L2L Microarray Analysis Tool
Results for S01B.profile.ud50
| Results summary | View all lists in GO:BiolProc | View all genes in S01B.profile.ud50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| circadian rhythm | The biological processes in an organism that recur with a regularity of approximately 24 hours. | 34 | 0.17 | 3 | 17.85 | 6.45e-04 |
| regulation of Ras GTPase activity | Any process that modulates the activity of a GTPase of the Ras superfamily. | 61 | 0.30 | 3 | 9.95 | 3.51e-03 |
| regulation of isotype switching | Any process that modulates the frequency, rate or extent of isotype switching. | 18 | 0.09 | 2 | 22.47 | 3.55e-03 |
| negative regulation of immune system process | Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| T-helper 2 type immune response | An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| negative regulation of immune response | Any process that stops, prevents or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. | 20 | 0.10 | 2 | 20.23 | 4.38e-03 |
| receptor-mediated endocytosis | The uptake of external materials by cells, utilizing receptors to ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. | 72 | 0.36 | 3 | 8.43 | 5.59e-03 |
| regulation of adaptive immune response | Any process that modulates the frequency, rate, or extent of an adaptive immune response. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 23 | 0.11 | 2 | 17.59 | 5.77e-03 |
| regulation of hydrolase activity | Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. | 230 | 1.14 | 5 | 4.40 | 6.07e-03 |
| B cell proliferation | The rapid expansion of a B cell population by cell division. Follows B cell activation. | 27 | 0.13 | 2 | 14.98 | 7.90e-03 |
| somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |
| isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.15 | 2 | 13.48 | 9.70e-03 |