Results summary | View all lists in L2L MDB | View all genes in G03CA.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
alk5_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 0.86 | 9 | 10.49 | 2.95e-07 |
alk5_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC). | 347 | 0.86 | 9 | 10.49 | 2.95e-07 |
alk1_hmvec_2hr_up | Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 1.47 | 9 | 6.14 | 2.23e-05 |
alk1_hmvec_4hr_up | Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC). | 593 | 1.47 | 9 | 6.14 | 2.23e-05 |
5azac_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC). | 1830 | 4.52 | 14 | 3.09 | 2.59e-04 |
bay_pbmc_30min_up | up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist. | 82 | 0.20 | 3 | 14.80 | 1.16e-03 |
hypoxia_rcc_novhl_up | Upregulated by hypoxia in VHL-null renal carcinoma cells (Fig. 4h+i) | 88 | 0.22 | 3 | 13.79 | 1.42e-03 |
cmv_hcmv_timecourse_16hrs_up | Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours | 93 | 0.23 | 3 | 13.05 | 1.66e-03 |
tgfb_hmvec_4hr_dn | Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta. | 1321 | 3.27 | 10 | 3.06 | 2.00e-03 |
cocaine_brain_5d_up | Up-regulated in the nucleus accumbens of mice after 5 days of cocaine treatment | 113 | 0.28 | 3 | 10.74 | 2.89e-03 |
cmv_24hrs_up | Upregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV | 133 | 0.33 | 3 | 9.12 | 4.56e-03 |
calres_presenillin_ko_hippocampus_up | Up-regulated by calorie restriction in the hippocampus of 8 month-old presenillin-1 and -2 conditional double knock-out mice, compared to normal-diet controls. | 137 | 0.34 | 3 | 8.86 | 4.95e-03 |
diab_neph_dn | Downregulated in the glomeruli of cadaver kidneys from patients with diabetic nephropathy, compared to normal controls | 829 | 2.05 | 7 | 3.42 | 5.09e-03 |
5azac-tsa_hepg2_dn | Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA). | 2343 | 5.79 | 13 | 2.24 | 6.65e-03 |
cmv_all_up | Upregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV | 173 | 0.43 | 3 | 7.02 | 9.38e-03 |