L2L Microarray Analysis Tool
Results for C10AA.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in C10AA.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| cmv_hcmv_timecourse_6hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 6 hours | 95 | 0.23 | 5 | 21.29 | 4.44e-06 |
| il6_scar_fibro_dn | Downregulated following IL-6 treatment in hypertrophic scar fibroblasts | 22 | 0.05 | 3 | 55.16 | 2.25e-05 |
| cantharidin_up | Upregulated in HL-60 promyeloid leukemic cells after treatment with the cytotoxic drug cantharidin | 27 | 0.07 | 3 | 44.95 | 4.23e-05 |
| o6bg_resist_medulloblastoma_up | Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED) | 46 | 0.11 | 3 | 26.38 | 2.12e-04 |
| dnmt1_ko_up | Upregulated following conditional knock-out of DNMT1 in MEFs | 117 | 0.29 | 4 | 13.83 | 2.22e-04 |
| uvb_scc_dn | Downregulated by UV-B light in squamous cell carinoma cells | 219 | 0.54 | 5 | 9.24 | 2.39e-04 |
| p21_early_dn | Down-regulated at early timepoints (4-8 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 16 | 0.04 | 2 | 50.57 | 7.17e-04 |
| pubertal_mammary_4-5wks_dn | Down-regulated > 1.5-fold in the developing mouse mammary gland between 4 and 5 weeks of age. | 283 | 0.70 | 5 | 7.15 | 7.63e-04 |
| gh_igf_chondrocytes_up | Up-regulated in cultured human chondrocytes by both GH and IGF-1 | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
| preadip_vs_fibro_dn | Downregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
| scar_fibro_dn | Downregulated in hypertrophic scar fibroblasts, compared to normal skin fibroblasts | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
| p21_p53_any_dn | Down-regulated at any timepoint (4-24 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent | 77 | 0.19 | 3 | 15.76 | 9.64e-04 |
| brca1ko_mef_up | Up-regulated in mouse embryonic fibroblasts following targeted deletion of BRCA1 (exon 11) compared to wild-type MEFs | 19 | 0.05 | 2 | 42.58 | 1.02e-03 |
| ad12_48hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 48 hours post-infection | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
| p21_p53_early_dn | Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent | 23 | 0.06 | 2 | 35.18 | 1.49e-03 |
| uvc_high_d3_dn | Progressively down-regulated through 12 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d3) | 90 | 0.22 | 3 | 13.48 | 1.51e-03 |
| ad12_24hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 24 hours post-infection | 24 | 0.06 | 2 | 33.71 | 1.63e-03 |
| ad12_32hrs_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 32 hours post-infection | 27 | 0.07 | 2 | 29.97 | 2.06e-03 |
| idx_tsa_dn_cluster3 | Strongly down-regulated at 8-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 3) | 108 | 0.27 | 3 | 11.24 | 2.54e-03 |
| vegf_huvec_30min_up | Up-regulated 30 minutes after VEGF treatment in human umbilical vein endothelial cells | 41 | 0.10 | 2 | 19.73 | 4.70e-03 |
| ad12_any_dn | Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection | 42 | 0.10 | 2 | 19.26 | 4.93e-03 |
| prmt5_kd_dn | Down-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells | 45 | 0.11 | 2 | 17.98 | 5.64e-03 |
| uvb_nhek4_6hrs_up | Upregulated at 6 hours by UV-B light in normal human epidermal keratinocytes | 49 | 0.12 | 2 | 16.51 | 6.65e-03 |
| p21_any_dn | Down-regulated at any timepoint (4-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells | 50 | 0.12 | 2 | 16.18 | 6.92e-03 |
| uvc_high_d9_dn | Progressively down-regulated through 24 hrs following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d9) | 53 | 0.13 | 2 | 15.27 | 7.74e-03 |
| uv-cmv_unique_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV | 164 | 0.41 | 3 | 7.40 | 8.11e-03 |
| adipogenesis_hmsc_class8_dn | Down-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class VIII) | 59 | 0.15 | 2 | 13.71 | 9.52e-03 |
| heatshock_hela_2hr_up | Up-regulated at 2 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05). | 177 | 0.44 | 3 | 6.86 | 9.97e-03 |