L2L L2L Microarray Analysis Tool

Results for A01AC.profile.ud50

Results summary View all lists in GO:BiolProc View all genes in A01AC.profile.ud50
List Name Description Total
probes		 Expected
matches		 Actual
matches		 Fold
Enrichment		 Binomial
p-value
positive regulation of B cell proliferation Any process that activates or increases the rate or extent of B cell proliferation. 10 0.05 2 40.45 1.07e-03
purine nucleoside metabolic process The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). 10 0.05 2 40.45 1.07e-03
purine ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. 10 0.05 2 40.45 1.07e-03
ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. 12 0.06 2 33.71 1.56e-03
positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. 1371 6.78 16 2.36 1.71e-03
negative regulation of transcription Any process that stops, prevents or reduces the frequency, rate or extent of transcription. 439 2.17 8 3.69 1.76e-03
sensory perception of pain The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. 15 0.07 2 26.97 2.46e-03
regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction. 682 3.37 10 2.97 2.48e-03
regulation of B cell proliferation Any process that modulates the frequency, rate or extent of B cell proliferation. 16 0.08 2 25.28 2.80e-03
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. 478 2.36 8 3.39 2.96e-03
regulation of isotype switching Any process that modulates the frequency, rate or extent of isotype switching. 18 0.09 2 22.47 3.55e-03
positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. 1501 7.42 16 2.16 4.08e-03
RNA modification The covalent alteration of one or more nucleotides within RNA, resulting in a change in the properties of the RNA. 23 0.11 2 17.59 5.77e-03
negative regulation of cellular metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. 536 2.65 8 3.02 5.81e-03
regulation of JNK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade. 25 0.12 2 16.18 6.80e-03
focal adhesion formation Establishment and maturation of focal adhesions, complexes of intracellular signaling and structural proteins which provide a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. 25 0.12 2 16.18 6.80e-03
positive regulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. 25 0.12 2 16.18 6.80e-03
positive regulation of cell proliferation Any process that activates or increases the rate or extent of cell proliferation. 338 1.67 6 3.59 7.22e-03
B cell proliferation The rapid expansion of a B cell population by cell division. Follows B cell activation. 27 0.13 2 14.98 7.90e-03
mRNA catabolic process, nonsense-mediated decay The nonsense-mediated mRNA decay pathway degrades mRNAs transcribed from genes in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. 30 0.15 2 13.48 9.70e-03
somatic recombination of immunoglobulin genes during immune response The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. 30 0.15 2 13.48 9.70e-03
somatic diversification of immunoglobulins during immune response The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. 30 0.15 2 13.48 9.70e-03
immunoglobulin production during immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. 30 0.15 2 13.48 9.70e-03
isotype switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. 30 0.15 2 13.48 9.70e-03

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