L2L Microarray Analysis Tool
Results for G01AF.profile.u50
| Results summary | View all lists in GO:BiolProc | View all genes in G01AF.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. | 319 | 0.79 | 7 | 8.88 | 1.80e-05 |
| response to stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). | 1358 | 3.36 | 13 | 3.87 | 4.87e-05 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 2.66 | 11 | 4.13 | 1.04e-04 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 2.68 | 11 | 4.10 | 1.11e-04 |
| response to hypoxia | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. | 43 | 0.11 | 3 | 28.22 | 1.73e-04 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 2.85 | 11 | 3.86 | 1.84e-04 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 2.85 | 11 | 3.86 | 1.84e-04 |
| response to stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. | 2860 | 7.07 | 18 | 2.55 | 3.97e-04 |
| sequestering of calcium ion | The process of binding or confining calcium ions such that they are separated from other components of a biological system. | 14 | 0.03 | 2 | 57.79 | 5.45e-04 |
| anti-apoptosis | A process which directly inhibits any of the steps required for cell death by apoptosis. | 278 | 0.69 | 5 | 7.28 | 7.05e-04 |
| response to biotic stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. | 282 | 0.70 | 5 | 7.17 | 7.51e-04 |
| regulation of apoptosis | Any process that modulates the occurrence or rate of cell death by apoptosis. | 785 | 1.94 | 8 | 4.12 | 8.88e-04 |
| regulation of caspase activity | Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 75 | 0.19 | 3 | 16.18 | 8.93e-04 |
| regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 1.96 | 8 | 4.08 | 9.47e-04 |
| sequestering of metal ion | The process of binding or confining metal ions such that they are separated from other components of a biological system. | 19 | 0.05 | 2 | 42.58 | 1.02e-03 |
| ER-nuclear signaling pathway | Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. | 20 | 0.05 | 2 | 40.45 | 1.13e-03 |
| response to unfolded protein | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. | 83 | 0.21 | 3 | 14.62 | 1.20e-03 |
| response to protein stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. | 83 | 0.21 | 3 | 14.62 | 1.20e-03 |
| glutamine metabolic process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. | 25 | 0.06 | 2 | 32.36 | 1.77e-03 |
| amino acid metabolic process | The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents. | 344 | 0.85 | 5 | 5.88 | 1.80e-03 |
| acute inflammatory response | Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. | 96 | 0.24 | 3 | 12.64 | 1.82e-03 |
| negative regulation of apoptosis | Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. | 345 | 0.85 | 5 | 5.86 | 1.82e-03 |
| negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 0.86 | 5 | 5.83 | 1.87e-03 |
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. | 97 | 0.24 | 3 | 12.51 | 1.87e-03 |
| amine metabolic process | The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. | 538 | 1.33 | 6 | 4.51 | 2.45e-03 |
| regulation of hydrolase activity | Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. | 230 | 0.57 | 4 | 7.04 | 2.72e-03 |
| nitrogen compound metabolic process | The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. | 580 | 1.43 | 6 | 4.18 | 3.54e-03 |
| complement activation, classical pathway | Processes involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. | 36 | 0.09 | 2 | 22.47 | 3.64e-03 |
| alcohol metabolic process | The chemical reactions and pathways involving alcohols, any of a class of alkyl compounds containing a hydroxyl group. | 408 | 1.01 | 5 | 4.96 | 3.73e-03 |
| cell development | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. | 1692 | 4.18 | 11 | 2.63 | 3.90e-03 |
| humoral immune response mediated by circulating immunoglobulin | An immune response dependent upon secreted immunoglobulin. | 38 | 0.09 | 2 | 21.29 | 4.05e-03 |
| regulation of catalytic activity | Any process that modulates the activity of an enzyme. | 602 | 1.49 | 6 | 4.03 | 4.23e-03 |
| cofactor biosynthetic process | The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein. | 134 | 0.33 | 3 | 9.06 | 4.65e-03 |
| amino acid and derivative metabolic process | The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids. | 440 | 1.09 | 5 | 4.60 | 5.12e-03 |
| activation of plasma proteins during acute inflammatory response | Any process activating plasma proteins via proteolysis during an acute inflammatory response. | 44 | 0.11 | 2 | 18.39 | 5.40e-03 |
| complement activation | Processes involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. | 44 | 0.11 | 2 | 18.39 | 5.40e-03 |
| regulation of a molecular function | Any process that modulates the frequency, rate or extent of molecular functions. Molecular functions are elemental biological activities occurring at the molecular level, such as catalysis or binding. | 636 | 1.57 | 6 | 3.82 | 5.49e-03 |
| biosynthetic process | The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones, as in growth and other biosynthetic processes. | 1553 | 3.84 | 10 | 2.60 | 6.14e-03 |
| insulin receptor signaling pathway | The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. | 51 | 0.13 | 2 | 15.86 | 7.19e-03 |
| carboxylic acid metabolic process | The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). | 679 | 1.68 | 6 | 3.57 | 7.46e-03 |
| organic acid metabolic process | The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. | 681 | 1.68 | 6 | 3.56 | 7.56e-03 |
| caspase activation | Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |
| tRNA aminoacylation for protein translation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis. | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| amino acid activation | The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| tRNA aminoacylation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| maintenance of localization | The processes by which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. | 56 | 0.14 | 2 | 14.45 | 8.61e-03 |
| glutamine family amino acid metabolic process | The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. | 60 | 0.15 | 2 | 13.48 | 9.83e-03 |
| positive regulation of caspase activity | Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis. | 60 | 0.15 | 2 | 13.48 | 9.83e-03 |