L2L Microarray Analysis Tool
Results for L02B.profile.ud50
| Results summary | View all lists in L2L MDB | View all genes in L02B.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| bap_hepg2_dn | Down-regulated at least 1.4-fold following treatment of HepG2 human hepatocellular carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM. | 56 | 0.28 | 4 | 14.45 | 1.79e-04 |
| uv-4nqo_fibro_dn | Down-regulated at any timepoint by treatment of human fibroblasts with UV light or 4-NQO, but not by gamma radiation | 48 | 0.24 | 3 | 12.64 | 1.77e-03 |
| mmc_res_xenografts_up | Up-regulation is correlated with resistance of human cancer xenografts to mitomycin C | 14 | 0.07 | 2 | 28.90 | 2.14e-03 |
| dixoin_pbmnc_up | Up-regulated in peripheral blood mononuclear cells of subjects with high exposure to dioxin, compared to low-exposure controls. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| aom-dss_colon_5wks_up | Up-regulated in mouse colonic mucosa after 5 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls. | 133 | 0.66 | 4 | 6.08 | 4.49e-03 |
| cmv_hcmv_timecourse_1hr_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 1 hour | 73 | 0.36 | 3 | 8.31 | 5.81e-03 |
| 5fu_resist_gastric_dn | Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |