L2L Microarray Analysis Tool
Results for G03CA.profile.d50
| Results summary | View all lists in L2L MDB | View all genes in G03CA.profile.d50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| alk5_hmvec_2hr_dn | Down-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 202 | 0.50 | 5 | 10.01 | 1.64e-04 |
| alk5_hmvec_4hr_dn | Down-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 202 | 0.50 | 5 | 10.01 | 1.64e-04 |
| uvb_scc_dn | Downregulated by UV-B light in squamous cell carinoma cells | 219 | 0.54 | 5 | 9.24 | 2.39e-04 |
| brca_prognosis_pos | Genes whose expression is consistently positively correlated with breast cancer outcomes - higher expression is associated with good prognosis | 57 | 0.14 | 3 | 21.29 | 4.00e-04 |
| uvc_ttd_all_up | Up-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 140 | 0.35 | 4 | 11.56 | 4.38e-04 |
| tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 3.27 | 11 | 3.37 | 5.74e-04 |
| tsa_hepg2_up | Up-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 500 nM trichostatin A (TSA). | 936 | 2.31 | 9 | 3.89 | 6.55e-04 |
| cmv_hcmv_timecourse_14hrs_dn | Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours | 95 | 0.23 | 3 | 12.77 | 1.76e-03 |
| hsc_hscandprogenitors_fetal | Up-regulated in mouse hematopoietic stem cells and progenitors from fetal liver (HSC and Progenitors Shared) | 717 | 1.77 | 7 | 3.95 | 2.32e-03 |
| hsc_hscandprogenitors_shared | Up-regulated in mouse hematopoietic stem cells and progenitors from both adult bone marrow and fetal liver (Cluster iii, HSC and Progenitors Shared) | 717 | 1.77 | 7 | 3.95 | 2.32e-03 |
| uvc_ttd_4hr_up | Up-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC | 105 | 0.26 | 3 | 11.56 | 2.35e-03 |
| hsc_hscandprogenitors_adult | Up-regulated in mouse hematopoietic stem cells and progenitors from adult bone marrow (HSC and Progenitors Shared + Adult) | 724 | 1.79 | 7 | 3.91 | 2.45e-03 |
| uvb_nhek1_dn | Downregulated by UV-B light in normal human epidermal keratinocytes | 542 | 1.34 | 6 | 4.48 | 2.54e-03 |
| cmv_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV) | 109 | 0.27 | 3 | 11.13 | 2.61e-03 |
| bap_mcf7_dn | Down-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM. | 135 | 0.33 | 3 | 8.99 | 4.75e-03 |
| 5fu_resist_gastric_up | Upregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines | 42 | 0.10 | 2 | 19.26 | 4.93e-03 |
| cited1_ko_het_up | Up-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus heterozygotes | 43 | 0.11 | 2 | 18.82 | 5.16e-03 |
| brca_er_pos | Genes whose expression is consistently positively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-positive tumors | 842 | 2.08 | 7 | 3.36 | 5.53e-03 |
| 17aag_ovca_up | Up-regulated 24 hours following treatment of human ovarian cancer cells (A2780) with the HSP90 inhibitor 17AAG (60 nM) | 53 | 0.13 | 2 | 15.27 | 7.74e-03 |
| cmv_uv-cmv_common_hcmv_6hrs_dn | Down-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV | 54 | 0.13 | 2 | 14.98 | 8.03e-03 |