L2L Microarray Analysis Tool
Results for S01B.profile.u50
| Results summary | View all lists in L2L MDB | View all genes in S01B.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| lvad_heartfailure_up | Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device | 180 | 0.44 | 10 | 22.47 | 4.44e-11 |
| dex_keratinocyte_1hr_dn | Down-regulated in primary human keratinocytes at 1 hour following treatment with 0.1 microM dexamethasone | 24 | 0.06 | 5 | 84.28 | 3.77e-09 |
| bay_pbmc_48hr_dn | Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 318 | 0.79 | 6 | 7.63 | 1.62e-04 |
| hdaci_colon_cluster2 | Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 2) | 9 | 0.02 | 2 | 89.90 | 2.17e-04 |
| il2_pbmc_24hr_up | Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 503 | 1.24 | 7 | 5.63 | 3.02e-04 |
| hdaci_colon_but_up | Upregulated by butyrate at any timepoint up to 48 hrs in SW260 colon carcinoma cells | 233 | 0.58 | 5 | 8.68 | 3.17e-04 |
| il2_pbmc_48hr_dn | Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 531 | 1.31 | 7 | 5.33 | 4.16e-04 |
| ni2_mouse_up | Upregulated by nickel(II) in sensitive A/J mouse lung tissue | 65 | 0.16 | 3 | 18.67 | 5.88e-04 |
| adipogenesis_hmsc_class2_up | Up-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class II) | 15 | 0.04 | 2 | 53.94 | 6.28e-04 |
| dex_keratinocyte_4hr_dn | Down-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone | 69 | 0.17 | 3 | 17.59 | 7.01e-04 |
| hdaci_colon_tsabut_up | Upregulated by both butyrate and TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells | 79 | 0.20 | 3 | 15.36 | 1.04e-03 |
| hdaci_colon_but2hrs_up | Upregulated by butyrate at 2 hrs in SW260 colon carcinoma cells | 87 | 0.22 | 3 | 13.95 | 1.37e-03 |
| il2_pbmc_6hr_dn | Down-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2. | 530 | 1.31 | 6 | 4.58 | 2.28e-03 |
| adipogenesis_hmsc_class1_up | Up-regulated 1 day following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class I) | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| cocaine_brain_4wks_up | Up-regulated in the nucleus accumbens of mice after 4 weeks of cocaine treatment | 112 | 0.28 | 3 | 10.84 | 2.82e-03 |
| hdaci_colon_tsa_up | Upregulated by TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells | 122 | 0.30 | 3 | 9.95 | 3.58e-03 |
| senescence_hela_up | Up-regulated in HeLa/HPV16E6 cells 6 days following induction of senescence by repression of HPV E7 via HPV E2 and subsequent reactivation of Rb. | 262 | 0.65 | 4 | 6.18 | 4.32e-03 |
| vegf_huvec_30min_up | Up-regulated 30 minutes after VEGF treatment in human umbilical vein endothelial cells | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
| idx_tsa_up_cluster1 | Strongly up-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1) | 44 | 0.11 | 2 | 18.39 | 5.40e-03 |
| arthritis_mouse_common_up | Up-regulated in joint tissue from both severely arthritic HTLV-I transgenic mice and IL-1Ra knock-out mice, versus wild-type littermate controls. | 459 | 1.13 | 5 | 4.41 | 6.09e-03 |