L2L Microarray Analysis Tool
Results for N04B.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in N04B.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| tgfb_hmvec_2hr_up | Up-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1997 | 4.94 | 21 | 4.25 | 6.19e-08 |
| tgfb_hmvec_4hr_up | Up-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1997 | 4.94 | 21 | 4.25 | 6.19e-08 |
| stemcell_neural_up | Enriched in mouse neural stem cells, compared to differentiated brain and bone marrow cells | 2805 | 6.93 | 24 | 3.46 | 3.14e-07 |
| vhl_normal_up | Upregulated in VHL-null renal carcinoma vs. normal renal cells (Fig. 2c+e) | 754 | 1.86 | 10 | 5.37 | 2.49e-05 |
| brca1_irradiated_up | Up-regulated in germline-mutant BRCA1 tumor cells compared to non-BRCA1 control tumors, following 15 Gy irradiation. | 105 | 0.26 | 4 | 15.41 | 1.46e-04 |
| stemcell_embryonic_up | Enriched in mouse embryonic stem cells, compared to differentiated brain and bone marrow cells | 1989 | 4.92 | 14 | 2.85 | 5.84e-04 |
| 5azac_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC). | 1830 | 4.52 | 13 | 2.87 | 8.28e-04 |
| reovirus_hek293_up | Up-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney | 491 | 1.21 | 6 | 4.94 | 1.56e-03 |
| cmv_hcmv_timecourse_16hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours | 93 | 0.23 | 3 | 13.05 | 1.66e-03 |
| esr_fibroblast_up | Up-regulated in the environmental stress response in human fibroblasts (regulated similarly by gamma and UV rediation and 4-NQO) | 98 | 0.24 | 3 | 12.38 | 1.93e-03 |
| tpa_resist_middle_up | Upregulated by TPA at two consecutive timepoints between 2-24hrs in resistant HL-525 cells | 100 | 0.25 | 3 | 12.14 | 2.04e-03 |
| rcc_nl_up | Upregulated in VHL-rescued renal carcinoma vs. normal renal cells (Fig. 2d+e) | 899 | 2.22 | 8 | 3.60 | 2.07e-03 |
| oldwerner_fibro_up | Commonly upregulated in fibroblasts from Werner Syndrome and old individuals, compared to young | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
| hsc_lateprogenitors_shared | Up-regulated in mouse hematopoietic late progenitors from both adult bone marrow and fetal liver (Cluster vi, Late Progenitors Shared) | 549 | 1.36 | 6 | 4.42 | 2.71e-03 |
| fsh_ovary_mcv152_dn | Down-regulated in ovarian epithelial cells (MCV152) 72 hours following FSH treatment, compared to untreated | 111 | 0.27 | 3 | 10.93 | 2.75e-03 |
| hsc_lateprogenitors_adult | Up-regulated in mouse hematopoietic late progenitors from adult bone marrow (Late Progenitors Shared + Adult) | 558 | 1.38 | 6 | 4.35 | 2.93e-03 |
| hsc_lateprogenitors_fetal | Up-regulated in mouse hematopoietic late progenitors from fetal liver (Late Progenitors Shared + Fetal) | 558 | 1.38 | 6 | 4.35 | 2.93e-03 |
| elongina_ko_up | Upregulated in MES cells from elongin-A knockout mice | 263 | 0.65 | 4 | 6.15 | 4.38e-03 |
| cmv_24hrs_up | Upregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV | 133 | 0.33 | 3 | 9.12 | 4.56e-03 |
| uvc_high_all_dn | Down-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters d1-d9) | 634 | 1.57 | 6 | 3.83 | 5.41e-03 |
| pubertal_mammary_4-5wks_dn | Down-regulated > 1.5-fold in the developing mouse mammary gland between 4 and 5 weeks of age. | 283 | 0.70 | 4 | 5.72 | 5.66e-03 |
| serum_fibroblast_core_up | Core group of genes consistently up-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in activated cells, not cell-cycle dependent) | 292 | 0.72 | 4 | 5.54 | 6.31e-03 |
| heatshock_hela_4hr_dn | Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 1829 | 4.52 | 11 | 2.43 | 6.82e-03 |
| cmv_hcmv_timecourse_all_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints) | 895 | 2.21 | 7 | 3.16 | 7.60e-03 |
| bleo_mouse_lymph_low_24hrs_dn | Down-regulated at 24 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a low dose of bleomycin | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| cited1_ko_het_dn | Down-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus heterozygotes | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| tpa_resist_early_up | Upregulated by TPA at two consecutive timepoints between 15min-3hrs in resistant HL-525 cells | 57 | 0.14 | 2 | 14.19 | 8.91e-03 |
| cmv_all_up | Upregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV | 173 | 0.43 | 3 | 7.02 | 9.38e-03 |
| brca1_overexp_up | Upregulated by induction of exogenous BRCA1 in EcR-293 cells | 328 | 0.81 | 4 | 4.93 | 9.39e-03 |