L2L Microarray Analysis Tool
Results for P02C.profile.ud50
| Results summary | View all lists in L2L MDB | View all genes in P02C.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| serum_fibroblast_cellcycle | Cell-cycle dependent genes regulated following exposure to serum in a variety of human fibroblast cell lines | 197 | 0.97 | 6 | 6.16 | 4.91e-04 |
| cmv_hcmv_timecourse_14hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours | 95 | 0.47 | 4 | 8.52 | 1.33e-03 |
| senescence_hela_dn | Down-regulated in HeLa/HPV16E6 cells 6 days following induction of senescence by repression of HPV E7 via HPV E2 and subsequent reactivation of Rb. | 341 | 1.69 | 7 | 4.15 | 1.73e-03 |
| rb_creko_up | Up-regulated at 144 hours after disruption of Rb in adult mouse fibroblasts by Cre recombination, versus GFP controls. | 344 | 1.70 | 7 | 4.12 | 1.81e-03 |
| tgfb_hmvec_2hr_dn | Down-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 353 | 1.75 | 7 | 4.01 | 2.10e-03 |
| tnfalpha_4hrs_up | Upregulated 4hrs after TNF-alpha treatment of HeLa cells | 62 | 0.31 | 3 | 9.79 | 3.68e-03 |
| cmv-uv_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus | 207 | 1.02 | 5 | 4.89 | 3.91e-03 |
| senescence_hff_dn | Down-regulated in primary human foreskin fibroblasts at replicative senescence (passage 26) compared to active replication (passage 8). | 299 | 1.48 | 6 | 4.06 | 4.04e-03 |
| as3_fibro_c5 | Downregulated moderately by sodium arsenite in fibroblasts (Cluster 5) | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| prmt5_kd_up | Up-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells | 306 | 1.51 | 6 | 3.97 | 4.52e-03 |
| vhl_normal_up | Upregulated in VHL-null renal carcinoma vs. normal renal cells (Fig. 2c+e) | 754 | 3.73 | 10 | 2.68 | 4.98e-03 |
| hdaci_colon_cur12hrs_up | Upregulated by curcumin at 12 hrs in SW260 colon carcinoma cells | 22 | 0.11 | 2 | 18.39 | 5.29e-03 |
| heat_glioblastoma_up | Up-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG). | 78 | 0.39 | 3 | 7.78 | 6.98e-03 |
| tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 6.53 | 14 | 2.14 | 7.23e-03 |
| heatshock_hela_4hr_up | Up-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 675 | 3.34 | 9 | 2.70 | 7.25e-03 |
| dac_cgi_bladder_up | Upregulated by DAC treatment in T24 bladder carcinoma cells, with 5' CpG island | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |
| tnfa_nfkb_dep_up | Up-regulated at any timepoint following TNFa treatment, only with functional NFkB | 26 | 0.13 | 2 | 15.56 | 7.34e-03 |