L2L L2L Microarray Analysis Tool

Results for G03CA.profile.u50

Results summary View all lists in L2L MDB View all genes in G03CA.profile.u50
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
alk5_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 0.86 9 10.49 2.95e-07
alk5_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). 347 0.86 9 10.49 2.95e-07
alk1_hmvec_2hr_up Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 1.47 9 6.14 2.23e-05
alk1_hmvec_4hr_up Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). 593 1.47 9 6.14 2.23e-05
5azac_hepg2_dn Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC). 1830 4.52 14 3.09 2.59e-04
bay_pbmc_30min_up up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. 82 0.20 3 14.80 1.16e-03
hypoxia_rcc_novhl_up Upregulated by hypoxia in VHL-null renal carcinoma cells (Fig. 4h+i) 88 0.22 3 13.79 1.42e-03
cmv_hcmv_timecourse_16hrs_up Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours 93 0.23 3 13.05 1.66e-03
tgfb_hmvec_4hr_dn Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. 1321 3.27 10 3.06 2.00e-03
cocaine_brain_5d_up Up-regulated in the nucleus accumbens of mice after 5 days of cocaine treatment 113 0.28 3 10.74 2.89e-03
cmv_24hrs_up Upregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV 133 0.33 3 9.12 4.56e-03
calres_presenillin_ko_hippocampus_up Up-regulated by calorie restriction in the hippocampus of 8 month-old presenillin-1 and -2 conditional double knock-out mice, compared to normal-diet controls. 137 0.34 3 8.86 4.95e-03
diab_neph_dn Downregulated in the glomeruli of cadaver kidneys from patients with diabetic nephropathy, compared to normal controls 829 2.05 7 3.42 5.09e-03
5azac-tsa_hepg2_dn Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA). 2343 5.79 13 2.24 6.65e-03
cmv_all_up Upregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV 173 0.43 3 7.02 9.38e-03

Raw data (tab-delimited .txt)