Results summary | View all lists in L2L MDB | View all genes in G02A.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
dex_keratinocyte_4hr_up | Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 35 | 0.17 | 3 | 17.34 | 7.03e-04 |
adip_vs_preadip_dn | Downregulated in mature murine adipocytes (7 day differentiation) vs. preadipocytes (6 hr differentiation) | 84 | 0.42 | 4 | 9.63 | 8.41e-04 |
dixoin_pbmnc_up | Up-regulated in peripheral blood mononuclear cells of subjects with high exposure to dioxin, compared to low-exposure controls. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
bay_pbmc_2hr_up | Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 606 | 3.00 | 9 | 3.00 | 3.67e-03 |
il2_pbmc_48hr_up | Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 511 | 2.53 | 8 | 3.17 | 4.40e-03 |
aom-dss_colon_5wks_up | Up-regulated in mouse colonic mucosa after 5 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls. | 133 | 0.66 | 4 | 6.08 | 4.49e-03 |
stress_tpa_specific_up | Genes up-regulated 4 hours following TPA treatment that discriminate TPA from other stress agents | 78 | 0.39 | 3 | 7.78 | 6.98e-03 |
alk5_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 1.72 | 6 | 3.50 | 8.16e-03 |
alk5_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 1.72 | 6 | 3.50 | 8.16e-03 |
pubertal_mammary_5-6wks_dn | Down-regulated > 1.5-fold in the developing mouse mammary gland between 5 and 6 weeks of age. | 256 | 1.27 | 5 | 3.95 | 9.38e-03 |