Results summary | View all lists in GO:BiolProc | View all genes in G01A.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
cell cycle process | A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | 1144 | 5.66 | 21 | 3.71 | 5.27e-07 |
cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | 1307 | 6.46 | 21 | 3.25 | 4.14e-06 |
regulation of progression through cell cycle | Any process that modulates the rate or extent of progression through the cell cycle. | 875 | 4.33 | 15 | 3.47 | 4.50e-05 |
regulation of cell cycle | A cell cycle process that modulates the rate, extent or mode of the cell cycle. | 880 | 4.35 | 15 | 3.45 | 4.79e-05 |
regulation of chemotaxis | Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. | 16 | 0.08 | 3 | 37.93 | 6.45e-05 |
DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 1.37 | 8 | 5.84 | 8.55e-05 |
eye photoreceptor cell differentiation | The process whereby a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. | 19 | 0.09 | 3 | 31.94 | 1.10e-04 |
eye photoreceptor cell development | Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. | 19 | 0.09 | 3 | 31.94 | 1.10e-04 |
M phase | Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis. | 375 | 1.85 | 9 | 4.85 | 1.28e-04 |
photoreceptor cell development | Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. | 20 | 0.10 | 3 | 30.34 | 1.29e-04 |
photoreceptor cell differentiation | The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. | 20 | 0.10 | 3 | 30.34 | 1.29e-04 |
cell division | The processes resulting in the physical partitioning and separation of a cell into daughter cells. | 297 | 1.47 | 8 | 5.45 | 1.38e-04 |
cell cycle phase | A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | 474 | 2.34 | 10 | 4.27 | 1.58e-04 |
positive regulation of epithelial cell proliferation | Any process that activates or increases the rate or extent of epithelial cell proliferation. | 25 | 0.12 | 3 | 24.27 | 2.56e-04 |
spindle organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. | 28 | 0.14 | 3 | 21.67 | 3.61e-04 |
vasculogenesis | The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. | 30 | 0.15 | 3 | 20.23 | 4.44e-04 |
eye morphogenesis | The process by which the anatomical structures of the eye are generated and organized. Morphogenesis pertains to the creation of form. | 33 | 0.16 | 3 | 18.39 | 5.90e-04 |
M phase of mitotic cell cycle | Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place. | 290 | 1.43 | 7 | 4.88 | 6.82e-04 |
regulation of epithelial cell proliferation | Any process that modulates the frequency, rate or extent of epithelial cell proliferation. | 35 | 0.17 | 3 | 17.34 | 7.03e-04 |
DNA-dependent DNA replication | The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | 140 | 0.69 | 5 | 7.22 | 7.09e-04 |
epithelial cell proliferation | The multiplication or reproduction of epithelial cells, resulting in the rapid expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. | 36 | 0.18 | 3 | 16.86 | 7.64e-04 |
mesoderm development | The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. | 82 | 0.41 | 4 | 9.87 | 7.69e-04 |
DNA metabolic process | The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | 922 | 4.56 | 13 | 2.85 | 8.71e-04 |
response to hypoxia | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. | 43 | 0.21 | 3 | 14.11 | 1.29e-03 |
mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M. | 421 | 2.08 | 8 | 3.84 | 1.36e-03 |
DNA replication initiation | The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. | 44 | 0.22 | 3 | 13.79 | 1.38e-03 |
placenta development | The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
eye development | The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. | 48 | 0.24 | 3 | 12.64 | 1.77e-03 |
centrosome cycle | The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle. | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
epithelial cell differentiation | The process whereby a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. | 52 | 0.26 | 3 | 11.67 | 2.23e-03 |
cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 5.70 | 14 | 2.46 | 2.24e-03 |
positive regulation of signal transduction | Any process that activates or increases the frequency, rate or extent of signal transduction. | 191 | 0.94 | 5 | 5.30 | 2.78e-03 |
anti-apoptosis | A process which directly inhibits any of the steps required for cell death by apoptosis. | 278 | 1.37 | 6 | 4.37 | 2.84e-03 |
mitosis | Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. | 284 | 1.40 | 6 | 4.27 | 3.15e-03 |
apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 13 | 2.44 | 3.36e-03 |
microtubule organizing center organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
centrosome organization and biogenesis | A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 13 | 2.42 | 3.57e-03 |
amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of, within or between cells. | 62 | 0.31 | 3 | 9.79 | 3.68e-03 |
response to stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). | 1358 | 6.71 | 15 | 2.23 | 3.86e-03 |
regulation of cyclin-dependent protein kinase activity | Any process that modulates the frequency, rate or extent of CDK activity. | 65 | 0.32 | 3 | 9.34 | 4.20e-03 |
lung development | The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the oesophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. | 67 | 0.33 | 3 | 9.06 | 4.57e-03 |
respiratory tube development | The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. | 70 | 0.35 | 3 | 8.67 | 5.17e-03 |
aspartate family amino acid metabolic process | The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
regulation of caspase activity | Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 75 | 0.37 | 3 | 8.09 | 6.26e-03 |
regulation of apoptosis | Any process that modulates the occurrence or rate of cell death by apoptosis. | 785 | 3.88 | 10 | 2.58 | 6.53e-03 |
regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 3.92 | 10 | 2.55 | 6.98e-03 |
amine transport | The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells. | 79 | 0.39 | 3 | 7.68 | 7.22e-03 |
negative regulation of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. | 345 | 1.71 | 6 | 3.52 | 7.94e-03 |
negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 1.72 | 6 | 3.50 | 8.16e-03 |
heme metabolic process | The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. | 28 | 0.14 | 2 | 14.45 | 8.48e-03 |
porphyrin metabolic process | The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
tetrapyrrole metabolic process | The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |