L2L Microarray Analysis Tool
Results for N06A.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in N06A.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| sterol biosynthetic process | The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 49 | 0.24 | 8 | 33.02 | 1.34e-10 |
| sterol metabolic process | The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 117 | 0.58 | 10 | 17.29 | 4.81e-10 |
| alcohol metabolic process | The chemical reactions and pathways involving alcohols, any of a class of alkyl compounds containing a hydroxyl group. | 408 | 2.02 | 14 | 6.94 | 2.75e-08 |
| steroid metabolic process | The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. | 234 | 1.16 | 11 | 9.51 | 3.57e-08 |
| steroid biosynthetic process | The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. | 99 | 0.49 | 8 | 16.35 | 4.10e-08 |
| isoprenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. | 15 | 0.07 | 4 | 53.94 | 7.81e-07 |
| cholesterol biosynthetic process | The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. | 37 | 0.18 | 5 | 27.33 | 1.13e-06 |
| cholesterol metabolic process | The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. | 106 | 0.52 | 7 | 13.36 | 1.15e-06 |
| lipid biosynthetic process | The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. | 299 | 1.48 | 10 | 6.76 | 3.23e-06 |
| ribonucleoprotein complex biogenesis and assembly | The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together. | 239 | 1.18 | 9 | 7.62 | 3.83e-06 |
| ribosome biogenesis and assembly | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. | 89 | 0.44 | 6 | 13.64 | 5.97e-06 |
| isoprenoid metabolic process | The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. | 27 | 0.13 | 4 | 29.97 | 9.57e-06 |
| lipid metabolic process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. | 877 | 4.34 | 16 | 3.69 | 1.21e-05 |
| cell cycle checkpoint | A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage. | 112 | 0.55 | 6 | 10.84 | 2.23e-05 |
| sterol transport | The directed movement of sterols into, out of, within or between cells. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 16 | 0.08 | 3 | 37.93 | 6.45e-05 |
| cholesterol transport | The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of, within or between cells. | 16 | 0.08 | 3 | 37.93 | 6.45e-05 |
| cellular lipid metabolic process | The chemical reactions and pathways involving lipids, as carried out by individual cells. | 723 | 3.57 | 13 | 3.64 | 8.81e-05 |
| M phase | Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis. | 375 | 1.85 | 9 | 4.85 | 1.28e-04 |
| biosynthetic process | The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones, as in growth and other biosynthetic processes. | 1553 | 7.68 | 20 | 2.60 | 1.43e-04 |
| DNA recombination | The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. | 158 | 0.78 | 6 | 7.68 | 1.51e-04 |
| glutamine metabolic process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. | 25 | 0.12 | 3 | 24.27 | 2.56e-04 |
| cell cycle process | A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. | 1144 | 5.66 | 16 | 2.83 | 2.59e-04 |
| regulation of cyclin-dependent protein kinase activity | Any process that modulates the frequency, rate or extent of CDK activity. | 65 | 0.32 | 4 | 12.45 | 3.18e-04 |
| fat cell differentiation | The process whereby a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. | 31 | 0.15 | 3 | 19.57 | 4.90e-04 |
| regulation of epidermal cell differentiation | Any process that modulates the frequency, rate or extent of epidermal cell differentiation. | 7 | 0.03 | 2 | 57.79 | 5.05e-04 |
| regulation of progression through cell cycle | Any process that modulates the rate or extent of progression through the cell cycle. | 875 | 4.33 | 13 | 3.01 | 5.42e-04 |
| regulation of cell cycle | A cell cycle process that modulates the rate, extent or mode of the cell cycle. | 880 | 4.35 | 13 | 2.99 | 5.71e-04 |
| mitosis | Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. | 284 | 1.40 | 7 | 4.99 | 6.04e-04 |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. | 77 | 0.38 | 4 | 10.51 | 6.06e-04 |
| rRNA metabolic process | The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. | 78 | 0.39 | 4 | 10.37 | 6.37e-04 |
| metabolic process | Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. | 9690 | 47.91 | 72 | 1.50 | 6.73e-04 |
| M phase of mitotic cell cycle | Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place. | 290 | 1.43 | 7 | 4.88 | 6.82e-04 |
| cell cycle phase | A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. | 474 | 2.34 | 9 | 3.84 | 7.01e-04 |
| mitotic checkpoint | A signal transduction-based surveillance mechanism that ensures accurate chromosome segregation by preventing entry into, passage through and exit from mitosis. Events that may be monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle and cellular morphogenesis. | 37 | 0.18 | 3 | 16.40 | 8.28e-04 |
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. | 1307 | 6.46 | 16 | 2.48 | 1.06e-03 |
| regulation of cell differentiation | Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. | 233 | 1.15 | 6 | 5.21 | 1.17e-03 |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. | 622 | 3.08 | 10 | 3.25 | 1.28e-03 |
| G2/M transition DNA damage checkpoint | A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage. | 11 | 0.05 | 2 | 36.78 | 1.31e-03 |
| G2/M transition checkpoint | Any cell cycle checkpoint that blocks entry into M phase. | 11 | 0.05 | 2 | 36.78 | 1.31e-03 |
| regulation of epidermis development | Any process that modulates the frequency, rate or extent of epidermis development. | 12 | 0.06 | 2 | 33.71 | 1.56e-03 |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 4320 | 21.36 | 36 | 1.69 | 2.31e-03 |
| cholesterol absorption | Uptake of cholesterol into the blood by absorption from the small intestine. | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
| lipid digestion | The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism. | 15 | 0.07 | 2 | 26.97 | 2.46e-03 |
| DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 1.37 | 6 | 4.38 | 2.79e-03 |
| pyrimidine ribonucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 16 | 0.08 | 2 | 25.28 | 2.80e-03 |
| transcription from RNA polymerase I promoter | The synthesis of RNA from a DNA template by RNA polymerase I (Pol I), originating at a Pol I-specific promoter. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| parturition | The process of giving birth to live offspring or eggs. | 17 | 0.08 | 2 | 23.80 | 3.16e-03 |
| glutamine family amino acid metabolic process | The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. | 60 | 0.30 | 3 | 10.11 | 3.35e-03 |
| pyrimidine ribonucleotide metabolic process | The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| cell division | The processes resulting in the physical partitioning and separation of a cell into daughter cells. | 297 | 1.47 | 6 | 4.09 | 3.91e-03 |
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. | 64 | 0.32 | 3 | 9.48 | 4.02e-03 |
| regulation of protein kinase activity | Any process that modulates the frequency, rate or extent of protein kinase activity. | 300 | 1.48 | 6 | 4.05 | 4.11e-03 |
| fructose metabolic process | The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| primary metabolic process | Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. | 8941 | 44.20 | 63 | 1.43 | 4.40e-03 |
| regulation of kinase activity | Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. | 305 | 1.51 | 6 | 3.98 | 4.44e-03 |
| regulation of transferase activity | Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. | 306 | 1.51 | 6 | 3.97 | 4.52e-03 |
| pyrimidine nucleotide biosynthetic process | The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| intestinal absorption | The processes by which nutrients are taken up from the contents of the intestine. | 21 | 0.10 | 2 | 19.26 | 4.82e-03 |
| response to DNA damage stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. | 412 | 2.04 | 7 | 3.44 | 4.87e-03 |
| regulation of cellular process | Any process that modulates the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 5188 | 25.65 | 40 | 1.56 | 5.09e-03 |
| in utero embryonic development | The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. | 70 | 0.35 | 3 | 8.67 | 5.17e-03 |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M. | 421 | 2.08 | 7 | 3.36 | 5.46e-03 |
| cellular metabolic process | The chemical reactions and pathways by which individual cells transform chemical substances. | 8889 | 43.95 | 62 | 1.41 | 5.76e-03 |
| epidermal cell differentiation | The process whereby a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. | 25 | 0.12 | 2 | 16.18 | 6.80e-03 |
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. | 79 | 0.39 | 3 | 7.68 | 7.22e-03 |
| response to endogenous stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endogenous stimulus. | 453 | 2.24 | 7 | 3.13 | 8.00e-03 |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. | 347 | 1.72 | 6 | 3.50 | 8.16e-03 |
| mRNA catabolic process, nonsense-mediated decay | The nonsense-mediated mRNA decay pathway degrades mRNAs transcribed from genes in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| digestive process | A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |