Results summary | View all lists in GO:BiolProc | View all genes in S02B.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
regulation of Rho GTPase activity | Any process that modulates the activity of a GTPase of the Rho family. | 9 | 0.02 | 2 | 89.90 | 2.17e-04 |
negative regulation of small GTPase mediated signal transduction | Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction. | 9 | 0.02 | 2 | 89.90 | 2.17e-04 |
positive regulation of B cell proliferation | Any process that activates or increases the rate or extent of B cell proliferation. | 10 | 0.02 | 2 | 80.91 | 2.71e-04 |
negative regulation of cell-cell adhesion | Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. | 11 | 0.03 | 2 | 73.55 | 3.31e-04 |
negative regulation of B cell activation | Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. | 11 | 0.03 | 2 | 73.55 | 3.31e-04 |
erythrocyte differentiation | The process by which a myeloid precursor cell acquires specializes features of an erythrocyte. | 54 | 0.13 | 3 | 22.47 | 3.41e-04 |
regulation of cell-matrix adhesion | Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
regulation of cell-cell adhesion | Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. | 13 | 0.03 | 2 | 62.24 | 4.68e-04 |
regulation of T-helper cell differentiation | Any process that modulates the frequency, rate or extent of T-helper cell differentiation. | 13 | 0.03 | 2 | 62.24 | 4.68e-04 |
cytokine production during immune response | The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 14 | 0.03 | 2 | 57.79 | 5.45e-04 |
regulation of production of molecular mediator of immune response | Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. | 14 | 0.03 | 2 | 57.79 | 5.45e-04 |
regulation of cytokine production during immune response | Any process that modulates the frequency, rate, or extent of cytokine production during immune response. | 14 | 0.03 | 2 | 57.79 | 5.45e-04 |
regulation of B cell proliferation | Any process that modulates the frequency, rate or extent of B cell proliferation. | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
cell activation during immune response | A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
lymphocyte activation during immune response | A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
T cell activation during immune response | The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
T cell differentiation during immune response | The process whereby an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
alpha-beta T cell differentiation during immune response | The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
CD4-positive, alpha-beta T cell differentiation during immune response | The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
leukocyte activation during immune response | A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
T-helper cell differentiation | The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
regulation of isotype switching | Any process that modulates the frequency, rate or extent of isotype switching. | 18 | 0.04 | 2 | 44.95 | 9.11e-04 |
CD4-positive, alpha beta T cell differentiation | The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. | 19 | 0.05 | 2 | 42.58 | 1.02e-03 |
negative regulation of immune system process | Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
regulation of immune effector process | Any process that modulates the frequency, rate, or extent of an immune effector process. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
T-helper 2 type immune response | An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
negative regulation of immune response | Any process that stops, prevents or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
regulation of adaptive immune response | Any process that modulates the frequency, rate, or extent of an adaptive immune response. | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
regulation of T cell differentiation | Any process that modulates the frequency, rate or extent of T cell differentiation. | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
regulation of defense response | Any process that modulates the frequency, rate or extent of a defense response. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
positive regulation of locomotion | Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
regulation of inflammatory response | Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
positive regulation of B cell activation | Any process that activates or increases the frequency, rate or extent of B cell activation. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
positive regulation of cell motility | Any process that activates or increases the frequency, rate or extent of the movement of a cell. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
B cell proliferation | The rapid expansion of a B cell population by cell division. Follows B cell activation. | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
alpha-beta T cell differentiation | The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta T cell. | 28 | 0.07 | 2 | 28.90 | 2.21e-03 |
somatic recombination of immunoglobulin genes during immune response | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
somatic diversification of immunoglobulins during immune response | The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
immunoglobulin production during immune response | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
isotype switching | The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
regulation of lymphocyte differentiation | Any process that modulates the frequency, rate or extent of lymphocyte differentiation. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
somatic diversification of immune receptors via germline recombination within a single locus | The process by which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
somatic cell DNA recombination | Recombination occurring within or between DNA molecules in somatic cells. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
somatic recombination of immunoglobulin gene segments | The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
regulation of Rho protein signal transduction | Any process that modulates the frequency, rate or extent of Rho protein signal transduction. | 111 | 0.27 | 3 | 10.93 | 2.75e-03 |
regulation of response to stimulus | Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. | 32 | 0.08 | 2 | 25.28 | 2.88e-03 |
somatic diversification of immune receptors | The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
circadian rhythm | The biological processes in an organism that recur with a regularity of approximately 24 hours. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
somatic diversification of immunoglobulins | The somatic process by means of which sequence diversity of immunoglobulins is generated. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
negative regulation of lymphocyte activation | Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation. | 34 | 0.08 | 2 | 23.80 | 3.25e-03 |
alpha-beta T cell activation | The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. | 36 | 0.09 | 2 | 22.47 | 3.64e-03 |
negative regulation of cell adhesion | Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion. | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
regulation of B cell activation | Any process that modulates the frequency, rate or extent of B cell activation. | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
regulation of cytokine production | Any process that modulates the frequency, rate, or extent of production of a cytokine. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
immunoglobulin production | The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
cell-matrix adhesion | The binding of a cell to the extracellular matrix via adhesion molecules. | 132 | 0.33 | 3 | 9.19 | 4.46e-03 |
cell-substrate adhesion | The attachment of a cell to the underlying substrate via adhesion molecules. | 135 | 0.33 | 3 | 8.99 | 4.75e-03 |
negative regulation of transcription | Any process that stops, prevents or reduces the frequency, rate or extent of transcription. | 439 | 1.09 | 5 | 4.61 | 5.07e-03 |
positive regulation of mononuclear cell proliferation | Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
positive regulation of lymphocyte proliferation | Any process that activates or increases the rate or extent of lymphocyte proliferation. | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
myeloid cell differentiation | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. | 142 | 0.35 | 3 | 8.55 | 5.46e-03 |
negative regulation of multicellular organismal process | Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. | 46 | 0.11 | 2 | 17.59 | 5.88e-03 |
Rho protein signal transduction | A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. | 150 | 0.37 | 3 | 8.09 | 6.36e-03 |
production of molecular mediator of immune response | The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels. | 51 | 0.13 | 2 | 15.86 | 7.19e-03 |
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 478 | 1.18 | 5 | 4.23 | 7.19e-03 |
epidermis development | The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of a plant or animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. | 158 | 0.39 | 3 | 7.68 | 7.33e-03 |
regulation of transcription from RNA polymerase II promoter | Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. | 701 | 1.73 | 6 | 3.46 | 8.64e-03 |
B cell differentiation | The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a B cell. | 57 | 0.14 | 2 | 14.19 | 8.91e-03 |