L2L Microarray Analysis Tool
Results for D08A.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in D08A.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| adip_diff_cluster5 | Strongly upregulated at 24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 5) | 67 | 0.17 | 3 | 18.11 | 6.43e-04 |
| dox_resist_gastric_up | Upregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines | 74 | 0.18 | 3 | 16.40 | 8.59e-04 |
| oldwerner_fibro_up | Commonly upregulated in fibroblasts from Werner Syndrome and old individuals, compared to young | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| idx_tsa_up_cluster3 | Strongly up-regulated at 16-24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 3) | 136 | 0.34 | 3 | 8.92 | 4.85e-03 |
| genotoxins_all_4hrs_reg | Genes regulated in mouse lymphocytes (TK 3.7.2C) at 4 hours by all six genotoxins tested (cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide) | 45 | 0.11 | 2 | 17.98 | 5.64e-03 |
| irs1_ko_adip_up | Up-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls | 159 | 0.39 | 3 | 7.63 | 7.45e-03 |