L2L Microarray Analysis Tool
Results for H02A.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in H02A.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| cmv_all_dn | Downregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV | 213 | 0.53 | 7 | 13.29 | 1.29e-06 |
| ribavirin_rsv_dn | Up-regulation by infection of human pulmonary epithelian cells (A549) with respiratory syncytial virus (RSV) is inhibited by the anti-viral drug ribavirin | 101 | 0.25 | 5 | 20.03 | 6.00e-06 |
| cmv_24hrs_dn | Downregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV | 140 | 0.35 | 5 | 14.45 | 2.92e-05 |
| hdaci_colon_but24hrs_up | Upregulated by butyrate at 24 hrs in SW260 colon carcinoma cells | 95 | 0.23 | 4 | 17.03 | 9.93e-05 |
| idx_tsa_dn_cluster6 | Strongly down-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 6) | 48 | 0.12 | 3 | 25.28 | 2.40e-04 |
| hdaci_colon_but48hrs_up | Upregulated by butyrate at 48 hrs in SW260 colon carcinoma cells | 135 | 0.33 | 4 | 11.99 | 3.82e-04 |
| baf57_bt549_dn | Down-regulated following stable re-expression of BAF57 in Bt549 breast cancer cells that lack functional BAF57 | 554 | 1.37 | 7 | 5.11 | 5.34e-04 |
| uv-cmv_unique_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV | 164 | 0.41 | 4 | 9.87 | 7.92e-04 |
| hdaci_colon_cluster9 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 9, associated with histone hyperAc) | 78 | 0.19 | 3 | 15.56 | 1.00e-03 |
| calres_mouse_dn | Downregulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls | 79 | 0.20 | 3 | 15.36 | 1.04e-03 |
| cmv_hcmv_timecourse_24hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 24 hours | 82 | 0.20 | 3 | 14.80 | 1.16e-03 |
| reovirus_hek293_dn | Down-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney | 488 | 1.21 | 6 | 4.97 | 1.51e-03 |
| cmv-uv_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus | 207 | 0.51 | 4 | 7.82 | 1.86e-03 |
| alk5_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 0.86 | 5 | 5.83 | 1.87e-03 |
| alk5_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 0.86 | 5 | 5.83 | 1.87e-03 |
| microrna_vertebrate | Predicted MicroRNA targets conserved across human, mouse, rat, zebrafish and fugu | 214 | 0.53 | 4 | 7.56 | 2.10e-03 |
| cis_xpc_dn | Reduced expression in XPC-defective fibroblasts, compared to normal fibroblasts, following treatment with cisplatin | 363 | 0.90 | 5 | 5.57 | 2.27e-03 |
| emt_up | Up-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis) | 105 | 0.26 | 3 | 11.56 | 2.35e-03 |
| uvc_ttd_8hr_dn | Down-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 382 | 0.94 | 5 | 5.30 | 2.83e-03 |
| hdaci_colon_but_up | Upregulated by butyrate at any timepoint up to 48 hrs in SW260 colon carcinoma cells | 233 | 0.58 | 4 | 6.94 | 2.85e-03 |
| uvc_ttd_all_dn | Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 780 | 1.93 | 7 | 3.63 | 3.68e-03 |
| microrna_human | Predicted human MicroRNA targets | 2276 | 5.63 | 13 | 2.31 | 5.28e-03 |
| cmv_hcmv_timecourse_all_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints) | 839 | 2.07 | 7 | 3.38 | 5.42e-03 |
| uvc_ttd_4hr_dn | Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 641 | 1.58 | 6 | 3.79 | 5.70e-03 |
| scchn_hpvneg_dn | Down-regulated in HPV-negative squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium. | 47 | 0.12 | 2 | 17.21 | 6.14e-03 |
| microrna_mammal | Predicted MicroRNA targets conserved across human, mouse and rat | 1331 | 3.29 | 9 | 2.74 | 6.71e-03 |
| prmt5_kd_up | Up-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells | 306 | 0.76 | 4 | 5.29 | 7.41e-03 |
| pod1_ko_up | Up-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls | 508 | 1.26 | 5 | 3.98 | 9.19e-03 |
| il2_pbmc_4hr_up | Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 510 | 1.26 | 5 | 3.97 | 9.34e-03 |