.49e-03 |
| biopolymer metabolic process | The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. | 5812 | 28.73 | 43 | 1.50 | 7.52e-03 |
| induction of apoptosis | A process that directly activates any of the steps required for cell death by apoptosis. | 341 | 1.69 | 6 | 3.56 | 7.53e-03 |
| induction of programmed cell death | A process which directly activates any of the steps required for programmed cell death. | 343 | 1.70 | 6 | 3.54 | 7.73e-03 |
| regulation of RNA stability | Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
| sulfur amino acid metabolic process | The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
| tyrosine phosphorylation of STAT protein | The process of introducing a phosphoric group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
| negative regulation of DNA metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 12 | 2.25 | 8.59e-03 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 12 | 2.24 | 9.07e-03 |
| somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |