L2L Microarray Analysis Tool
Results for G01A.profile.u50
| Results summary | View all lists in GO:BiolProc | View all genes in G01A.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| regulation of chemotaxis | Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. | 16 | 0.04 | 3 | 75.85 | 8.26e-06 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 2.85 | 13 | 4.57 | 9.04e-06 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 2.85 | 13 | 4.57 | 9.04e-06 |
| eye photoreceptor cell differentiation | The process whereby a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. | 19 | 0.05 | 3 | 63.87 | 1.42e-05 |
| eye photoreceptor cell development | Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. | 19 | 0.05 | 3 | 63.87 | 1.42e-05 |
| photoreceptor cell development | Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. | 20 | 0.05 | 3 | 60.68 | 1.67e-05 |
| photoreceptor cell differentiation | The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. | 20 | 0.05 | 3 | 60.68 | 1.67e-05 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 2.66 | 12 | 4.50 | 2.25e-05 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 2.68 | 12 | 4.47 | 2.41e-05 |
| positive regulation of epithelial cell proliferation | Any process that activates or increases the rate or extent of epithelial cell proliferation. | 25 | 0.06 | 3 | 48.54 | 3.34e-05 |
| regulation of apoptosis | Any process that modulates the occurrence or rate of cell death by apoptosis. | 785 | 1.94 | 10 | 5.15 | 3.49e-05 |
| regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 1.96 | 10 | 5.10 | 3.80e-05 |
| mesoderm development | The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. | 82 | 0.20 | 4 | 19.73 | 5.60e-05 |
| vasculogenesis | The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. | 30 | 0.07 | 3 | 40.45 | 5.83e-05 |
| eye morphogenesis | The process by which the anatomical structures of the eye are generated and organized. Morphogenesis pertains to the creation of form. | 33 | 0.08 | 3 | 36.78 | 7.80e-05 |
| anti-apoptosis | A process which directly inhibits any of the steps required for cell death by apoptosis. | 278 | 0.69 | 6 | 8.73 | 7.81e-05 |
| regulation of epithelial cell proliferation | Any process that modulates the frequency, rate or extent of epithelial cell proliferation. | 35 | 0.09 | 3 | 34.67 | 9.32e-05 |
| epithelial cell proliferation | The multiplication or reproduction of epithelial cells, resulting in the rapid expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. | 36 | 0.09 | 3 | 33.71 | 1.01e-04 |
| positive regulation of signal transduction | Any process that activates or increases the frequency, rate or extent of signal transduction. | 191 | 0.47 | 5 | 10.59 | 1.27e-04 |
| response to hypoxia | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. | 43 | 0.11 | 3 | 28.22 | 1.73e-04 |
| eye development | The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. | 48 | 0.12 | 3 | 25.28 | 2.40e-04 |
| negative regulation of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. | 345 | 0.85 | 6 | 7.04 | 2.51e-04 |
| negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 0.86 | 6 | 6.99 | 2.58e-04 |
| epithelial cell differentiation | The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. | 52 | 0.13 | 3 | 23.34 | 3.05e-04 |
| cell development | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. | 1692 | 4.18 | 13 | 3.11 | 4.06e-04 |
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of, within or between cells. | 62 | 0.15 | 3 | 19.57 | 5.12e-04 |
| lung development | The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the oesophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. | 67 | 0.17 | 3 | 18.11 | 6.43e-04 |
| response to stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). | 1358 | 3.36 | 11 | 3.28 | 7.17e-04 |
| respiratory tube development | The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. | 70 | 0.17 | 3 | 17.34 | 7.31e-04 |
| positive regulation of cellular process | Any process that activates or increases the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 1371 | 3.39 | 11 | 3.25 | 7.74e-04 |
| enzyme linked receptor protein signaling pathway | Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase. | 438 | 1.08 | 6 | 5.54 | 8.73e-04 |
| regulation of caspase activity | Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 75 | 0.19 | 3 | 16.18 | 8.93e-04 |
| amine transport | The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells. | 79 | 0.20 | 3 | 15.36 | 1.04e-03 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 5.83 | 15 | 2.57 | 1.05e-03 |
| cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 5.83 | 15 | 2.57 | 1.05e-03 |
| transmembrane receptor protein tyrosine kinase signaling pathway | The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. | 306 | 0.76 | 5 | 6.61 | 1.08e-03 |
| positive regulation of biological process | Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 1501 | 3.71 | 11 | 2.96 | 1.58e-03 |
| induction of apoptosis | A process that directly activates any of the steps required for cell death by apoptosis. | 341 | 0.84 | 5 | 5.93 | 1.73e-03 |
| induction of programmed cell death | A process which directly activates any of the steps required for programmed cell death. | 343 | 0.85 | 5 | 5.90 | 1.78e-03 |
| organic acid transport | The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of, within or between cells. | 97 | 0.24 | 3 | 12.51 | 1.87e-03 |
| carboxylic acid transport | The directed movement of carboxylic acids into, out of, within or between cells. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). | 97 | 0.24 | 3 | 12.51 | 1.87e-03 |
| sensory organ development | The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. | 101 | 0.25 | 3 | 12.02 | 2.10e-03 |
| heme metabolic process | The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. | 28 | 0.07 | 2 | 28.90 | 2.21e-03 |
| porphyrin metabolic process | The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| tetrapyrrole metabolic process | The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| morphogenesis of an epithelium | The process by which the anatomical structures of epithelia are generated and organized. Morphogenesis pertains to the creation of form. An epithelium is a sheet of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. | 113 | 0.28 | 3 | 10.74 | 2.89e-03 |
| response to external stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. | 759 | 1.88 | 7 | 3.73 | 3.17e-03 |
| positive regulation of apoptosis | Any process that activates or increases the frequency, rate or extent of cell death by apoptosis. | 396 | 0.98 | 5 | 5.11 | 3.29e-03 |
| positive regulation of programmed cell death | Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 400 | 0.99 | 5 | 5.06 | 3.44e-03 |
| tissue development | The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. | 419 | 1.04 | 5 | 4.83 | 4.18e-03 |
| regulation of catalytic activity | Any process that modulates the activity of an enzyme. | 602 | 1.49 | 6 | 4.03 | 4.23e-03 |
| response to chemical stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. | 603 | 1.49 | 6 | 4.03 | 4.26e-03 |
| regulation of I-kappaB kinase/NF-kappaB cascade | Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade. | 142 | 0.35 | 3 | 8.55 | 5.46e-03 |
| regulation of a molecular function | Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding. | 636 | 1.57 | 6 | 3.82 | 5.49e-03 |
| response to stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. | 2860 | 7.07 | 15 | 2.12 | 6.16e-03 |
| tube development | The process whose specific outcome is the progression of a tube over time, from its intial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. | 152 | 0.38 | 3 | 7.98 | 6.59e-03 |
| regulation of protein kinase activity | Any process that modulates the frequency, rate or extent of protein kinase activity. | 300 | 0.74 | 4 | 5.39 | 6.93e-03 |
| regulation of kinase activity | Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. | 305 | 0.75 | 4 | 5.31 | 7.33e-03 |
| regulation of transferase activity | Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. | 306 | 0.76 | 4 | 5.29 | 7.41e-03 |
| regulation of signal transduction | Any process that modulates the frequency, rate or extent of signal transduction. | 682 | 1.69 | 6 | 3.56 | 7.61e-03 |
| caspase activation | Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |
| pigment metabolic process | The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. | 58 | 0.14 | 2 | 13.95 | 9.21e-03 |
| positive regulation of caspase activity | Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 60 | 0.15 | 2 | 13.48 | 9.83e-03 |