Results summary | View all lists in GO:MoleFunc | View all genes in G01AF.profile.d50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
structure-specific DNA binding | Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding. | 142 | 0.35 | 6 | 17.09 | 1.75e-06 |
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 25 | 0.06 | 3 | 48.54 | 3.34e-05 |
double-stranded DNA binding | Interacting selectively with double-stranded DNA. | 88 | 0.22 | 4 | 18.39 | 7.38e-05 |
cyclin-dependent protein kinase regulator activity | Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. | 7 | 0.02 | 2 | 115.58 | 1.27e-04 |
ribonuclease H activity | Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. | 8 | 0.02 | 2 | 101.14 | 1.69e-04 |
MutLalpha complex binding | Interacting selectively with the mismatch repair complex MutLalpha. | 9 | 0.02 | 2 | 89.90 | 2.17e-04 |
mismatch repair complex binding | Interacting selectively with a mismatch repair complex. | 11 | 0.03 | 2 | 73.55 | 3.31e-04 |
damaged DNA binding | Interacting selectively with damaged DNA. | 56 | 0.14 | 3 | 21.67 | 3.80e-04 |
exodeoxyribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
exodeoxyribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
exonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. | 61 | 0.15 | 3 | 19.90 | 4.88e-04 |
ribonuclease activity | Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. | 67 | 0.17 | 3 | 18.11 | 6.43e-04 |
single-stranded DNA binding | Interacting selectively with single-stranded DNA. | 72 | 0.18 | 3 | 16.86 | 7.93e-04 |
ADP binding | Interacting selectively with ADP, adenosine 5'-diphosphate. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
DNA N-glycosylase activity | Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. | 19 | 0.05 | 2 | 42.58 | 1.02e-03 |
endodeoxyribonuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. | 22 | 0.05 | 2 | 36.78 | 1.37e-03 |
hydrolase activity, hydrolyzing N-glycosyl compounds | 22 | 0.05 | 2 | 36.78 | 1.37e-03 | |
mismatched DNA binding | Interacting selectively with double-stranded DNA containing one or more mismatches. | 26 | 0.06 | 2 | 31.12 | 1.91e-03 |
endoribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
RNA binding | Interacting selectively with an RNA molecule or a portion thereof. | 982 | 2.43 | 8 | 3.30 | 3.52e-03 |
deoxyribonuclease activity | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
endoribonuclease activity | Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. | 48 | 0.12 | 2 | 16.86 | 6.39e-03 |
nucleic acid binding | Interacting selectively with any nucleic acid. | 3764 | 9.30 | 18 | 1.93 | 7.26e-03 |
nuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids. | 161 | 0.40 | 3 | 7.54 | 7.71e-03 |
nucleotide binding | Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety. | 2671 | 6.60 | 14 | 2.12 | 7.99e-03 |
DNA helicase activity | Catalysis of the hydrolysis of an NTP or dNTP to unwind the DNA helix. | 55 | 0.14 | 2 | 14.71 | 8.32e-03 |