#list name	reference	description	total probes	expected	actual	enrichment	bin prob	analysis_name
17aag_ovca_dn	17409432	Down-regulated 24 hours following treatment of human ovarian cancer cells (A2780) with the HSP90 inhibitor 17AAG (60 nM)	129	0.637761408018985	0	0	1	J01AA.profile.ud50
17aag_ovca_up	17409432	Up-regulated 24 hours following treatment of human ovarian cancer cells (A2780) with the HSP90 inhibitor 17AAG (60 nM)	53	0.262026004845009	0	0	1	J01AA.profile.ud50
3ab_gamma_dn	12379459	Downregulated synergystically by gamma-irradiation and 3-aminobenzamine (PARP inhibitor)	20	0.098877737677362	0	0	1	J01AA.profile.ud50
3ab_gamma_up	12379459	Upregulated synergystically by gamma-irradiation and 3-aminobenzamine (PARP inhibitor)	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
4nqo_esr_old_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of fibroblasts from elderly donors with 4-nitroquinoline-1-oxide (4NQO)	21	0.10382162456123	0	0	1	J01AA.profile.ud50
4nqo_esr_ws_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of Werner syndrome fibroblasts with 4-nitroquinoline-1-oxide (4NQO)	59	0.291689326148218	0	0	1	J01AA.profile.ud50
4nqo-gamma_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with gamma radiation or 4-NQO, but not by UV light	18	0.0889899639096258	1	11.2372222222222	0.0853471364577099	J01AA.profile.ud50
4nqo-gamma_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with gamma radiation or 4-NQO, but not by UV light	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
4nqo_unique_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with 4-nitroquinoline-1-oxide (4NQO), but not UV or gamma radiation	25	0.123597172096702	0	0	1	J01AA.profile.ud50
4nqo_unique_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with 4-nitroquinoline-1-oxide (4NQO), but not by UV or gamma radiation	38	0.187867701586988	0	0	1	J01AA.profile.ud50
5azac_hepg2_dn	16854234	Down-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC).	1830	9.04731299747862	10	1.10530054644809	0.418840448860221	J01AA.profile.ud50
5azac_hepg2_up	16854234	Up-regulated in human hepatoma cells (HepG2) following 48 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC).	1630	8.058535620705	9	1.1168282208589	0.415642846693562	J01AA.profile.ud50
5azac-tsa_hepg2_dn	16854234	Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA).	2343	11.583526968903	16	1.38127187366624	0.12648964635112	J01AA.profile.ud50
5azac-tsa_hepg2_up	16854234	Up-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 2.5 microM 5-aza-2-deoxycytidine (5azaC) and 24 hrs treatment with both 5azaC and 500 nM trichostatin A (TSA).	1966	9.71968161368468	8	0.823072227873855	0.754119823575569	J01AA.profile.ud50
5fu_resist_gastric_dn	14734480	Downregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines	30	0.148316606516043	0	0	1	J01AA.profile.ud50
5fu_resist_gastric_up	14734480	Upregulated in gastric cancer cell lines reistant to 5-fluorouracil, compared to parent chemosensitive lines	42	0.20764324912246	0	0	1	J01AA.profile.ud50
5fu_res_xenografts_dn	11809704	Down-regulation is correlated with resistance of human cancer xenografts to 5-fluorouracil (5FU)	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
5fu_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to 5-fluorouracil (5FU)	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
acnu_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to ACNU	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
ad12_12hrs_dn	15681441	Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 12 hours post-infection	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
ad12_12hrs_up	15681441	Up-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 12 hours post-infection	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
ad12_24hrs_dn	15681441	Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 24 hours post-infection	24	0.118653285212834	0	0	1	J01AA.profile.ud50
ad12_32hrs_dn	15681441	Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 32 hours post-infection	27	0.133484945864439	0	0	1	J01AA.profile.ud50
ad12_48hrs_dn	15681441	Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at 48 hours post-infection	21	0.10382162456123	0	0	1	J01AA.profile.ud50
ad12_any_dn	15681441	Down-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection	42	0.20764324912246	0	0	1	J01AA.profile.ud50
ad12_any_up	15681441	Up-regulated 2-fold in HeLa cells by Adenovirus type 12 (Ad12) at any timepoint to 48 hrs hours post-infection	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
adip_diff_cluster1	12137940	Progressively downregulated over 24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 1)	96	0.474613140851337	0	0	1	J01AA.profile.ud50
adip_diff_cluster2	12137940	Strongly upregulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 2)	64	0.316408760567558	1	3.16046875	0.2718101578629	J01AA.profile.ud50
adip_diff_cluster3	12137940	Strongly upregulated at 8 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 3)	68	0.336184308103031	0	0	1	J01AA.profile.ud50
adip_diff_cluster4	12137940	Strongly upregulated at 16 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 4)	56	0.276857665496613	0	0	1	J01AA.profile.ud50
adip_diff_cluster5	12137940	Strongly upregulated at 24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 5)	67	0.331240421219163	0	0	1	J01AA.profile.ud50
adip_diff_up	12732648	Upregulated in mature adipocytes following diffferentiation from 3T3-L1 fibroblasts	123	0.608098086715776	0	0	1	J01AA.profile.ud50
adip_human_dn	15051823	Down-regulated in primary human adipocytes, versus preadipocytes	52	0.257082117961141	1	3.88980769230769	0.227188188948653	J01AA.profile.ud50
adip_human_up	15051823	Up-regulated in primary human adipocytes, versus preadipocytes	94	0.464725367083601	0	0	1	J01AA.profile.ud50
adipocyte_brca_dn	14508521	Downregulated in breast cancer cells (MCF-7) treated with adipocyte-conditioned growth media	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
adipocyte_brca_up	14508521	Upregulated in breast cancer cells (MCF-7) treated with adipocyte-conditioned growth media	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
adipocyte_pparg_up	11981038	Adipocyte genes induced by both PPARgamma and rosiglitazone	23	0.113709398328966	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class1_up	12646203	Up-regulated 1 day following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class I)	31	0.153260493399911	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class2_up	12646203	Up-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class II)	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class3_up	12646203	Up-regulated 3-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class III)	109	0.538883670341623	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class4_up	12646203	Up-regulated 14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class IV)	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class5_up	12646203	Up-regulated 9 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class V)	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class7_dn	12646203	Down-regulated 1 day following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class VII)	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
adipogenesis_hmsc_class8_dn	12646203	Down-regulated 1-14 days following the differentiation of human bone marrow mesenchymal stem cells (hMSC) into adipocytes, versus untreated hMSC cells (Class VIII)	59	0.291689326148218	0	0	1	J01AA.profile.ud50
adip_vs_fibro_dn	12021175	Downregulated following 7-day differentiation of murine 3T3-L1 fibroblasts into adipocytes	64	0.316408760567558	1	3.16046875	0.2718101578629	J01AA.profile.ud50
adip_vs_fibro_up	12021175	Upregulated following 7-day differentiation of murine 3T3-L1 fibroblasts into adipocytes	59	0.291689326148218	0	0	1	J01AA.profile.ud50
adip_vs_preadip_dn	12021175	Downregulated in mature murine adipocytes (7 day differentiation) vs. preadipocytes (6 hr differentiation)	84	0.41528649824492	0	0	1	J01AA.profile.ud50
adip_vs_preadip_up	12021175	Upregulated in mature murine adipocytes (7 day differentiation) vs. preadipocytes (6 hr differentiation)	57	0.281801552380482	0	0	1	J01AA.profile.ud50
adr_res_xenografts_dn	11809704	Down-regulation is correlated with resistance of human cancer xenografts to adriamycin	10	0.049438868838681	0	0	1	J01AA.profile.ud50
aged_mouse_cerebellum_dn	10888876	Downregulated in the cerebellum of aged adult mice (30-month) vs. young adult (5-month)	87	0.430118158896524	0	0	1	J01AA.profile.ud50
aged_mouse_cerebellum_up	10888876	Upregulated in the cerebellum of aged adult mice (30-month) vs. young adult (5-month)	92	0.454837593315865	0	0	1	J01AA.profile.ud50
aged_mouse_cortex_dn	11172053	Down-regulated in the cerebral cortex of aged (22 months) BALB/c mice, compared to young (2 months) controls	98	0.484500914619074	1	2.06397959183673	0.384735200509055	J01AA.profile.ud50
aged_mouse_cortex_up	11172053	Up-regulated in the cerebral cortex of aged (22 months) BALB/c mice, compared to young (2 months) controls	71	0.351015968754635	0	0	1	J01AA.profile.ud50
aged_mouse_hippocampus_any_dn	15960800	Down-regulated in the hippocampus of 16-month aged mice from any of four strains (S8, S10, SR1, B6J), versus 3-month young controls	60	0.296633213032086	0	0	1	J01AA.profile.ud50
aged_mouse_hippocampus_any_up	15960800	Up-regulated in the hippocampus of 16-month aged mice from any of four strains (S8, S10, SR1, B6J), versus 3-month young controls	78	0.385623176941712	1	2.59320512820513	0.320623334181982	J01AA.profile.ud50
aged_mouse_hippocampus_multi_dn	15960800	Down-regulated in the hippocampus of 16-month aged mice from at least two of four strains (S8, S10, SR1, B6J), versus 3-month young controls	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
aged_mouse_hippocampus_multi_up	15960800	Up-regulated in the hippocampus of 16-month aged mice from at least two of four strains (S8, S10, SR1, B6J), versus 3-month young controls	38	0.187867701586988	1	5.3228947368421	0.171661702549689	J01AA.profile.ud50
aged_mouse_hypoth_dn	11172053	Down-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls	62	0.306520986799822	1	3.26241935483871	0.264556231995443	J01AA.profile.ud50
aged_mouse_hypoth_up	11172053	Up-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls	79	0.39056706382558	0	0	1	J01AA.profile.ud50
aged_mouse_muscle_dn	10464095	Downregulated in the gastrocnemius muscle of aged adult mice (30-month) vs. young adult (5-month)	59	0.291689326148218	0	0	1	J01AA.profile.ud50
aged_mouse_muscle_up	10464095	Upregulated in the gastrocnemius muscle of aged adult mice (30-month) vs. young adult (5-month)	51	0.252138231077273	0	0	1	J01AA.profile.ud50
aged_mouse_neocortex_dn	10888876	Downregulated in the neocortex of aged adult mice (30-month) vs. young adult (5-month)	102	0.504276462154546	0	0	1	J01AA.profile.ud50
aged_mouse_neocortex_up	10888876	Upregulated in the neocortex of aged adult mice (30-month) vs. young adult (5-month)	111	0.548771444109359	0	0	1	J01AA.profile.ud50
aged_mouse_retina_any_dn	15960800	Down-regulated in the retina of 16-month aged mice from any of four strains (S8, S10, SR1, B6J), versus 3-month young controls	24	0.118653285212834	0	0	1	J01AA.profile.ud50
aged_mouse_retina_any_up	15960800	Up-regulated in the retina of 16-month aged mice from any of four strains (S8, S10, SR1, B6J), versus 3-month young controls	36	0.177979927819252	0	0	1	J01AA.profile.ud50
aged_mouse_retina_multi_up	15960800	Up-regulated in the retina of 16-month aged mice from at least two of four strains (S8, S10, SR1, B6J), versus 3-month young controls	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
aged_rhesus_dn	11309484	Downregulated in the vastus lateralis muscle of aged vs. young adult rhesus monkeys	232	1.1469817570574	1	0.871853448275862	0.683308261103323	J01AA.profile.ud50
aged_rhesus_up	11309484	Upregulated in the vastus lateralis muscle of aged vs. young adult rhesus monkeys	390	1.92811588470856	2	1.03728205128205	0.57483262752213	J01AA.profile.ud50
ageing_brain_dn	15190254	Age-downregulated in the human frontal cortex	244	1.20630839966382	1	0.828975409836066	0.701593966272893	J01AA.profile.ud50
ageing_brain_up	15190254	Age-upregulated in the human frontal cortex	446	2.20497355020517	1	0.453520179372197	0.890347845086297	J01AA.profile.ud50
ageing_kidney_dn	15562319	Down-regulation is associated with increasing age in normal human kidney tissue from 74 patients	238	1.17664507836061	3	2.5496218487395	0.115051459057555	J01AA.profile.ud50
ageing_kidney_specific_dn	15562319	Down-regulation is associated with increasing age in normal human kidney tissue from 74 patients, and expression is higher in kidney than in whole blood	248	1.22608394719929	3	2.44681451612903	0.125793925005262	J01AA.profile.ud50
ageing_kidney_specific_up	15562319	Up-regulation is associated with increasing age in normal human kidney tissue from 74 patients, and expression is higher in kidney than in whole blood	277	1.36945666683146	0	0	1	J01AA.profile.ud50
ageing_kidney_up	15562319	Up-regulation is associated with increasing age in normal human kidney tissue from 74 patients	611	3.02071488604341	1	0.331047463175123	0.951597636064114	J01AA.profile.ud50
ageing_lymph_dn	12618007	Downregulated in human lymphocytes from old individuals, compared to young	30	0.148316606516043	0	0	1	J01AA.profile.ud50
ageing_lymph_up	12618007	Upregulated in human lymphocytes from old individuals, compared to young	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
alk1_hmvec_2hr_dn	16405919	Down-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC).	189	0.93439462105107	1	1.07021164021164	0.608085679359619	J01AA.profile.ud50
alk1_hmvec_2hr_up	16405919	Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC).	593	2.93172492213378	4	1.3643844856661	0.33743725336244	J01AA.profile.ud50
alk1_hmvec_4hr_dn	16405919	Down-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC).	189	0.93439462105107	1	1.07021164021164	0.608085679359619	J01AA.profile.ud50
alk1_hmvec_4hr_up	16405919	Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK1, which activates the Smad1/5 pathway, in human microvessel endothelial cells (HMVEC).	593	2.93172492213378	4	1.3643844856661	0.33743725336244	J01AA.profile.ud50
alk5_hmvec_2hr_dn	16405919	Down-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC).	202	0.998665150541356	0	0	1	J01AA.profile.ud50
alk5_hmvec_2hr_up	16405919	Up-regulated 2 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC).	347	1.71552874870223	0	0	1	J01AA.profile.ud50
alk5_hmvec_4hr_dn	16405919	Down-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC).	202	0.998665150541356	0	0	1	J01AA.profile.ud50
alk5_hmvec_4hr_up	16405919	Up-regulated 4 hr following constitutive activation of TGFbeta receptor ALK5,, which activates the Smad2/3 pathway, in human microvessel endothelial cells (HMVEC).	347	1.71552874870223	0	0	1	J01AA.profile.ud50
alzheimers_disease_dn	14769913	Downregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus	2117	10.4662085331488	11	1.05100141709967	0.475224722326668	J01AA.profile.ud50
alzheimers_disease_up	14769913	Upregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus	3137	15.5089731546942	14	0.902703219636595	0.684267406057737	J01AA.profile.ud50
alzheimers_incipient_dn	14769913	Downregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus	312	1.54249270776685	0	0	1	J01AA.profile.ud50
alzheimers_incipient_up	14769913	Upregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus	754	3.72769071043655	4	1.07305039787798	0.51198549857427	J01AA.profile.ud50
aom-dss_colon_10wks_dn	17506908	Down-regulated in mouse colonic mucosa after 10 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls.	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
aom-dss_colon_10wks_up	17506908	Up-regulated in mouse colonic mucosa after 10 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls.	22	0.108765511445098	0	0	1	J01AA.profile.ud50
aom-dss_colon_5wks_dn	17506908	Down-regulated in mouse colonic mucosa after 5 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls.	57	0.281801552380482	0	0	1	J01AA.profile.ud50
aom-dss_colon_5wks_up	17506908	Up-regulated in mouse colonic mucosa after 5 weeks of treatment with the colon carcinogens azoxymethane (AOM) and 2% dextran sodium sulfate (DSS) vs. untreated controls.	133	0.657536955554457	0	0	1	J01AA.profile.ud50
arthritis_mouse_common_dn	16805906	Dn-regulated in joint tissue from both severely arthritic HTLV-I transgenic mice and IL-1Ra knock-out mice, versus wild-type littermate controls.	1	0.0049438868838681	0	0	1	J01AA.profile.ud50
arthritis_mouse_common_up	16805906	Up-regulated in joint tissue from both severely arthritic HTLV-I transgenic mice and IL-1Ra knock-out mice, versus wild-type littermate controls.	459	2.26924407969546	2	0.881350762527233	0.662729678023695	J01AA.profile.ud50
arthritis_mouse_htlv1_dn	16805906	Down-regulated in joint tissue from severely arthritic 6-9 week-old HTLV-I transgenic mice, versus wild-type littermate controls.	159	0.786078014535027	0	0	1	J01AA.profile.ud50
arthritis_mouse_htlv1_up	16805906	Up-regulated in joint tissue from severely arthritic 6-9 week-old HTLV-I transgenic mice, versus wild-type littermate controls.	251	1.24091560785089	2	1.61171314741036	0.352321710326913	J01AA.profile.ud50
arthritis_mouse_il1ko_dn	16805906	Down-regulated in joint tissue from severely arthritic 13 week-old IL-1Ra knock-out mice, versus wild-type littermate controls.	105	0.51910812280615	0	0	1	J01AA.profile.ud50
arthritis_mouse_il1ko_up	16805906	Up-regulated in joint tissue from severely arthritic 13 week-old IL-1Ra knock-out mice, versus wild-type littermate controls.	271	1.33979334552825	2	1.49276752767528	0.387503854470778	J01AA.profile.ud50
as3_fibro_c1	12016162	Upregulated strongly by sodium arsenite in fibroblasts (Cluster 1)	67	0.331240421219163	0	0	1	J01AA.profile.ud50
as3_fibro_c2	12016162	Upregulated moderately by sodium arsenite in fibroblasts (Cluster 2)	67	0.331240421219163	0	0	1	J01AA.profile.ud50
as3_fibro_c3	12016162	Upregulated late by sodium arsenite in fibroblasts (Cluster 3)	95	0.469669253967469	0	0	1	J01AA.profile.ud50
as3_fibro_c4	12016162	Downregulated early by sodium arsenite in fibroblasts (Cluster 4)	35	0.173036040935383	0	0	1	J01AA.profile.ud50
as3_fibro_c5	12016162	Downregulated moderately by sodium arsenite in fibroblasts (Cluster 5)	20	0.098877737677362	0	0	1	J01AA.profile.ud50
as3_fibro_dn	12016162	Downregulated by sodium arsenite in fibroblasts (Clusters 4, 5, and 6)	59	0.291689326148218	0	0	1	J01AA.profile.ud50
as3_fibro_up	12016162	Upregulated by sodium arsenite in fibroblasts (Clusters 1, 2, and 3)	95	0.469669253967469	0	0	1	J01AA.profile.ud50
as3_hek293_dn	12679051	Downregulated in HEK293 cells by treatment with arsenite	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
as3_hek293_up	12679051	Upregulated in HEK293 cells by treatment with arsenite	19	0.0939338507934939	0	0	1	J01AA.profile.ud50
atria_up	15103417	Upregulated in the atria of healthy hearts, compared to venticles	384	1.89845256340535	0	0	1	J01AA.profile.ud50
avoidance_dn	15720406	Down-regulated in hippocampi from the Syracuse high-avoidance (SHA) rat line, versus Syracuse low-avoidance (SLA) rat line.	40	0.197755475354724	0	0	1	J01AA.profile.ud50
avoidance_up	15720406	Up-regulated in hippocampi from the Syracuse high-avoidance (SHA) rat line, versus Syracuse low-avoidance (SLA) rat line.	34	0.168092154051515	0	0	1	J01AA.profile.ud50
baf57_bt549_dn	16135788	Down-regulated following stable re-expression of BAF57 in Bt549 breast cancer cells that lack functional BAF57	554	2.73891333366293	6	2.19064981949458	0.0594454414649805	J01AA.profile.ud50
baf57_bt549_up	16135788	Up-regulated following stable re-expression of BAF57 in Bt549 breast cancer cells that lack functional BAF57	364	1.79957482572799	0	0	1	J01AA.profile.ud50
bap_hepg2_dn	17042939	Down-regulated at least 1.4-fold following treatment of HepG2 human hepatocellular carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	56	0.276857665496613	1	3.61196428571429	0.242358004255328	J01AA.profile.ud50
bap_hepg2_up	17042939	Up-regulated at least 1.4-fold following treatment of HepG2 human hepatocellular carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	83	0.410342611361052	0	0	1	J01AA.profile.ud50
bap_mcf7_dn	17042939	Down-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	135	0.667424729322193	0	0	1	J01AA.profile.ud50
bap_mcf7_up	17042939	Up-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with carcinogen benzo(a)pyrene (BaP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	87	0.430118158896524	1	2.32494252873563	0.350261239643424	J01AA.profile.ud50
bay-il2_pbmc_early_up	17471163	Up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2.	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
bay-il2_pbmc_late_dn	17471163	Down-regulated at 24-48 hours following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2.	205	1.01349681119296	0	0	1	J01AA.profile.ud50
bay-il2_pbmc_late_up	17471163	Up-regulated at 24-48 hours following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2.	130	0.642705294902853	1	1.55592307692308	0.474969688503152	J01AA.profile.ud50
bay-il2_pbmc_middle_dn	17471163	Down-regulated at 2-6 hours following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2.	64	0.316408760567558	0	0	1	J01AA.profile.ud50
bay-il2_pbmc_middle_up	17471163	Up-regulated at 2-6 hours following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist, compared to recombinant IL-2.	74	0.365847629406239	0	0	1	J01AA.profile.ud50
bay_pbmc_24hr_dn	17471163	Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	268	1.32496168487665	1	0.754738805970149	0.735058902244318	J01AA.profile.ud50
bay_pbmc_24hr_up	17471163	Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	202	0.998665150541356	1	1.00133663366337	0.632540423046607	J01AA.profile.ud50
bay_pbmc_2hr_dn	17471163	Down-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	398	1.9676669797795	4	2.03286432160804	0.136634862108969	J01AA.profile.ud50
bay_pbmc_2hr_up	17471163	Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	606	2.99599545162407	2	0.667557755775578	0.800992942215025	J01AA.profile.ud50
bay_pbmc_30min_dn	17471163	Down-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	10	0.049438868838681	0	0	1	J01AA.profile.ud50
bay_pbmc_30min_up	17471163	up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	82	0.405398724477184	0	0	1	J01AA.profile.ud50
bay_pbmc_48hr_dn	17471163	Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	318	1.57215602907005	2	1.27213836477987	0.466490540600097	J01AA.profile.ud50
bay_pbmc_48hr_up	17471163	Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	475	2.34834626983735	1	0.425831578947368	0.905027742181944	J01AA.profile.ud50
bay_pbmc_4hr_dn	17471163	Down-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	400	1.97755475354724	3	1.517025	0.317232940662357	J01AA.profile.ud50
bay_pbmc_4hr_up	17471163	Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	544	2.68947446482425	2	0.743639705882353	0.750187691387133	J01AA.profile.ud50
bay_pbmc_6hr_dn	17471163	Down-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	483	2.38789736490829	2	0.837556935817805	0.6896685481705	J01AA.profile.ud50
bay_pbmc_6hr_up	17471163	Up-regulated at 6 hr following treatment of peripheral blood mononuclear cells (PBMC) with BAY 50-4798, an IL-2 receptor agonist.	475	2.34834626983735	2	0.851663157894737	0.680891892509484	J01AA.profile.ud50
bcnu_glioma_mgmt_24hrs_dn	15980968	Down-regulated in an MGMT+ glioma cell line (T98G) at 24 hours following treatment with BCNU	54	0.266969891728877	0	0	1	J01AA.profile.ud50
bcnu_glioma_mgmt_24hrs_up	15980968	Up-regulated in an MGMT+ glioma cell line (T98G) at 24 hours following treatment with BCNU	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
bcnu_glioma_mgmt_48hrs_dn	15980968	Down-regulated in an MGMT+ glioma cell line (T98G) at 48 hours following treatment with BCNU	253	1.25080338161863	2	1.59897233201581	0.355874103682851	J01AA.profile.ud50
bcnu_glioma_mgmt_48hrs_up	15980968	Up-regulated in an MGMT+ glioma cell line (T98G) at 48 hours following treatment with BCNU	33	0.163148267167647	0	0	1	J01AA.profile.ud50
bcnu_glioma_nomgmt_24hrs_dn	15980968	Down-regulated in an MGMT-deficient glioma cell line (A172) at 24 hours following treatment with BCNU	22	0.108765511445098	0	0	1	J01AA.profile.ud50
bcnu_glioma_nomgmt_24hrs_up	15980968	Up-regulated in an MGMT-deficient glioma cell line (A172) at 24 hours following treatment with BCNU	25	0.123597172096702	0	0	1	J01AA.profile.ud50
bcnu_glioma_nomgmt_48hrs_dn	15980968	Down-regulated in an MGMT-deficient glioma cell line (A172) at 48 hours following treatment with BCNU	50	0.247194344193405	0	0	1	J01AA.profile.ud50
bcnu_glioma_nomgmt_48hrs_up	15980968	Up-regulated in an MGMT-deficient glioma cell line (A172) at 48 hours following treatment with BCNU	31	0.153260493399911	0	0	1	J01AA.profile.ud50
bcrabl_hl60_affy_dn	15155749	Down-regulated by expression of p210(BCR-ABL) in human leukemia (HL-60) cells; detected by Affymetrix arrays	19	0.0939338507934939	0	0	1	J01AA.profile.ud50
bcrabl_hl60_affy_up	15155749	Up-regulated by expression of p210(BCR-ABL) in human leukemia (HL-60) cells; detected by Affymetrix arrays	36	0.177979927819252	1	5.61861111111111	0.163410139213889	J01AA.profile.ud50
bcrabl_hl60_cdna_dn	15155749	Down-regulated by expression of p210(BCR-ABL) in human leukemia (HL-60) cells; detected by spotted cDNA arrays	54	0.266969891728877	0	0	1	J01AA.profile.ud50
bcrabl_hl60_cdna_up	15155749	Up-regulated by expression of p210(BCR-ABL) in human leukemia (HL-60) cells; detected by spotted cDNA arrays	39	0.192811588470856	0	0	1	J01AA.profile.ud50
bep_mcf7_dn	17042939	Down-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with non-carcinogenic benzo(e)pyrene (BeP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	34	0.168092154051515	0	0	1	J01AA.profile.ud50
bep_mcf7_up	17042939	Up-regulated at least 1.4-fold following treatment of MCF-7 human breast carcinoma cells with non-carcinogenic benzo(e)pyrene (BeP), at any time point from 6-48 hours and at any concentration from 0.25-5 microM.	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
bleo_human_lymph_high_24hrs_dn	15515172	Down-regulated at 24 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin	4	0.0197755475354724	0	0	1	J01AA.profile.ud50
bleo_human_lymph_high_24hrs_up	15515172	Up-regulated at 24 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin	197	0.973945716122015	2	2.05350253807107	0.254632834533494	J01AA.profile.ud50
bleo_human_lymph_high_4hrs_dn	15515172	Down-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
bleo_human_lymph_high_4hrs_up	15515172	Up-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of bleomycin	32	0.158204380283779	0	0	1	J01AA.profile.ud50
bleo_human_lymph_low_24hrs_up	15515172	Up-regulated at 24 hours following treatment of human lymphocytes (TK6) with a low dose of bleomycin	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
bleo_mouse_lymph_high_24hrs_dn	15515172	Down-regulated at 24 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a high dose of bleomycin	71	0.351015968754635	0	0	1	J01AA.profile.ud50
bleo_mouse_lymph_high_4hrs_up	15515172	Up-regulated at 4 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a high dose of bleomycin	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
bleo_mouse_lymph_low_24hrs_dn	15515172	Down-regulated at 24 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a low dose of bleomycin	56	0.276857665496613	0	0	1	J01AA.profile.ud50
bleo_mouse_lymph_low_4hrs_up	15515172	Up-regulated at 4 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a low dose of bleomycin	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
brcax_a_dn	12610208	Down-regulated in one group (A) of BRCAx tumors (familial non-BRCA1/BRCA2 breast cancer), compared to a second BRCAx group (B)	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
brcax_a_up	12610208	Up-regulated in one group (A) of BRCAx tumors (familial non-BRCA1/BRCA2 breast cancer), compared to a second BRCAx group (B)	30	0.148316606516043	1	6.74233333333333	0.13815897377783	J01AA.profile.ud50
brca1_irradiated_up	14871973	Up-regulated in germline-mutant BRCA1 tumor cells compared to non-BRCA1 control tumors, following 15 Gy irradiation.	105	0.51910812280615	0	0	1	J01AA.profile.ud50
brca1ko_mef_dn	15520196	Down-regulated in mouse embryonic fibroblasts following targeted deletion of BRCA1 (exon 11) compared to wild-type MEFs	182	0.899787412863994	0	0	1	J01AA.profile.ud50
brca1ko_mef_up	15520196	Up-regulated in mouse embryonic fibroblasts following targeted deletion of BRCA1 (exon 11) compared to wild-type MEFs	19	0.0939338507934939	0	0	1	J01AA.profile.ud50
brca1_mes_up	11384963	Genes with reduced expression in mouse embryonic stem cells with a targeted deletion of BRCA1, whose expression was rescued by ectopic expression of a BRCA1 transgene	86	0.425174272012656	0	0	1	J01AA.profile.ud50
brca1_overexp_dn	12032322	Downregulated by induction of exogenous BRCA1 in EcR-293 cells	220	1.08765511445098	1	0.919409090909091	0.66390204570354	J01AA.profile.ud50
brca1_overexp_prostate_dn	15520196	Down-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls	168	0.83057299648984	0	0	1	J01AA.profile.ud50
brca1_overexp_prostate_up	15520196	Up-regulated with stable, ectopic overexpression of BRCA1 in DU-145 human prostate cancer cell lines, compared to neo-only controls	308	1.52271716023137	1	0.656720779220779	0.7827037574075	J01AA.profile.ud50
brca1_overexp_up	12032322	Upregulated by induction of exogenous BRCA1 in EcR-293 cells	328	1.62159489790874	2	1.23335365853659	0.482510084643076	J01AA.profile.ud50
brca1_sw480_dn	10644742	Down-regulated by infection of human colon adenocarcinoma cells (SW480) with Ad-BRCA1, versus Ad-LacZ control	33	0.163148267167647	1	6.12939393939394	0.150878416157636	J01AA.profile.ud50
brca1_sw480_up	10644742	Up-regulated by infection of human colon adenocarcinoma cells (SW480) with Ad-BRCA1, versus Ad-LacZ control	50	0.247194344193405	0	0	1	J01AA.profile.ud50
brca2_brca1_dn	12096084	Genes down-regulated in BRCA2-linked breast tumors, relative to BRCA1-linked tumors	83	0.410342611361052	2	4.87397590361446	0.063946934520759	J01AA.profile.ud50
brca2_brca1_up	12096084	Genes up-regulated in BRCA2-linked breast tumors, relative to BRCA1-linked tumors	99	0.489444801502942	1	2.04313131313131	0.387777000081364	J01AA.profile.ud50
brca2kd_dn	15670748	Down-regulated following transient RNAi knock-down of BRCA2 in both HMEC (human mammary epithelial) and BT549 (human breast carcinoma) cell lines	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
brca_brca1_neg	11823860	Genes whose expression is consistently negatively correlated with brca1 germline status in breast cancer - higher expression is associated with BRCA1 tumors 	250	1.23597172096702	1	0.80908	0.710336994157968	J01AA.profile.ud50
brca_brca1_pos	11823860	Genes whose expression is consistently positively correlated with brca1 germline status in breast cancer - higher expression is associated with sporadic tumors 	182	0.899787412863994	2	2.22274725274725	0.227348044354149	J01AA.profile.ud50
brca_er_neg	11823860	Genes whose expression is consistently negatively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-negative tumors	1519	7.50976417659564	4	0.532639894667544	0.941664155840544	J01AA.profile.ud50
brca_er_pos	11823860	Genes whose expression is consistently positively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-positive tumors	842	4.16275275621694	7	1.68157957244656	0.127799331505775	J01AA.profile.ud50
brca_prognosis_neg	11823860	Genes whose expression is consistently negatively correlated with breast cancer outcomes - higher expression is associated with metastasis and poor prognosis	166	0.820685222722104	0	0	1	J01AA.profile.ud50
brca_prognosis_pos	11823860	Genes whose expression is consistently positively correlated with breast cancer outcomes - higher expression is associated with good prognosis	57	0.281801552380482	0	0	1	J01AA.profile.ud50
breastca_three_classes	11207349	Gene set that can be used to differentiate BRCA1-linked, BRCA2-linked, and sporadic primary breast cancers	70	0.346072081870767	1	2.88957142857143	0.293145464042583	J01AA.profile.ud50
breastca_two_classes	11207349	Gene set that can be used to differentiate BRCA1-linked and BRCA2-linked breast cancers	247	1.22114006031542	1	0.818906882591093	0.70599797842397	J01AA.profile.ud50
brg1_alab_dn	14673169	Down-regulated at 18 and 24 hours following adenovirus-mediated expression of BRG1 in ALAB breast cancer cells with mutant, inactive BRG1	65	0.321352647451426	0	0	1	J01AA.profile.ud50
brg1_alab_up	14673169	Up-regulated at 18 and 24 hours following adenovirus-mediated expression of BRG1 in ALAB breast cancer cells with mutant, inactive BRG1	91	0.449893706431997	1	2.22274725274725	0.363015207493356	J01AA.profile.ud50
brg1_h1299_up	15731117	Up-regulated by transient expression of BRG1 in H1299 lung cancer cells with mutant, inactive BRG1	50	0.247194344193405	0	0	1	J01AA.profile.ud50
brg1_sw13_up	11509180	Up-regulated by transient expression of BRG1 at 24 hours in human, BRG1-lacking SW-13 cells	51	0.252138231077273	0	0	1	J01AA.profile.ud50
but_tsa_up	11423116	Upregulated by the combination of TSA and butyrate in HT-29 cells	36	0.177979927819252	0	0	1	J01AA.profile.ud50
bws_imprinted	12668598	Imprinted genes on Chr. 11p15 that are dysregulated in Beckwith-Wiedmann syndrome	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
calres_mouse_dn	10464095	Downregulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls	79	0.39056706382558	1	2.56037974683544	0.323982095569325	J01AA.profile.ud50
calres_mouse_neocortex_dn	10888876	Downregulated in the neocortex of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls	114	0.563603104760963	1	1.77429824561404	0.431640369721972	J01AA.profile.ud50
calres_mouse_neocortex_up	10888876	Upregulated in the neocortex of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls	99	0.489444801502942	0	0	1	J01AA.profile.ud50
calres_mouse_up	10464095	Upregulated in the gastrocnemius muscle of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls	51	0.252138231077273	0	0	1	J01AA.profile.ud50
calres_presenillin_ko_hippocampus_dn	17499883	Down-regulated by calorie restriction in the hippocampus of 8 month-old presenillin-1 and -2 conditional double knock-out mice, compared to normal-diet controls.	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
calres_presenillin_ko_hippocampus_up	17499883	Up-regulated by calorie restriction in the hippocampus of 8 month-old presenillin-1 and -2 conditional double knock-out mice, compared to normal-diet controls.	137	0.677312503089929	1	1.47642335766423	0.492872242587475	J01AA.profile.ud50
calres_rhesus_dn	11309484	Downregulated in the vastus lateralis muscle of middle-aged rhesus monkeys subjected to caloric restriction since young adulthood vs. age-matched controls	110	0.543827557225491	0	0	1	J01AA.profile.ud50
calres_rhesus_up	11309484	Upregulated in the vastus lateralis muscle of middle-aged rhesus monkeys subjected to caloric restriction since young adulthood vs. age-matched controls	122	0.603154199831908	0	0	1	J01AA.profile.ud50
camptothecin_probcell_dn	12447701	Down-regulated in pro-B cells (FL5.12) following treatment with camptothecin	52	0.257082117961141	0	0	1	J01AA.profile.ud50
camptothecin_probcell_up	12447701	Up-regulated in pro-B cells (FL5.12) following treatment with camptothecin	28	0.138428832748307	0	0	1	J01AA.profile.ud50
cancerdrugs_probcell_dn	12447701	Down-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12)	26	0.128541058980571	0	0	1	J01AA.profile.ud50
cancerdrugs_probcell_up	12447701	Up-regulated by at least two of four cancer drugs (cisplatin, camptothecin, methotrextate and/or paclitaxel) in pro-B cells (FL5.12)	24	0.118653285212834	0	0	1	J01AA.profile.ud50
cancer_neoplastic_meta_up	15184677	Sixty-seven genes commonly upregulated in cancer relative to normal tissue, from a meta-analysis of the OncoMine gene expression database	115	0.568546991644831	1	1.75886956521739	0.434450275443423	J01AA.profile.ud50
cancer_undifferentiated_meta_up	15184677	Sixty-nine genes commonly upregulated in undifferentiated cancer relative to well-differentiated cancer, from a meta-analysis of the OncoMine gene expression database	98	0.484500914619074	0	0	1	J01AA.profile.ud50
cantharidin_dn	14639605	Downregulated in HL-60 promyeloid leukemic cells after treatment with the cytotoxic drug cantharidin	83	0.410342611361052	0	0	1	J01AA.profile.ud50
cantharidin_up	14639605	Upregulated in HL-60 promyeloid leukemic cells after treatment with the cytotoxic drug cantharidin	27	0.133484945864439	0	0	1	J01AA.profile.ud50
caries_pulp_dn	15869869	Down-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth	131	0.647649181786721	0	0	1	J01AA.profile.ud50
caries_pulp_high_up	15869869	Highly up-regulated (>4-fold) in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth	168	0.83057299648984	1	1.2039880952381	0.565097285664894	J01AA.profile.ud50
caries_pulp_up	15869869	Up-regulated in pulpal tissue from extracted carious teeth (cavities), compared to tissue from extracted healthy teeth	410	2.02699362238592	2	0.986682926829268	0.60193076924848	J01AA.profile.ud50
cisplatin_probcell_dn	12447701	Down-regulated in pro-B cells (FL5.12) following treatment with cisplatin	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
cisplatin_probcell_up	12447701	Up-regulated in pro-B cells (FL5.12) following treatment with cisplatin	23	0.113709398328966	0	0	1	J01AA.profile.ud50
cis_resist_gastric_dn	14734480	Downregulated in gastric cancer cell lines reistant to cisplatin, compared to parent chemosensitive lines	10	0.049438868838681	0	0	1	J01AA.profile.ud50
cis_resist_gastric_up	14734480	Upregulated in gastric cancer cell lines reistant to cisplatin, compared to parent chemosensitive lines	29	0.143372719632175	0	0	1	J01AA.profile.ud50
cis_resist_lung_dn	14737109	Transient down-regulation is associated with transient cisplatin resistance in a human squamous cell lung cancer line (NCI-H2170)	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
cis_resist_lung_up	14737109	Transient up-regulation is associated with transient cisplatin resistance in a human squamous cell lung cancer line (NCI-H2170)	21	0.10382162456123	0	0	1	J01AA.profile.ud50
cis_res_xenografts_dn	11809704	Down-regulation is correlated with resistance of human cancer xenografts to cisplatin	3	0.0148316606516043	0	0	1	J01AA.profile.ud50
cis_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to cisplatin	10	0.049438868838681	0	0	1	J01AA.profile.ud50
cis_xpc_dn	15107491	Reduced expression in XPC-defective fibroblasts, compared to normal fibroblasts, following treatment with cisplatin	363	1.79463093884412	0	0	1	J01AA.profile.ud50
cis_xpc_up	15107491	Increased expression in XPC-defective fibroblasts, compared to normal fibroblasts, following treatment with cisplatin	242	1.19642062589608	0	0	1	J01AA.profile.ud50
cited1_ko_het_dn	16278680	Down-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus heterozygotes	56	0.276857665496613	0	0	1	J01AA.profile.ud50
cited1_ko_het_up	16278680	Up-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus heterozygotes	43	0.212587136006328	0	0	1	J01AA.profile.ud50
cited1_ko_wt_dn	16278680	Down-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus wild-type controls	21	0.10382162456123	0	0	1	J01AA.profile.ud50
cited1_ko_wt_up	16278680	Up-regulated in pubertal mammary glands from CITED1 knockout mice, which display disturbed mammary development, versus wild-type controls	32	0.158204380283779	0	0	1	J01AA.profile.ud50
cmv_24hrs_dn	9826724	Downregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV	140	0.692144163741534	0	0	1	J01AA.profile.ud50
cmv_24hrs_up	9826724	Upregulated at 24hrs following infection of primary human foreskin fibroblasts with CMV	133	0.657536955554457	0	0	1	J01AA.profile.ud50
cmv_40min_dn	9826724	Downregulated at 40 min following infection of primary human foreskin fibroblasts with CMV	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
cmv_8hrs_dn	9826724	Downregulated at 8hrs following infection of primary human foreskin fibroblasts with CMV	102	0.504276462154546	0	0	1	J01AA.profile.ud50
cmv_8hrs_up	9826724	Upregulated at 8hrs following infection of primary human foreskin fibroblasts with CMV	56	0.276857665496613	0	0	1	J01AA.profile.ud50
cmv_all_dn	9826724	Downregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV	213	1.0530479062639	0	0	1	J01AA.profile.ud50
cmv_all_up	9826724	Upregulated at any timepoint following infection of primary human foreskin fibroblasts with CMV	173	0.855292430909181	0	0	1	J01AA.profile.ud50
cmv-chx_hcmv_6hrs_dn	11711622	Down-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus in the presence of cyclohexamide (CHX)	26	0.128541058980571	0	0	1	J01AA.profile.ud50
cmv-chx_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus in the presence of cyclohexamide (CHX)	10	0.049438868838681	0	0	1	J01AA.profile.ud50
cmv_hcmv_6hrs_dn	11711622	Down-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV)	109	0.538883670341623	2	3.71137614678899	0.101855734162404	J01AA.profile.ud50
cmv_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following infection with human cytomegalovirus (CMV)	46	0.227418796657932	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_10hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours	30	0.148316606516043	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_10hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 10 hours	23	0.113709398328966	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_12hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 12 hours	33	0.163148267167647	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_12hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 12 hours	45	0.222474909774064	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_14hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours	95	0.469669253967469	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_14hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 14 hours	84	0.41528649824492	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_16hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours	38	0.187867701586988	1	5.3228947368421	0.171661702549689	J01AA.profile.ud50
cmv_hcmv_timecourse_16hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 16 hours	93	0.459781480199733	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_18hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 18 hours	44	0.217531022890196	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_18hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 18 hours	142	0.70203193750927	2	2.84887323943662	0.156253379773236	J01AA.profile.ud50
cmv_hcmv_timecourse_1hr_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 1 hour	73	0.360903742522371	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_1hr_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 1 hour	21	0.10382162456123	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_20hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 20 hours	87	0.430118158896524	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_20hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 20 hours	174	0.860236317793049	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_24hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 24 hours	82	0.405398724477184	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_24hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 24 hours	123	0.608098086715776	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_2hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 2 hours	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_30min_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 30 minutes	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_30min_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 30 minutes	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_48hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 48 hours	235	1.161813417709	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_48hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 48 hours	135	0.667424729322193	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_4hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours	69	0.341128194986899	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_4hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 4 hours	26	0.128541058980571	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_6hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 6 hours	95	0.469669253967469	2	4.25831578947368	0.0807619697726046	J01AA.profile.ud50
cmv_hcmv_timecourse_6hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 6 hours	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_8hrs_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 8 hours	27	0.133484945864439	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_8hrs_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints), with maximum change at 8 hours	63	0.31146487368369	0	0	1	J01AA.profile.ud50
cmv_hcmv_timecourse_all_dn	11711622	Down-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints)	839	4.14792109556533	3	0.723253873659118	0.783502510465532	J01AA.profile.ud50
cmv_hcmv_timecourse_all_up	11711622	Up-regulated in fibroblasts following infection with human cytomegalovirus (at least 3-fold, with Affymetrix change call, in at least two consectutive timepoints)	895	4.42477876106195	2	0.452	0.935476852977134	J01AA.profile.ud50
cmv_ie86_up	11867723	Upregulated by expression of cytomegalovirus IE86 protein in primary human fibroblasts	82	0.405398724477184	0	0	1	J01AA.profile.ud50
cmv_uv-cmv_common_hcmv_6hrs_dn	11711622	Down-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV	54	0.266969891728877	0	0	1	J01AA.profile.ud50
cmvuv-cmv_common_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following infection with either human cytomegalovirus (CMV) or UV-inactivated CMV	37	0.18292381470312	0	0	1	J01AA.profile.ud50
cmv-uv_hcmv_6hrs_dn	11711622	Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus	207	1.0233845849607	0	0	1	J01AA.profile.ud50
cmv-uv_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated human cytomegalovirus	226	1.11731843575419	0	0	1	J01AA.profile.ud50
cocaine_brain_4wks_up	14566342	Up-regulated in the nucleus accumbens of mice after 4 weeks of cocaine treatment	112	0.553715330993227	0	0	1	J01AA.profile.ud50
cocaine_brain_5d_up	14566342	Up-regulated in the nucleus accumbens of mice after 5 days of cocaine treatment	113	0.558659217877095	1	1.79	0.428816503123482	J01AA.profile.ud50
cortex_enrichment_early_dn	11070096	Down-regulated in the cortex of mice that are exposed to an enriched environmental habitat for 3 or 6 hours	22	0.108765511445098	1	9.19409090909091	0.103301203426202	J01AA.profile.ud50
cortex_enrichment_early_up	11070096	Up-regulated in the cortex of mice that are exposed to an enriched environmental habitat for 3 or 6 hours	25	0.123597172096702	0	0	1	J01AA.profile.ud50
cortex_enrichment_late_dn	11070096	Down-regulated in the cortex of mice that are exposed to an enriched environmental habitat for 2 or 14 days	10	0.049438868838681	0	0	1	J01AA.profile.ud50
cortex_enrichment_late_up	11070096	Up-regulated in the cortex of mice that are exposed to an enriched environmental habitat for 2 or 14 days	34	0.168092154051515	0	0	1	J01AA.profile.ud50
cox1_ko_cortex_dn	17266762	Down-regulated in the cerebral cortex of COX1-/- mice compared to wild-type controls.	57	0.281801552380482	1	3.54859649122807	0.246103700580757	J01AA.profile.ud50
cox1_ko_cortex_up	17266762	Up-regulated in the cerebral cortex of COX1-/- mice compared to wild-type controls.	80	0.395510950709448	0	0	1	J01AA.profile.ud50
cox1_ko_hippocampus_dn	17266762	Down-regulated in the hippocampus of COX1-/- mice compared to wild-type controls.	77	0.380679290057844	1	2.62688311688312	0.31724788495548	J01AA.profile.ud50
cox1_ko_hippocampus_up	17266762	Up-regulated in the hippocampus of COX1-/- mice compared to wild-type controls.	81	0.400454837593316	0	0	1	J01AA.profile.ud50
cox2_ko_cortex_dn	17266762	Down-regulated in the cerebral cortex of COX2-/- mice compared to wild-type controls.	39	0.192811588470856	0	0	1	J01AA.profile.ud50
cox2_ko_cortex_up	17266762	Up-regulated in the cerebral cortex of COX2-/- mice compared to wild-type controls.	129	0.637761408018985	0	0	1	J01AA.profile.ud50
cox2_ko_hippocampus_dn	17266762	Down-regulated in the hippocampus of COX2-/- mice compared to wild-type controls.	84	0.41528649824492	1	2.40797619047619	0.340528458282614	J01AA.profile.ud50
cox2_ko_hippocampus_up	17266762	Up-regulated in the hippocampus of COX2-/- mice compared to wild-type controls.	79	0.39056706382558	0	0	1	J01AA.profile.ud50
cpm_res_xenografts_dn	11809704	Down-regulation is correlated with resistance of human cancer xenografts to cyclophosphamide	3	0.0148316606516043	0	0	1	J01AA.profile.ud50
cpm_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to cyclophosphamide	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
cpr_low_liver_dn	16006652	Down-regulated in mouse liver tissue from mice with reduced liver expression of NADPH-cytochrome P450 reductase (CPR), versus normal controls	40	0.197755475354724	0	0	1	J01AA.profile.ud50
cpr_low_liver_up	16006652	Up-regulated in mouse liver tissue from mice with reduced liver expression of NADPH-cytochrome P450 reductase (CPR), versus normal controls	32	0.158204380283779	1	6.3209375	0.146659597735406	J01AA.profile.ud50
cpr_null_liver_dn	16006652	Down-regulated in mouse liver tissue from mice in which NADPH-cytochrome P450 reductase (CPR) was specifically deleted in the liver by cre-lox recombination, versus lox-only controls	26	0.128541058980571	0	0	1	J01AA.profile.ud50
cpr_null_liver_up	16006652	Up-regulated in mouse liver tissue from mice in which NADPH-cytochrome P450 reductase (CPR) was specifically deleted in the liver by cre-lox recombination, versus lox-only controls	64	0.316408760567558	1	3.16046875	0.2718101578629	J01AA.profile.ud50
cpr_null-low_liver_dn	16006652	Down-regulated in mouse liver tissue from mice in which NADPH-cytochrome P450 reductase (CPR) was specifically deleted in the liver by cre-lox recombination, versus mice with low expression of CPR	4	0.0197755475354724	0	0	1	J01AA.profile.ud50
cpr_null-low_liver_up	16006652	Up-regulated in mouse liver tissue from mice in which NADPH-cytochrome P450 reductase (CPR) was specifically deleted in the liver by cre-lox recombination, versus mice with low expression of CPR	34	0.168092154051515	1	5.94911764705882	0.155076377218804	J01AA.profile.ud50
creb_brain_2wks_up	14566342	Up-regulated in the nucleus accumbens of mice after 2 weeks of induction of transgenic CREB	39	0.192811588470856	0	0	1	J01AA.profile.ud50
creb_brain_8wks_dn	14566342	Down-regulated in the nucleus accumbens of mice after 8 weeks of induction of transgenic CREB	85	0.420230385128788	0	0	1	J01AA.profile.ud50
creb_brain_8wks_up	14566342	Up-regulated in the nucleus accumbens of mice after 8 weeks of induction of transgenic CREB	114	0.563603104760963	0	0	1	J01AA.profile.ud50
csb_reliable_dn	16772382	Down-regulated reliably by stable expression of wt CSB in hTERT-immortalized CS1AN CSB-null fibroblasts vs. eGFP-expressing controls (7 of 9 pairwise comparisons).	558	2.7586888811984	2	0.724982078853047	0.762555319918109	J01AA.profile.ud50
csb_reliable_up	16772382	Up-regulated reliably by stable expression of wt CSB in hTERT-immortalized CS1AN CSB-null fibroblasts vs. eGFP-expressing controls (7 of 9 pairwise comparisons).	513	2.53621397142433	2	0.788576998050682	0.720817708889494	J01AA.profile.ud50
csb_robust_dn	16772382	Down-regulated robustly by stable expression of wt CSB in hTERT-immortalized CS1AN CSB-null fibroblasts vs. eGFP-expressing controls (9 of 9 pairwise comparisons).	169	0.835516883373708	1	1.19686390532544	0.567247395490054	J01AA.profile.ud50
csb_robust_up	16772382	Up-regulated robustly by stable expression of wt CSB in hTERT-immortalized CS1AN CSB-null fibroblasts vs. eGFP-expressing controls (9 of 9 pairwise comparisons).	140	0.692144163741534	0	0	1	J01AA.profile.ud50
dac_bladder_up	11861364	Upregulated by DAC treatment in T24 bladder carcinoma cells	60	0.296633213032086	0	0	1	J01AA.profile.ud50
dac_cgi_bladder_up	11861364	Upregulated by DAC treatment in T24 bladder carcinoma cells, with 5' CpG island	26	0.128541058980571	0	0	1	J01AA.profile.ud50
dac_cgi_fibro_dn	11861364	Downregulated by DAC treatment in LD419 fibroblast cells, with 5' CpG island	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
dac_cgi_fibro_up	11861364	Upregulated by DAC treatment in LD419 fibroblast cells, with 5' CpG island	20	0.098877737677362	0	0	1	J01AA.profile.ud50
dac_fibro_dn	11861364	Downregulated by DAC treatment in LD419 fibroblast cells	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
dac_fibro_up	11861364	Upregulated by DAC treatment in LD419 fibroblast cells	34	0.168092154051515	0	0	1	J01AA.profile.ud50
dac_ifn_bladder_up	11861364	Interferon-regulated genes upregulated by DAC treatment in T24 bladder carcinoma cells	34	0.168092154051515	0	0	1	J01AA.profile.ud50
dac_ifn_fibro_up	11861364	Interferon-regulated genes upregulated by DAC treatment in LD419 fibroblast cells	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
dac_panc50_up	12839967	50 "most interesting" genes upregulated by DAC treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells	80	0.395510950709448	0	0	1	J01AA.profile.ud50
dac_panc_up	12839967	Upregulated by DAC treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells	654	3.23330202204974	5	1.54640672782875	0.225000713251991	J01AA.profile.ud50
dex_keratinocyte_1hr_dn	17095510	Down-regulated in primary human keratinocytes at 1 hour following treatment with 0.1 microM dexamethasone	24	0.118653285212834	0	0	1	J01AA.profile.ud50
dex_keratinocyte_1hr_up	17095510	Up-regulated in primary human keratinocytes at 1 hour following treatment with 0.1 microM dexamethasone	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
dex_keratinocyte_4hr_dn	17095510	Down-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone	69	0.341128194986899	0	0	1	J01AA.profile.ud50
dex_keratinocyte_4hr_up	17095510	Up-regulated in primary human keratinocytes at 4 hours following treatment with 0.1 microM dexamethasone	35	0.173036040935383	1	5.77914285714286	0.159253584035342	J01AA.profile.ud50
dfosb_brain_2wks_up	14566342	Up-regulated in the nucleus accumbens of mice after 2 weeks of induction of transgenic deltaFosB	51	0.252138231077273	0	0	1	J01AA.profile.ud50
dfosb_brain_8wks_up	14566342	Up-regulated in the nucleus accumbens of mice after 8 weeks of induction of transgenic deltaFosB	73	0.360903742522371	0	0	1	J01AA.profile.ud50
diab_neph_dn	15042541	Downregulated in the glomeruli of cadaver kidneys from patients with diabetic nephropathy, compared to normal controls	829	4.09848222672665	3	0.731978287092883	0.776699076282311	J01AA.profile.ud50
diab_neph_up	15042541	Upregulated in the glomeruli of cadaver kidneys from patients with diabetic nephropathy, compared to normal controls	116	0.573490878528699	2	3.48741379310345	0.112908680921223	J01AA.profile.ud50
dixoin_chloracne_pbmnc_dn	17101203	Down-regulated in peripheral blood mononuclear cells of subjects who developed chloracne as a result of dioxin exposure, compared to subjects who did not.	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
dixoin_chloracne_pbmnc_up	17101203	Up-regulated in peripheral blood mononuclear cells of subjects who developed chloracne as a result of dioxin exposure, compared to subjects who did not.	34	0.168092154051515	0	0	1	J01AA.profile.ud50
dixoin_pbmnc_dn	17101203	Down-regulated in peripheral blood mononuclear cells of subjects with high exposure to dioxin, compared to low-exposure controls.	117	0.578434765412567	2	3.45760683760684	0.114512169369275	J01AA.profile.ud50
dixoin_pbmnc_up	17101203	Up-regulated in peripheral blood mononuclear cells of subjects with high exposure to dioxin, compared to low-exposure controls.	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
dnmt1_ko_dn	11137995	Downregulated following conditional knock-out of DNMT1 in MEFs	38	0.187867701586988	0	0	1	J01AA.profile.ud50
dnmt1_ko_up	11137995	Upregulated following conditional knock-out of DNMT1 in MEFs	117	0.578434765412567	0	0	1	J01AA.profile.ud50
dox_resist_gastric_dn	14734480	Downregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines	43	0.212587136006328	0	0	1	J01AA.profile.ud50
dox_resist_gastric_up	14734480	Upregulated in gastric cancer cell lines reistant to doxorubicin, compared to parent chemosensitive lines	74	0.365847629406239	0	0	1	J01AA.profile.ud50
dsrna_dn	11487589	Downregulated by dsRNA (polyI:C) in IFN-null GRE cells	24	0.118653285212834	0	0	1	J01AA.profile.ud50
dsrna_up	11487589	Upregulated by dsRNA (polyI:C) in IFN-null GRE cells	68	0.336184308103031	0	0	1	J01AA.profile.ud50
e2f1_dna_up	11313881	DNA replication genes upregulated by E2F1 induction	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
egf_hdmec_up	14517420	Up-regulated in human dermal (foreskin) microvascular endothelial cells that were stimulated to proliferate with prolonged EGF treatment, versus non-stimulated quiescent controls.	105	0.51910812280615	1	1.92638095238095	0.40571458228544	J01AA.profile.ud50
elongina_ko_dn	12604609	Downregulated in MES cells from elongin-A knockout mice	267	1.32001779799278	0	0	1	J01AA.profile.ud50
elongina_ko_up	12604609	Upregulated in MES cells from elongin-A knockout mice	263	1.30024225045731	0	0	1	J01AA.profile.ud50
emt_dn	14562044	Down-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis)	89	0.440005932664261	1	2.27269662921348	0.356669828587795	J01AA.profile.ud50
emt_up	14562044	Up-regulated during the TGFbeta-induced epithelial-to-mesenchymal transition (EMT) of Ras-transformed mouse mammary epithelial (EpH4) cells (EMT is representative of late-stage tumor progression and metastasis)	105	0.51910812280615	0	0	1	J01AA.profile.ud50
erm_ko_sertoli_dn	16107850	Down-regulated in Sertoli cells from both 4 and 10 week old ERM knockout mice, compared to 4 week wild-type controls	29	0.143372719632175	0	0	1	J01AA.profile.ud50
erm_ko_testes_dn	16107850	Down-regulated in testes from 4 week old ERM knockout mice, compared to wild-type controls	24	0.118653285212834	0	0	1	J01AA.profile.ud50
esr_fibroblast_dn	15897889	Down-regulated in the environmental stress response in human fibroblasts (regulated similarly by gamma and UV rediation and 4-NQO)	21	0.10382162456123	0	0	1	J01AA.profile.ud50
esr_fibroblast_up	15897889	Up-regulated in the environmental stress response in human fibroblasts (regulated similarly by gamma and UV rediation and 4-NQO)	98	0.484500914619074	0	0	1	J01AA.profile.ud50
et743_blockstsa	12067978	Normally induced by the HDACi TSA, but induction is blocked by Et-743	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
et743_hela_dn	12198119	Downregulated by Et-743 in HeLa cells	28	0.138428832748307	0	0	1	J01AA.profile.ud50
et743_hela_up	12198119	Upregulated by Et-743 in HeLa cells	99	0.489444801502942	1	2.04313131313131	0.387777000081364	J01AA.profile.ud50
et743pt650_breastca_dn	11755394	Downregulated by both Et-743 and Pt-650 in MDA-MB-435 cells (Fig. 6G)	20	0.098877737677362	0	0	1	J01AA.profile.ud50
et743pt650_colonca_dn	11755394	Downregulated by both Et-743 and Pt-650 in HCT116 cells (Fig. 6 A)	76	0.375735403173975	0	0	1	J01AA.profile.ud50
et743pt650_colonca_up	11755394	Upregulated by both Et-743 and Pt-650 in HCT116 cells (Fig. 6D)	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
et743_resist_dn	15661559	Down-regulated in two Et-743-resistant cell lines (chondrosarcoma and ovarian carcinoma) compared to sensitive parental lines	95	0.469669253967469	0	0	1	J01AA.profile.ud50
et743_resist_up	15661559	Up-regulated in two Et-743-resistant cell lines (chondrosarcoma and ovarian carcinoma) compared to sensitive parental lines	31	0.153260493399911	0	0	1	J01AA.profile.ud50
et743_sarcoma_24hrs_dn	15897246	Down-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines	163	0.8058535620705	0	0	1	J01AA.profile.ud50
et743_sarcoma_24hrs_up	15897246	Up-regulated at 24 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
et743_sarcoma_48hrs_dn	15897246	Down-regulated at48 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines	304	1.5029416126959	1	0.665361842105263	0.778352963912054	J01AA.profile.ud50
et743_sarcoma_6hrs_up	15897246	Up-regulated at 6 hours following treatment with Et-743 in at least 8 of 11 sarcoma cell lines	56	0.276857665496613	0	0	1	J01AA.profile.ud50
et743_sarcoma_72hrs_dn	15897246	Down-regulated at48 hours following treatment with Et-743 in at least 6 of 8 sarcoma cell lines	376	1.8589014683344	1	0.537952127659574	0.844873097171002	J01AA.profile.ud50
et743_sarcoma_72hrs_up	15897246	Up-regulated at48 hours following treatment with Et-743 in at least 6 of 8 sarcoma cell lines	106	0.524052009690018	0	0	1	J01AA.profile.ud50
et743_sarcoma_dn	15897246	Down-regulated following treatment with Et-743 at any timepoint in at least 8 of 11 sarcoma cell lines	459	2.26924407969546	1	0.440675381263617	0.897189940926937	J01AA.profile.ud50
et743_sarcoma_resist_dn	15897246	Constiutively down-regulated in three sarcoma cell lines resistant to Et-743 compared to six sensitive lines	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
et743_sarcoma_resist_up	15897246	Constiutively up-regulated in three sarcoma cell lines resistant to Et-743 compared to six sensitive lines	22	0.108765511445098	0	0	1	J01AA.profile.ud50
et743_sarcoma_up	15897246	Up-regulated following treatment with Et-743 at any timepoint in at least 8 of 11 sarcoma cell lines	111	0.548771444109359	1	1.82225225225225	0.42312660949506	J01AA.profile.ud50
fsh_granulosa_dn	15026540	Down-regulated in human granulosa cells stimulated with follicle stimulation hormone (FSH)	191	0.944282394818807	0	0	1	J01AA.profile.ud50
fsh_granulosa_up	15026540	Up-regulated in human granulosa cells stimulated with follicle stimulation hormone (FSH)	163	0.8058535620705	3	3.72276073619632	0.0478381379297886	J01AA.profile.ud50
fsh_human_granulosa_dn	12832290	Down-regulated by FSH in primary human granulosa cells (rFSH-17)	7	0.0346072081870767	1	28.8957142857143	0.0340981343215848	J01AA.profile.ud50
fsh_human_granulosa_up	12832290	Up-regulated by FSH in primary human granulosa cells (rFSH-17)	31	0.153260493399911	0	0	1	J01AA.profile.ud50
fsh_ovary_mcv152_dn	15386376	Down-regulated in ovarian epithelial cells (MCV152) 72 hours following FSH treatment, compared to untreated	111	0.548771444109359	0	0	1	J01AA.profile.ud50
fsh_ovary_mcv152_up	15386376	Up-regulated in ovarian epithelial cells (MCV152) 72 hours following FSH treatment, compared to untreated	120	0.593266426064172	0	0	1	J01AA.profile.ud50
fsh_rat_granulosa_dn	12832290	Down-regulated by FSH in immortalized rat granulosa cells (rFSH-17)	11	0.0543827557225491	1	18.3881818181818	0.0530581873347243	J01AA.profile.ud50
fsh_rat_granulosa_up	12832290	Up-regulated by FSH in immortalized rat granulosa cells (rFSH-17)	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
gamma_esr_old_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of fibroblasts from elderly donors with gamma radiation	49	0.242250457309537	0	0	1	J01AA.profile.ud50
gamma_esr_ws_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of Werner syndrome fibroblasts with gamma radiation	52	0.257082117961141	0	0	1	J01AA.profile.ud50
gamma_unique_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with gamma radiation, but not by UV lght or 4-NQO	120	0.593266426064172	2	3.37116666666667	0.119357212502698	J01AA.profile.ud50
gamma_unique_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with gamma radiation, but not by UV lght or 4-NQO	27	0.133484945864439	0	0	1	J01AA.profile.ud50
gamma-uv_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with UV light or gamma radiation, but not by 4-NQO	78	0.385623176941712	0	0	1	J01AA.profile.ud50
gamma-uv_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with UV light or gamma radiation, but not by 4-NQO	57	0.281801552380482	0	0	1	J01AA.profile.ud50
genotoxins_24hrs_discr	15120960	Group of genes whose regulation pattern significantly discriminates between direct (cisplatin, methyl methanesulfonate, mitomycin C) and indirect (taxol, hydroxyurea, etoposide) genotoxins, 24 hours following treatment of mouse lymphocytes (TK 3.7.2C)	69	0.341128194986899	0	0	1	J01AA.profile.ud50
genotoxins_4hrs_discr	15120960	Group of genes whose regulation pattern significantly discriminates between direct (cisplatin, methyl methanesulfonate, mitomycin C) and indirect (taxol, hydroxyurea, etoposide) genotoxins, 4 hours following treatment of mouse lymphocytes (TK 3.7.2C)	58	0.28674543926435	0	0	1	J01AA.profile.ud50
genotoxins_all_24hrs_reg	15120960	Genes most consistently regulated in mouse lymphocytes (TK 3.7.2C) at 24 hours by all six genotoxins tested (cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide)	49	0.242250457309537	0	0	1	J01AA.profile.ud50
genotoxins_all_4hrs_reg	15120960	Genes regulated in mouse lymphocytes (TK 3.7.2C) at 4 hours by all six genotoxins tested (cisplatin, methyl methanesulfonate, mitomycin C, taxol, hydroxyurea and etoposide)	45	0.222474909774064	0	0	1	J01AA.profile.ud50
gh_autocrine_dn	15845533	Down-regulated following stable autocrine expression of human growth hormone in mammary carcinoma cells (MCF-7)	189	0.93439462105107	1	1.07021164021164	0.608085679359619	J01AA.profile.ud50
gh_autocrine_up	15845533	Up-regulated following stable autocrine expression of human growth hormone in mammary carcinoma cells (MCF-7)	227	1.12226232263806	1	0.891057268722467	0.675362358894351	J01AA.profile.ud50
gh_exogenous_all_up	15845533	Up-regulated consistently at all time points (1-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	66	0.326296534335294	2	6.12939393939394	0.0425614103316015	J01AA.profile.ud50
gh_exogenous_any_dn	15845533	Down-regulated at any time point (1-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	142	0.70203193750927	3	4.27330985915493	0.0339961330891092	J01AA.profile.ud50
gh_exogenous_any_up	15845533	Up-regulated at any time point (1-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	305	1.50788549957977	4	2.65272131147541	0.0661679001802865	J01AA.profile.ud50
gh_exogenous_early_dn	15845533	Down-regulated at early time points (1-4 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	14	0.0692144163741534	2	28.8957142857143	0.00213802371025578	J01AA.profile.ud50
gh_exogenous_early_up	15845533	Up-regulated at early time points (1-4 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	31	0.153260493399911	0	0	1	J01AA.profile.ud50
gh_exogenous_late_dn	15845533	Down-regulated at late time points (12-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	123	0.608098086715776	1	1.64447154471545	0.456435140925951	J01AA.profile.ud50
gh_exogenous_late_up	15845533	Up-regulated at late time points (12-24 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	67	0.331240421219163	1	3.0189552238806	0.282557115198203	J01AA.profile.ud50
gh_exogenous_middle_dn	15845533	Down-regulated at middle time points (6-8 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
gh_exogenous_middle_up	15845533	Up-regulated at middle time points (6-8 hours) following treatment of mammary carcinoma cells (MCF-7) with exogenous human growth hormone	141	0.697088050625402	1	1.4345390070922	0.50282684512696	J01AA.profile.ud50
gh_ghrhr_ko_24hrs_dn	16464905	Down-regulated at least 2-fold 24 hours following injection of human growth hormone (GH) into mice lacking functional GHRHR (lit/lit), and with no detectable endogenous GH	277	1.36945666683146	3	2.19064981949458	0.158796648359445	J01AA.profile.ud50
gh_ghrhr_ko_24hrs_up	16464905	Up-regulated at least 2-fold 24 hours following injection of human growth hormone (GH) into mice lacking functional GHRHR (lit/lit), and with no detectable endogenous GH	187	0.924506847283334	3	3.24497326203209	0.0664995991321429	J01AA.profile.ud50
gh_ghrhr_ko_6hrs_dn	16464905	Down-regulated at least 2-fold 6 hours following injection of human growth hormone (GH) into mice lacking functional GHRHR (lit/lit), and with no detectable endogenous GH	58	0.28674543926435	0	0	1	J01AA.profile.ud50
gh_ghrhr_ko_6hrs_up	16464905	Up-regulated at least 2-fold 6 hours following injection of human growth hormone (GH) into mice lacking functional GHRHR (lit/lit), and with no detectable endogenous GH	108	0.533939783457755	3	5.61861111111111	0.0167888439347049	J01AA.profile.ud50
gh_hypophysectomy_rat_dn	11416039	Down-regulated in liver, heart or kidney tissue following treatment of hypophysectomized rats with growth hormone	29	0.143372719632175	0	0	1	J01AA.profile.ud50
gh_hypophysectomy_rat_up	11416039	Up-regulated in liver, heart or kidney tissue following treatment of hypophysectomized rats with growth hormone	39	0.192811588470856	0	0	1	J01AA.profile.ud50
gh_igf_chondrocytes_up	11416039	Up-regulated in cultured human chondrocytes by both GH and IGF-1	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
gn_camp_granulosa_dn	15026540	Down-regulated in human granulosa cells by the gonadotropins LH and FSH, as well as by cAMP-stimulator forskolin	135	0.667424729322193	0	0	1	J01AA.profile.ud50
gn_camp_granulosa_up	15026540	Up-regulated in human granulosa cells by the gonadotropins LH and FSH, as well as by cAMP-stimulator forskolin	99	0.489444801502942	3	6.12939393939394	0.013325533309291	J01AA.profile.ud50
h2o2_csbcombined	12606941	Upregulated by H2O2 in CSB-rescued fibroblasts, but deficient induction in CSB-null (Table 3)	26	0.128541058980571	0	0	1	J01AA.profile.ud50
h2o2_csbdiff_c1	12606941	Stronger induction by H2O2 in CSB-null fibroblasts, compared to CSB-rescued (Table 2, cluster 1)	58	0.28674543926435	0	0	1	J01AA.profile.ud50
h2o2_csbdiff_c2	12606941	Deficient induction by H2O2 in CSB-null fibroblasts, compared to CSB-rescued (Table 2, cluster 2)	63	0.31146487368369	0	0	1	J01AA.profile.ud50
h2o2_csbdiff_c3	12606941	Deficient induction by H2O2 in CSB-null fibroblasts, compared to CSB-rescued (Table 2, cluster 3)	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
h2o2_csbrescued_c1_up	12606941	Upregulated by H2O2 in CSB-rescued fibroblasts (Table 1, cluster 1)	84	0.41528649824492	0	0	1	J01AA.profile.ud50
h2o2_csbrescued_c2_up	12606941	Upregulated by H2O2 in CSB-rescued fibroblasts (Table 1, cluster 2)	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
h2o2_csbrescued_up	12606941	Upregulated by H2O2 in CSB-rescued fibroblasts (Table 1)	101	0.499332575270678	0	0	1	J01AA.profile.ud50
hbx_hcc_dn	11439330	Downregulated by expression of Hepatitis B virus HBx protein in SK-Hep-1 hepatocellular carcinoma cells (Fig. 3B+D)	47	0.232362683541801	0	0	1	J01AA.profile.ud50
hbx_hcc_up	11439330	Upregulated by expression of Hepatitis B virus HBx protein in SK-Hep-1 hepatocellular carcinoma cells (Fig. 3A+C)	20	0.098877737677362	0	0	1	J01AA.profile.ud50
hbx_hep_dn	11439330	Downregulated both by expression of Hepatitis B virus HBx protein in normal hepatoctyes and by HBV infection in liver samples with chronic active hepatitis	30	0.148316606516043	0	0	1	J01AA.profile.ud50
hbx_hep_up	11439330	Upregulated both by expression of Hepatitis B virus HBx protein in normal hepatoctyes and by HBV infection in liver samples with chronic active hepatitis	33	0.163148267167647	0	0	1	J01AA.profile.ud50
hbx_nl_dn	11439330	Downregulated by expression of Hepatitis B virus HBx protein in normal hepatocytes (Hhep) (Fig. 3B+C)	27	0.133484945864439	0	0	1	J01AA.profile.ud50
hbx_nl_up	11439330	Upregulated by expression of Hepatitis B virus HBx protein in normal hepatocytes (Hhep) (Fig. 3A+D)	40	0.197755475354724	0	0	1	J01AA.profile.ud50
hdaci_colon_but12hrs_dn	10969808	Downregulated by butyrate at 12 hrs in SW260 colon carcinoma cells	109	0.538883670341623	1	1.8556880733945	0.417380035500907	J01AA.profile.ud50
hdaci_colon_but12hrs_up	10969808	Upregulated by butyrate at 12 hrs in SW260 colon carcinoma cells	54	0.266969891728877	0	0	1	J01AA.profile.ud50
hdaci_colon_but16hrs_dn	10969808	Downregulated by butyrate at 16 hrs in SW260 colon carcinoma cells	167	0.825629109605972	1	1.21119760479042	0.562936493125841	J01AA.profile.ud50
hdaci_colon_but16hrs_up	10969808	Upregulated by butyrate at 16 hrs in SW260 colon carcinoma cells	47	0.232362683541801	0	0	1	J01AA.profile.ud50
hdaci_colon_but24hrs_dn	10969808	Downregulated by butyrate at 24 hrs in SW260 colon carcinoma cells	168	0.83057299648984	1	1.2039880952381	0.565097285664894	J01AA.profile.ud50
hdaci_colon_but24hrs_up	10969808	Upregulated by butyrate at 24 hrs in SW260 colon carcinoma cells	95	0.469669253967469	0	0	1	J01AA.profile.ud50
hdaci_colon_but2hrs_dn	10969808	Downregulated by butyrate at 2 hrs in SW260 colon carcinoma cells	23	0.113709398328966	0	0	1	J01AA.profile.ud50
hdaci_colon_but2hrs_up	10969808	Upregulated by butyrate at 2 hrs in SW260 colon carcinoma cells	87	0.430118158896524	0	0	1	J01AA.profile.ud50
hdaci_colon_but30min_dn	10969808	Downregulated by butyrate at 30 min in SW260 colon carcinoma cells	79	0.39056706382558	1	2.56037974683544	0.323982095569325	J01AA.profile.ud50
hdaci_colon_but48hrs_dn	10969808	Downregulated by butyrate at 48 hrs in SW260 colon carcinoma cells	165	0.815741335838236	1	1.22587878787879	0.558582647336217	J01AA.profile.ud50
hdaci_colon_but48hrs_up	10969808	Upregulated by butyrate at 48 hrs in SW260 colon carcinoma cells	135	0.667424729322193	0	0	1	J01AA.profile.ud50
hdaci_colon_but_dn	10969808	Downregulated by butyrate at any timepoint up to 48 hrs in SW260 colon carcinoma cells	387	1.91328422405695	2	1.04532299741602	0.570653358728185	J01AA.profile.ud50
hdaci_colon_but_up	10969808	Upregulated by butyrate at any timepoint up to 48 hrs in SW260 colon carcinoma cells	233	1.15192564394127	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster1	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 1)	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster10	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 10, associated with histone hyperAc)	60	0.296633213032086	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster2	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 2)	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster3	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 3)	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster4	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 4)	19	0.0939338507934939	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster5	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 5)	32	0.158204380283779	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster6	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 6)	63	0.31146487368369	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster7	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 7)	21	0.10382162456123	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster8	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 8)	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
hdaci_colon_cluster9	10969808	Regulated by TSA, butyrate and/or curcumin in SW260 colon carcinoma cells (Cluster 9, associated with histone hyperAc)	78	0.385623176941712	0	0	1	J01AA.profile.ud50
hdaci_colon_cur12hrs_dn	10969808	Downregulated by curcumin at 12 hrs in SW260 colon carcinoma cells	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
hdaci_colon_cur12hrs_up	10969808	Upregulated by curcumin at 12 hrs in SW260 colon carcinoma cells	22	0.108765511445098	0	0	1	J01AA.profile.ud50
hdaci_colon_cur16hrs_dn	10969808	Downregulated by curcumin at 16 hrs in SW260 colon carcinoma cells	22	0.108765511445098	0	0	1	J01AA.profile.ud50
hdaci_colon_cur16hrs_up	10969808	Upregulated by curcumin at 16 hrs in SW260 colon carcinoma cells	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
hdaci_colon_cur24hrs_dn	10969808	Downregulated by curcumin at 24 hrs in SW260 colon carcinoma cells	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
hdaci_colon_cur24hrs_up	10969808	Upregulated by curcumin at 24 hrs in SW260 colon carcinoma cells	73	0.360903742522371	0	0	1	J01AA.profile.ud50
hdaci_colon_cur2hrs_up	10969808	Upregulated by curcumin at 2 hrs in SW260 colon carcinoma cells	49	0.242250457309537	0	0	1	J01AA.profile.ud50
hdaci_colon_cur30min_dn	10969808	Downregulated by curcumin at 30 min in SW260 colon carcinoma cells	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
hdaci_colon_cur30min_up	10969808	Upregulated by curcumin at 30 min in SW260 colon carcinoma cells	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
hdaci_colon_cur48hrs_up	10969808	Upregulated by curcumin at 48 hrs in SW260 colon carcinoma cells	109	0.538883670341623	0	0	1	J01AA.profile.ud50
hdaci_colon_cur_dn	10969808	Downregulated by curcumin at any timepoint up to 48 hrs in SW260 colon carcinoma cells	51	0.252138231077273	0	0	1	J01AA.profile.ud50
hdaci_colon_cursul_dn	10969808	Downregulated by both curcumin and sulindac at any timepoint up to 48 hrs in SW260 colon carcinoma cells	20	0.098877737677362	0	0	1	J01AA.profile.ud50
hdaci_colon_cursul_up	10969808	Upregulated by both curcumin and sulindac at any timepoint up to 48 hrs in SW260 colon carcinoma cells	53	0.262026004845009	0	0	1	J01AA.profile.ud50
hdaci_colon_cur_up	10969808	Upregulated by curcumin at any timepoint up to 48 hrs in SW260 colon carcinoma cells	174	0.860236317793049	0	0	1	J01AA.profile.ud50
hdaci_colon_sul12hrs_dn	10969808	Downregulated by sulindac at 12 hrs in SW260 colon carcinoma cells	49	0.242250457309537	1	4.12795918367347	0.215611831112334	J01AA.profile.ud50
hdaci_colon_sul12hrs_up	10969808	Upregulated by sulindac at 12 hrs in SW260 colon carcinoma cells	40	0.197755475354724	0	0	1	J01AA.profile.ud50
hdaci_colon_sul16hrs_dn	10969808	Downregulated by sulindac at 16 hrs in SW260 colon carcinoma cells	111	0.548771444109359	2	3.6445045045045	0.104982095429141	J01AA.profile.ud50
hdaci_colon_sul16hrs_up	10969808	Upregulated by sulindac at 16 hrs in SW260 colon carcinoma cells	67	0.331240421219163	0	0	1	J01AA.profile.ud50
hdaci_colon_sul24hrs_dn	10969808	Downregulated by sulindac at 24 hrs in SW260 colon carcinoma cells	191	0.944282394818807	2	2.11801047120419	0.243703089811773	J01AA.profile.ud50
hdaci_colon_sul24hrs_up	10969808	Upregulated by sulindac at 24 hrs in SW260 colon carcinoma cells	102	0.504276462154546	0	0	1	J01AA.profile.ud50
hdaci_colon_sul2hrs_dn	10969808	Downregulated by sulindac at 2 hrs in SW260 colon carcinoma cells	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
hdaci_colon_sul2hrs_up	10969808	Upregulated by sulindac at 2 hrs in SW260 colon carcinoma cells	10	0.049438868838681	0	0	1	J01AA.profile.ud50
hdaci_colon_sul30min_dn	10969808	Downregulated by sulindac at 30 min in SW260 colon carcinoma cells	79	0.39056706382558	1	2.56037974683544	0.323982095569325	J01AA.profile.ud50
hdaci_colon_sul48hrs_dn	10969808	Downregulated by sulindac at 48 hrs in SW260 colon carcinoma cells	95	0.469669253967469	1	2.12915789473684	0.375518822884975	J01AA.profile.ud50
hdaci_colon_sul48hrs_up	10969808	Upregulated by sulindac at 48 hrs in SW260 colon carcinoma cells	140	0.692144163741534	0	0	1	J01AA.profile.ud50
hdaci_colon_sul_dn	10969808	Downregulated by sulindac at any timepoint up to 48 hrs in SW260 colon carcinoma cells	340	1.68092154051515	3	1.78473529411765	0.237540286952648	J01AA.profile.ud50
hdaci_colon_sul_up	10969808	Upregulated by sulindac at any timepoint up to 48 hrs in SW260 colon carcinoma cells	192	0.949226281702675	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa12hrs_dn	10969808	Downregulated by TSA at 12 hrs in SW260 colon carcinoma cells	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa12hrs_up	10969808	Upregulated by TSA at 12 hrs in SW260 colon carcinoma cells	21	0.10382162456123	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa24hrs_dn	10969808	Downregulated by TSA at 24 hrs in SW260 colon carcinoma cells	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa24hrs_up	10969808	Upregulated by TSA at 24 hrs in SW260 colon carcinoma cells	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa2hrs_dn	10969808	Downregulated by TSA at 2 hrs in SW260 colon carcinoma cells	33	0.163148267167647	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa2hrs_up	10969808	Upregulated by TSA at 2 hrs in SW260 colon carcinoma cells	61	0.301577099915954	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa30min_dn	10969808	Downregulated by TSA at 30 min in SW260 colon carcinoma cells	34	0.168092154051515	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa48hrs_dn	10969808	Downregulated by TSA at 48 hrs in SW260 colon carcinoma cells	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa48hrs_up	10969808	Upregulated by TSA at 48 hrs in SW260 colon carcinoma cells	43	0.212587136006328	0	0	1	J01AA.profile.ud50
hdaci_colon_tsabut_dn	10969808	Downregulated by both butyrate and TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells	46	0.227418796657932	0	0	1	J01AA.profile.ud50
hdaci_colon_tsabut_up	10969808	Upregulated by both butyrate and TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells	79	0.39056706382558	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa_dn	10969808	Downregulated by TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells	109	0.538883670341623	0	0	1	J01AA.profile.ud50
hdaci_colon_tsa_up	10969808	Upregulated by TSA at any timepoint up to 48 hrs in SW260 colon carcinoma cells	122	0.603154199831908	0	0	1	J01AA.profile.ud50
hdaci_three_dn	12589032	Downregulated in several cell lines by all of TSA, SAHA, and MS-275	10	0.049438868838681	0	0	1	J01AA.profile.ud50
hdaci_three_up	12589032	Upregulated in several cell lines by all of TSA, SAHA, and MS-275	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
heartfailure_atria_dn	15103417	Downregulated in the atria of failing hearts (DCM and ICM) compared to healthy controls	213	1.0530479062639	2	1.89924882629108	0.283795077015192	J01AA.profile.ud50
heartfailure_atria_up	15103417	Upregulated in atria of failing hearts (DCM and ICM) compared to healthy controls	58	0.28674543926435	0	0	1	J01AA.profile.ud50
heartfailure_ventricles_dn	15103417	Downregulated in the ventricles of failing hearts (DCM and ICM) compared to healthy controls	120	0.593266426064172	0	0	1	J01AA.profile.ud50
heartfailure_ventricles_up	15103417	Upregulated in the ventricles of failing hearts (DCM and ICM) compared to healthy controls	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
heat_glioblastoma_dn	16802863	Down-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG).	32	0.158204380283779	0	0	1	J01AA.profile.ud50
heat_glioblastoma_up	16802863	Up-regulated following 1 hr 43degC heat shock in human glioblastoma cells (U87MG).	78	0.385623176941712	1	2.59320512820513	0.320623334181982	J01AA.profile.ud50
heatshock_hela_2hr_dn	17216044	Down-regulated at 2 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05).	223	1.10248677510259	3	2.72112107623318	0.0996351660355207	J01AA.profile.ud50
heatshock_hela_2hr_up	17216044	Up-regulated at 2 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05).	177	0.875067978444653	2	2.28553672316384	0.218294585258786	J01AA.profile.ud50
heatshock_hela_30min_dn	17216044	Down-regulated at 30 minutes following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05).	67	0.331240421219163	0	0	1	J01AA.profile.ud50
heatshock_hela_30min_up	17216044	Up-regulated at 30 minutes following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, p < 0.05).	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
heatshock_hela_4hr_dn	17216044	Down-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05).	1829	9.04236911059475	11	1.21649535265172	0.298764177100751	J01AA.profile.ud50
heatshock_hela_4hr_up	17216044	Up-regulated at 4 hours following 1.5 hr 43degC heat shock of HeLa cells compared to untreated controls (> 1.5-fold, FDR < 0.05).	675	3.33712364661097	6	1.79795555555556	0.12112548978595	J01AA.profile.ud50
heatshock_old_dn	12618007	Downregulated after heat shock in lymphocytes from old individuals, compared to young	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
heatshock_old_up	12618007	Upregulated after heat shock in lymphocytes from old individuals, compared to young	27	0.133484945864439	0	0	1	J01AA.profile.ud50
heatshock_young_dn	12618007	Downregulated after heat shock in lymphocytes from young individuals, compared to old	10	0.049438868838681	0	0	1	J01AA.profile.ud50
heatshock_young_up	12618007	Upregulated after heat shock in lymphocytes from young individuals, compared to old	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
hematop_stem_all_up	15231652	Up-regulated in populations of human hematopoietic stem cells (CD34+/CD38-/Lin-) from bone marrow, umbilical cord blood, and peripheral blood stem-progenitor cells, compared to the stem cell-depleted population (CD34+/[CD38/Lin++])	52	0.257082117961141	0	0	1	J01AA.profile.ud50
hg_progeria_dn	10741968	Downregulated in fibroblasts from patients with Hutchinson-Gilford progeria, compared to normal young individuals	48	0.237306570425669	0	0	1	J01AA.profile.ud50
hg_progeria_up	10741968	regulated in fibroblasts from patients with Hutchinson-Gilford progeria, compared to normal young individuals	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
hif1_targets	11516994	Hif-1 (hypoxia-inducible factor 1) transcripional targets	67	0.331240421219163	0	0	1	J01AA.profile.ud50
hippocampus_development_neonatal	11438693	Highly expressed in neonatal mouse hippocampus (clusters 4 and 8)	51	0.252138231077273	0	0	1	J01AA.profile.ud50
hippocampus_development_postnatal	11438693	Highly expressed in late postnatal mouse hippocampus (clusters 11 and 15)	79	0.39056706382558	0	0	1	J01AA.profile.ud50
hippocampus_development_prenatal	11438693	Highly expressed in prenatal mouse hippocampus (cluster 1)	58	0.28674543926435	0	0	1	J01AA.profile.ud50
hpv31_dn	10756030	Downregulated in normal human keratinocytes carrying episomal HPV31 DNA	82	0.405398724477184	0	0	1	J01AA.profile.ud50
hpv31_up	10756030	Upregulated in normal human keratinocytes carrying episomal HPV31 DNA	69	0.341128194986899	1	2.93144927536232	0.289633492382835	J01AA.profile.ud50
hpve7_hpve6_hfk_dn	14517073	Down-regulated in human foreskin keratinocytes expressing both HPV E6 and E7 proteins compared to E7 expression only	39	0.192811588470856	0	0	1	J01AA.profile.ud50
hpve7_hpve6_hfk_up	14517073	Up-regulated in human foreskin keratinocytes expressing both HPV E6 and E7 proteins compared to E7 expression only	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
hpv_high-risk_up	17309674	Up-regulated in both HPV16- and HPV18-positive cervical tumors compared to normal cervial tissue.	21	0.10382162456123	0	0	1	J01AA.profile.ud50
hpv_hnscc_up	16467079	Up-regulated in HPV-positive head and neck squamous cell carcinomas (HNSCC) compared to HPV-negative HNSCC.	68	0.336184308103031	0	0	1	J01AA.profile.ud50
hsc_earlyprogenitors_adult	12228721	Up-regulated in mouse hematopoietic early progenitors from adult bone marrow (Early Progenitors Shared + Adult)	526	2.60048450091462	6	2.30726235741445	0.0486355208825999	J01AA.profile.ud50
hsc_earlyprogenitors_fetal	12228721	Up-regulated in mouse hematopoietic early progenitors from fetal liver (Early Progenitors Shared)	520	2.57082117961141	5	1.94490384615385	0.117988971655353	J01AA.profile.ud50
hsc_earlyprogenitors_shared	12228721	Up-regulated in mouse hematopoietic early progenitors from both adult bone marrow and fetal liver (Cluster iv, Early Progenitors Shared)	520	2.57082117961141	5	1.94490384615385	0.117988971655353	J01AA.profile.ud50
hsc_hsc_adult	12228721	Up-regulated in mouse hematopoietic stem cells from adult bone marrow (HSC Shared + Adult)	363	1.79463093884412	1	0.557217630853994	0.834549271407385	J01AA.profile.ud50
hsc_hscandprogenitors_adult	12228721	Up-regulated in mouse hematopoietic stem cells and progenitors from adult bone marrow (HSC and Progenitors Shared + Adult)	724	3.5793741039205	2	0.558756906077348	0.872904065589795	J01AA.profile.ud50
hsc_hscandprogenitors_fetal	12228721	Up-regulated in mouse hematopoietic stem cells and progenitors from fetal liver (HSC and Progenitors Shared)	717	3.54476689573343	2	0.564211994421199	0.869412812540576	J01AA.profile.ud50
hsc_hscandprogenitors_shared	12228721	Up-regulated in mouse hematopoietic stem cells and progenitors from both adult bone marrow and fetal liver (Cluster iii, HSC and Progenitors Shared)	717	3.54476689573343	2	0.564211994421199	0.869412812540576	J01AA.profile.ud50
hsc_hsc_fetal	12228721	Up-regulated in mouse hematopoietic stem cells from fetal liver (HSC Shared + Fetal)	303	1.49799772581203	1	0.667557755775578	0.777251721620168	J01AA.profile.ud50
hsc_hsc_shared	12228721	Up-regulated in mouse hematopoietic stem cells from both adult bone marrow and fetal liver (Cluster ii, HSC Shared)	270	1.33484945864439	1	0.749148148148148	0.737672104185749	J01AA.profile.ud50
hsc_intermediateprogenitors_adult	12228721	Up-regulated in mouse hematopoietic intermediate progenitors from adult bone marrow (Intermediate Progenitors Shared + Adult)	161	0.795965788302764	0	0	1	J01AA.profile.ud50
hsc_intermediateprogenitors_fetal	12228721	Up-regulated in mouse hematopoietic intermediate progenitors from fetal liver (Intermediate Progenitors Shared + Fetal)	167	0.825629109605972	0	0	1	J01AA.profile.ud50
hsc_intermediateprogenitors_shared	12228721	Up-regulated in mouse hematopoietic intermediate progenitors from both adult bone marrow and fetal liver (Cluster v, Intermediate Progenitors Shared)	151	0.746526919464083	0	0	1	J01AA.profile.ud50
hsc_lateprogenitors_adult	12228721	Up-regulated in mouse hematopoietic late progenitors from adult bone marrow (Late Progenitors Shared + Adult)	558	2.7586888811984	2	0.724982078853047	0.762555319918109	J01AA.profile.ud50
hsc_lateprogenitors_fetal	12228721	Up-regulated in mouse hematopoietic late progenitors from fetal liver (Late Progenitors Shared + Fetal)	558	2.7586888811984	2	0.724982078853047	0.762555319918109	J01AA.profile.ud50
hsc_lateprogenitors_shared	12228721	Up-regulated in mouse hematopoietic late progenitors from both adult bone marrow and fetal liver (Cluster vi, Late Progenitors Shared)	549	2.71419389924359	2	0.736867030965392	0.754667188835372	J01AA.profile.ud50
hsc_lthsc_adult	12228721	Up-regulated in mouse long-term functional hematopoietic stem cells from adult bone marrow (LT-HSC Shared + Adult)	385	1.90339645028922	3	1.57612987012987	0.297131369884062	J01AA.profile.ud50
hsc_lthsc_fetal	12228721	Up-regulated in mouse long-term functional hematopoietic stem cells from fetal liver (LT-HSC Shared)	272	1.34473723241212	1	0.743639705882353	0.7402595312495	J01AA.profile.ud50
hsc_lthsc_shared	12228721	Up-regulated in mouse long-term functional hematopoietic stem cells from both adult bone marrow and fetal liver (Cluster i, LT-HSC Shared)	272	1.34473723241212	1	0.743639705882353	0.7402595312495	J01AA.profile.ud50
hsc_mature_adult	12228721	Up-regulated in mouse mature bood cells from adult bone marrow, compared to hematopoietic progenitors (Cluster vii, Mature Blood Cells Shared + Adult)	427	2.11103969941168	1	0.473700234192037	0.879520460064675	J01AA.profile.ud50
hsc_mature_fetal	12228721	Up-regulated in mouse mature bood cells from fetal liver, compared to hematopoietic progenitors (Mature Blood Cells Shared + Fetal)	376	1.8589014683344	1	0.537952127659574	0.844873097171002	J01AA.profile.ud50
hsc_mature_shared	12228721	Up-regulated in mouse mature bood cells from both adult bone marrow and fetal liver, compared to hematopoietic progenitors (Cluster vii, Mature Blood Cells Shared)	309	1.52766104711524	1	0.654595469255663	0.783778045451167	J01AA.profile.ud50
hsc_sthsc_adult	12228721	Up-regulated in mouse short-term functional hematopoietic stem cells from adult bone marrow (ST-HSC Shared + Adult)	51	0.252138231077273	0	0	1	J01AA.profile.ud50
hsc_sthsc_fetal	12228721	Up-regulated in mouse short-term functional hematopoietic stem cells from fetal liver (ST-HSC Shared)	44	0.217531022890196	0	0	1	J01AA.profile.ud50
hsc_sthsc_shared	12228721	Up-regulated in mouse short-term functional hematopoietic stem cells from both adult bone marrow and fetal liver (ST-HSC Shared)	44	0.217531022890196	0	0	1	J01AA.profile.ud50
htert_dn	12702554	Downregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls	112	0.553715330993227	0	0	1	J01AA.profile.ud50
htert_up	12702554	Upregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls	97	0.479557027735205	0	0	1	J01AA.profile.ud50
human_tissue_cerebellum	11904358	Genes expressed specifically in human cerebellum tissue	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
human_tissue_heart	11904358	Genes expressed specifically in human heart tissue	19	0.0939338507934939	1	10.6457894736842	0.089869076753069	J01AA.profile.ud50
human_tissue_kidney	11904358	Genes expressed specifically in human kidney tissue	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
human_tissue_liver	11904358	Genes expressed specifically in human liver tissue	55	0.271913778612745	0	0	1	J01AA.profile.ud50
human_tissue_lung	11904358	Genes expressed specifically in human lung tissue	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
human_tissue_pancreas	11904358	Genes expressed specifically in human pancreas tissue	71	0.351015968754635	0	0	1	J01AA.profile.ud50
human_tissue_pituitary	11904358	Genes expressed specifically in human pituitary gland tissue	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
human_tissue_placenta	11904358	Genes expressed specifically in human placental tissue	40	0.197755475354724	0	0	1	J01AA.profile.ud50
human_tissue_prostate	11904358	Genes expressed specifically in human prostate tissue	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
human_tissue_salivary	11904358	Genes expressed specifically in human salivary gland tissue	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
human_tissue_spleen	11904358	Genes expressed specifically in human spleen tissue	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
human_tissue_testis	11904358	Genes expressed specifically in human testis tissue	122	0.603154199831908	1	1.65795081967213	0.453734465916889	J01AA.profile.ud50
human_tissue_thymus	11904358	Genes expressed specifically in human thymus tissue	21	0.10382162456123	0	0	1	J01AA.profile.ud50
human_tissue_trachea	11904358	Genes expressed specifically in human tracheal tissue	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
hyperme_colonca_sw48	16007088	Gene identified by chromatin IP and CpG island microarray as being hypermethylated in SW48 colon cancer cells, versus normal colon murcosa or WI38 fibroblasts	20	0.098877737677362	1	10.1135	0.0943686610871122	J01AA.profile.ud50
hyperthyroid_rat_neuron_up	15234464	Up-regulated in cerebral tissue from hyperthyroid rats, compared to euthyroid controls	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
hypophysectomy_rat_dn	11416039	Down-regulated in liver, heart or kidney tissue from hypophysectomized rats (lacking growth hormone), compared to normal controls	95	0.469669253967469	0	0	1	J01AA.profile.ud50
hypophysectomy_rat_up	11416039	Up-regulated in liver, heart or kidney tissue from hypophysectomized rats (lacking growth hormone), compared to normal controls	59	0.291689326148218	1	3.42830508474576	0.253539629887189	J01AA.profile.ud50
hypoxia_fibro_up	14499499	Upregulated by hypoxia in normal fibroblasts from both young and old donors (Table 3)	34	0.168092154051515	0	0	1	J01AA.profile.ud50
hypoxia_fibro_young_up	14499499	Upregulated by hypoxia in normal fibroblasts from young, but not old, donors (Table 1)	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
hypoxia_normal_up	12692265	Upregulated by hypoxia in normal, RPTEC renal cells (Fig. 3)	376	1.8589014683344	0	0	1	J01AA.profile.ud50
hypoxia_rcc_novhl_up	12692265	Upregulated by hypoxia in VHL-null renal carcinoma cells (Fig. 4h+i)	88	0.435062045780393	0	0	1	J01AA.profile.ud50
hypoxia_rcc_up	12692265	Upregulated by hypoxia in VHL-rescued renal carcinoma cells (Fig. 3f+g)	170	0.840460770257577	1	1.18982352941176	0.569386875415451	J01AA.profile.ud50
hypoxia_reg_up	12885785	Upregulated by hypoxia in renal cells, and downregulated with reoxygenation	80	0.395510950709448	0	0	1	J01AA.profile.ud50
hypoxia_review	11902584	Genes known to be induced by hypoxia	160	0.791021901418896	0	0	1	J01AA.profile.ud50
icf_dn	11741835	Downregulated in B-cells from ICF syndrome (DNMT3B) compared to normals	23	0.113709398328966	0	0	1	J01AA.profile.ud50
icf_up	11741835	Upregulated in B-cells from ICF syndrome (DNMT3B) compared to normals	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
idx_tsa_dn_cluster1	15033539	Down-regulated at 48-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1)	84	0.41528649824492	0	0	1	J01AA.profile.ud50
idx_tsa_dn_cluster2	15033539	Progressively down-regulated from 8-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 2)	114	0.563603104760963	1	1.77429824561404	0.431640369721972	J01AA.profile.ud50
idx_tsa_dn_cluster3	15033539	Strongly down-regulated at 8-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 3)	108	0.533939783457755	0	0	1	J01AA.profile.ud50
idx_tsa_dn_cluster4	15033539	Strongly down-regulated at 8-48 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 4)	46	0.227418796657932	1	4.39717391304348	0.203862064874593	J01AA.profile.ud50
idx_tsa_dn_cluster5	15033539	Strongly down-regulated at 2-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 5)	96	0.474613140851337	1	2.10697916666667	0.378606187185736	J01AA.profile.ud50
idx_tsa_dn_cluster6	15033539	Strongly down-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 6)	48	0.237306570425669	1	4.21395833333333	0.211714637447666	J01AA.profile.ud50
idx_tsa_up_cluster1	15033539	Strongly up-regulated at 2 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 1)	44	0.217531022890196	1	4.59704545454545	0.195931268223102	J01AA.profile.ud50
idx_tsa_up_cluster2	15033539	Strongly up-regulated at 8 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 2)	105	0.51910812280615	0	0	1	J01AA.profile.ud50
idx_tsa_up_cluster3	15033539	Strongly up-regulated at 16-24 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 3)	136	0.672368616206061	0	0	1	J01AA.profile.ud50
idx_tsa_up_cluster4	15033539	Progressively up-regulated from 8-48 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 4)	65	0.321352647451426	0	0	1	J01AA.profile.ud50
idx_tsa_up_cluster5	15033539	Up-regulated at 48-96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 5)	149	0.736639145696346	1	1.35751677852349	0.52215367786475	J01AA.profile.ud50
idx_tsa_up_cluster6	15033539	Strongly up-regulated at 96 hours during differentiation of 3T3-L1 fibroblasts into adipocytes with IDX (insulin, dexamethasone and isobutylxanthine), vs. fibroblasts treated with IDX + TSA to prevent differentiation (cluster 6)	249	1.23102783408316	1	0.812329317269076	0.708897817898008	J01AA.profile.ud50
ifna_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following treatment with interferon-alpha	103	0.509220349038414	0	0	1	J01AA.profile.ud50
ifn_all_up	9861020	Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferons alpha, beta and gamma	41	0.202699362238592	0	0	1	J01AA.profile.ud50
ifnalpha_hcc_dn	11910354	Downregulated by interferon alpha treatment in Hep3B hepatocellular carcinoma cells	22	0.108765511445098	0	0	1	J01AA.profile.ud50
ifnalpha_hcc_up	11910354	Upregulated by interferon alpha treatment in Hep3B hepatocellular carcinoma cells	50	0.247194344193405	0	0	1	J01AA.profile.ud50
ifnalpha_nl_dn	11910354	Downregulated by interferon alpha treatment in normal primary hepatocytes	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
ifnalpha_nl_hcc_dn	11910354	Downregulated by interferon alpha treatment in both primary normal hepatocytes and Hep3B hepatocellular carcinoma cells	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
ifnalpha_nl_hcc_up	11910354	Upregulated by interferon alpha treatment in both normal primary hepatocytes and Hep3B hepatocellular carcinoma cells	30	0.148316606516043	0	0	1	J01AA.profile.ud50
ifnalpha_nl_up	11910354	Upregulated by interferon alpha treatment in normal primary hepatocytes	53	0.262026004845009	1	3.81641509433962	0.231008883125008	J01AA.profile.ud50
ifnalpha_resist_dn	12414529	Down-regulated in mycosis fungoides (cutaneous T-cell lymphoma) T-cells resistant to IFN-alpha, compared to sensitive parent cell line 	25	0.123597172096702	0	0	1	J01AA.profile.ud50
ifn_alpha_up	9861020	Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferon alpha	80	0.395510950709448	0	0	1	J01AA.profile.ud50
ifn_any_up	9861020	Upregulated 2-fold in HT1080 cells 6 hours following treatment with any of interferons alpha, beta and gamma	172	0.850348544025313	0	0	1	J01AA.profile.ud50
ifna_uv-cmv_common_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following either infection with UV-inactivated CMV or interferon-alpha	47	0.232362683541801	0	0	1	J01AA.profile.ud50
ifn_beta_glioma_dn	16140920	Down-regulated in human glioma cells (T98) at 48 hours following treatment with interferon-beta	92	0.454837593315865	0	0	1	J01AA.profile.ud50
ifn_beta_glioma_up	16140920	Up-regulated in human glioma cells (T98) at 48 hours following treatment with interferon-beta	124	0.613041973599644	0	0	1	J01AA.profile.ud50
ifn_beta_up	9861020	Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferon beta	143	0.706975824393138	0	0	1	J01AA.profile.ud50
ifn_gamma_up	9861020	Upregulated 2-fold in HT1080 cells 6 hours following treatment with interferon gamma	80	0.395510950709448	0	0	1	J01AA.profile.ud50
igf1_nih3t3_up	11606465	Up-regulated by treatment with IGF1 of NIH3T3 cells overexpressing IGF1R (Tables 1+3)	61	0.301577099915954	0	0	1	J01AA.profile.ud50
igfr_ir_dn	12213819	Down-regulated in common following stimulation of chimeric TrkC/IR or TrkC/IGFR in NIH3T3 cells	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
igfr_ir_up	12213819	Up-regulated in common following stimulation of chimeric TrkC/IR or TrkC/IGFR in NIH3T3 cells	36	0.177979927819252	0	0	1	J01AA.profile.ud50
igfr_vs_ir_up	12213819	Up-regulated following stimulation of chimeric TrkC/IGFR in NIH3T3 cells, compared to stimulation of TrkC/IR	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
igf_vs_pdgf_dn	15475267	Down-regulated in mouse C2AS12 myoblasts by treatment with IGF1, compared to treatment with PDGF	53	0.262026004845009	2	7.63283018867924	0.0285120917781901	J01AA.profile.ud50
igf_vs_pdgf_up	15475267	Up-regulated in mouse C2AS12 myoblasts by treatment with IGF1, compared to treatment with PDGF	87	0.430118158896524	0	0	1	J01AA.profile.ud50
il1_cornea_dn	12091409	Downregulated in corneal fibroblasts after interleukin-1 treatment (Tables 1 and 3)	163	0.8058535620705	0	0	1	J01AA.profile.ud50
il1_cornea_up	12091409	Upregulated in corneal fibroblasts after interleukin-1 treatment (Tables 1 and 2)	136	0.672368616206061	2	2.97455882352941	0.145979145353674	J01AA.profile.ud50
il2_pbmc_24hr_dn	17471163	Down-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	646	3.19375092697879	1	0.313111455108359	0.959305885996687	J01AA.profile.ud50
il2_pbmc_24hr_up	17471163	Up-regulated at 24 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	503	2.48677510258565	3	1.20638170974155	0.453100169027261	J01AA.profile.ud50
il2_pbmc_2hr_dn	17471163	Down-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	27	0.133484945864439	1	7.49148148148148	0.125249000127201	J01AA.profile.ud50
il2_pbmc_2hr_up	17471163	Up-regulated at 2 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	66	0.326296534335294	0	0	1	J01AA.profile.ud50
il2_pbmc_30min_dn	17471163	Down-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	27	0.133484945864439	1	7.49148148148148	0.125249000127201	J01AA.profile.ud50
il2_pbmc_30min_up	17471163	Up-regulated at 30 min following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	66	0.326296534335294	0	0	1	J01AA.profile.ud50
il2_pbmc_48hr_dn	17471163	Down-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	531	2.62520393533396	3	1.14276836158192	0.488265809956799	J01AA.profile.ud50
il2_pbmc_48hr_up	17471163	Up-regulated at 48 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	511	2.5263261976566	2	0.791663405088063	0.718826125296921	J01AA.profile.ud50
il2_pbmc_4hr_dn	17471163	Down-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	555	2.74385722054679	6	2.1867027027027	0.0598558678475844	J01AA.profile.ud50
il2_pbmc_4hr_up	17471163	Up-regulated at 4 hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	510	2.52138231077273	2	0.79321568627451	0.717825845626198	J01AA.profile.ud50
il2_pbmc_6hr_dn	17471163	Down-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	530	2.62026004845009	3	1.14492452830189	0.487028651841204	J01AA.profile.ud50
il2_pbmc_6hr_up	17471163	Up-regulated at 6hr following treatment of peripheral blood mononuclear cells (PBMC) with recombinant IL-2.	530	2.62026004845009	2	0.763283018867924	0.737268623882407	J01AA.profile.ud50
il6_fibro_dn	15095275	Downregulated following IL-6 treatment in normal skin fibroblasts	10	0.049438868838681	0	0	1	J01AA.profile.ud50
il6_fibro_up	15095275	Upregulated following IL-6 treatment in normal skin fibroblasts	85	0.420230385128788	0	0	1	J01AA.profile.ud50
il6_scar_fibro_dn	15095275	Downregulated following IL-6 treatment in hypertrophic scar fibroblasts	22	0.108765511445098	0	0	1	J01AA.profile.ud50
il6_scar_fibro_up	15095275	Upregulated following IL-6 treatment in hypertrophic scar fibroblasts	44	0.217531022890196	0	0	1	J01AA.profile.ud50
innerear_up	11888886	Genes prefentially expressed in human inner ear tissue (cochlea and vestibule), at least 10-fold higher from a mixture of 29 other tissues	53	0.262026004845009	0	0	1	J01AA.profile.ud50
inos_10_dn	12381414	Ten most-downregulated genes following iNOS induction in hepatocytes	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
inos_10_up	12381414	Ten most-upregulated genes following iNOS induction in hepatocytes	10	0.049438868838681	0	0	1	J01AA.profile.ud50
inos_all_dn	12381414	Downregulated following iNOS induction in hepatocytes (Tables 3-17)	117	0.578434765412567	1	1.72880341880342	0.440028479997968	J01AA.profile.ud50
inos_all_up	12381414	Upregulated following iNOS induction in hepatocytes (Tables 3-17)	87	0.430118158896524	0	0	1	J01AA.profile.ud50
insulin_adip_insens_dn	14530283	Down-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment	25	0.123597172096702	0	0	1	J01AA.profile.ud50
insulin_adip_insens_up	14530283	Up-regulated by insulin in murine adipocytes, and continue to respond following induction of insulin-resistance with TNFalpha treatment	37	0.18292381470312	0	0	1	J01AA.profile.ud50
insulin_adip_sens_dn	14530283	Down-regulated by insulin in murine adipocytes, but response is blunted following induction of insulin-resistance with TNFalpha treatment	29	0.143372719632175	1	6.9748275862069	0.133876959437779	J01AA.profile.ud50
insulin_adip_sens_up	14530283	Up-regulated by insulin in murine adipocytes, but response is blunted following induction of insulin-resistance with TNFalpha treatment	21	0.10382162456123	0	0	1	J01AA.profile.ud50
insulin_nih3t3_up	11606465	Up-regulated by treatment with insulin of NIH3T3 cells overexpressing insulin receptor	30	0.148316606516043	0	0	1	J01AA.profile.ud50
irs1_ko_adip_dn	15895078	Down-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls	201	0.993721263657488	0	0	1	J01AA.profile.ud50
irs1_ko_adip_up	15895078	Up-regulated in brown preadipocytes from Irs1-knockout mice, which display severe defects in adipocyte differentiation, versus wild-type controls	159	0.786078014535027	0	0	1	J01AA.profile.ud50
irs_ko_adip_dn	15895078	Progressively down-regulated in brown preadipocytes from four Irs-knockout mouse lines with increasingly severe defects in adipocyte differentiation (wt, Irs4 KO, Irs2 KO, Irs3 KO, Irs1 KO)	64	0.316408760567558	0	0	1	J01AA.profile.ud50
irs_ko_adip_up	15895078	Progressively up-regulated in brown preadipocytes from four Irs-knockout mouse lines with increasingly severe defects in adipocyte differentiation (wt, Irs4 KO, Irs2 KO, Irs3 KO, Irs1 KO)	36	0.177979927819252	0	0	1	J01AA.profile.ud50
jnk_dn	12354774	Downregulated by expression of constitutively active JNK in 3T3 cells	57	0.281801552380482	0	0	1	J01AA.profile.ud50
jnk_up	12354774	Upregulated by expression of constitutively active JNK in 3T3 cells	66	0.326296534335294	0	0	1	J01AA.profile.ud50
lal_ko_1mo_up	16127159	Up-regulated at 1 month of age in lungs from lysosomal acid lipase (LAL) knockout mice, which display pulmonary pathology, versus wild-type controls	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
lal_ko_3mo_up	16127159	Up-regulated at 3 months of age in lungs from lysosomal acid lipase (LAL) knockout mice, which display pulmonary pathology, versus wild-type controls	69	0.341128194986899	0	0	1	J01AA.profile.ud50
lal_ko_6mo_up	16127159	Up-regulated at 6 months of age in lungs from lysosomal acid lipase (LAL) knockout mice, which display pulmonary pathology, versus wild-type controls	106	0.524052009690018	0	0	1	J01AA.profile.ud50
lh_granulosa_dn	15026540	Down-regulated in human granulosa cells stimulated with luteinizing hormone (LH)	191	0.944282394818807	0	0	1	J01AA.profile.ud50
lh_granulosa_up	15026540	Up-regulated in human granulosa cells stimulated with luteinizing hormone (LH)	167	0.825629109605972	3	3.63359281437126	0.0507431219185787	J01AA.profile.ud50
lvad_heartfailure_dn	12824457	Downregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device	78	0.385623176941712	0	0	1	J01AA.profile.ud50
lvad_heartfailure_up	12824457	Upregulated in the left ventricle myocardium of patients with heart failure following implantation of a left ventricular assist device	180	0.889899639096258	0	0	1	J01AA.profile.ud50
mammary_dev_up	16278680	Up-regulated in the intact developing mouse mammary gland; higher expression in 5/6 week pubertal glands than in 3 week, mid-pregnant, lactating, involuting or resuckled glands	84	0.41528649824492	1	2.40797619047619	0.340528458282614	J01AA.profile.ud50
maternalcare_tsa-met_all	14635221	Top 100 genes significantly altered in hippocampi from adult offspring of mice with high versus low maternal care, following treatment with either trichostatin, methionine or vehicle control and exposure to open-field stress. 	151	0.746526919464083	1	1.33953642384106	0.52686683466559	J01AA.profile.ud50
mbd_targets_all	14633992	Genes identified by ChIP-CpG microarray analysis as being bound by any of several methyl-CpG binding proteins (MeCP2, MBD1, MBD2, MBD3) in either of two breast cancer cell lines (MCF7 or MDA-MB-231)	24	0.118653285212834	0	0	1	J01AA.profile.ud50
mbd_targets_mbd1	14633992	Genes identified by ChIP-CpG microarray analysis as being bound by the methyl-CpG binding protein MBD1 in either of two breast cancer cell lines (MCF7 or MDA-MB-231)	10	0.049438868838681	0	0	1	J01AA.profile.ud50
mbd_targets_mbd2	14633992	Genes identified by ChIP-CpG microarray analysis as being bound by the methyl-CpG binding protein MBD2 in either of two breast cancer cell lines (MCF7 or MDA-MB-231)	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
mbd_targets_mbd3	14633992	Genes identified by ChIP-CpG microarray analysis as being bound by the methyl-CpG binding protein MBD3 in either of two breast cancer cell lines (MCF7 or MDA-MB-231)	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
mbd_targets_mecp2	14633992	Genes identified by ChIP-CpG microarray analysis as being bound by the methyl-CpG binding protein MeCP2 in either of two breast cancer cell lines (MCF7 or MDA-MB-231)	10	0.049438868838681	0	0	1	J01AA.profile.ud50
metastasis_adenocarc_dn	12469122	Down-regulated in adenocarcinoma metastases, compared to similar primary tumors; predictive of metastatic potential	97	0.479557027735205	2	4.17051546391753	0.0836845179803737	J01AA.profile.ud50
metastasis_adenocarc_up	12469122	Up-regulated in adenocarcinoma metastases, compared to similar primary tumors; predictive of metastatic potential	81	0.400454837593316	0	0	1	J01AA.profile.ud50
methotrexate_probcell_dn	12447701	Down-regulated in pro-B cells (FL5.12) following treatment with methotrexate	22	0.108765511445098	0	0	1	J01AA.profile.ud50
methotrexate_probcell_up	12447701	Up-regulated in pro-B cells (FL5.12) following treatment with methotrexate	24	0.118653285212834	0	0	1	J01AA.profile.ud50
microrna_human	15502875	Predicted human MicroRNA targets	2276	11.2522865476838	13	1.15532073813708	0.33899356334132	J01AA.profile.ud50
microrna_mammal	15502875	Predicted MicroRNA targets conserved across human, mouse and rat	1331	6.58031344242844	9	1.36771600300526	0.217630180878659	J01AA.profile.ud50
microrna_vertebrate	15502875	Predicted MicroRNA targets conserved across human, mouse, rat, zebrafish and fugu	214	1.05799179314777	0	0	1	J01AA.profile.ud50
middleage_dn	10741968	Downregulated in fibroblasts from middle-age individuals, compared to young	23	0.113709398328966	0	0	1	J01AA.profile.ud50
middleage_up	10741968	Upregulated in fibroblasts from middle-age individuals, compared to young	25	0.123597172096702	0	0	1	J01AA.profile.ud50
mkk6ee_up	12208764	Upregulated by expression of constitutively active MKK6	31	0.153260493399911	0	0	1	J01AA.profile.ud50
mmc_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to mitomycin C	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
mms_human_lymph_high_24hrs_dn	15515172	Down-regulated at 24 hours following treatment of human lymphocytes (TK6) with a high dose of methyl methanesulfonate (MMS)	30	0.148316606516043	0	0	1	J01AA.profile.ud50
mms_human_lymph_high_24hrs_up	15515172	Up-regulated at 24 hours following treatment of human lymphocytes (TK6) with a high dose of methyl methanesulfonate (MMS)	32	0.158204380283779	1	6.3209375	0.146659597735406	J01AA.profile.ud50
mms_human_lymph_high_4hrs_dn	15515172	Down-regulated at 4 hours following treatment of human lymphocytes (TK6) with a high dose of methyl methanesulfonate (MMS)	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
mms_human_lymph_low_4hrs_dn	15515172	Down-regulated at 4 hours following treatment of human lymphocytes (TK6) with a low dose of methyl methanesulfonate (MMS)	38	0.187867701586988	1	5.3228947368421	0.171661702549689	J01AA.profile.ud50
mms_mouse_lymph_high_24hrs_up	15515172	Up-regulated at 24 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a high dose of methyl methanesulfonate (MMS)	63	0.31146487368369	0	0	1	J01AA.profile.ud50
mms_mouse_lymph_high_4hrs_up	15515172	Up-regulated at 4 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a high dose of methyl methanesulfonate (MMS)	64	0.316408760567558	0	0	1	J01AA.profile.ud50
mms_mouse_lymph_low_4hrs_up	15515172	Up-regulated at 4 hours following treatment of mouse lymphocytes (TK 3.7.2C) with a low dose of methyl methanesulfonate (MMS)	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
mouse_tissue_adrenal	11904358	Genes expressed specifically in mouse adrenal gland tissue	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
mouse_tissue_bradipose	11904358	Genes expressed specifically in mouse brown adipose tissue	4	0.0197755475354724	0	0	1	J01AA.profile.ud50
mouse_tissue_cerebellum	11904358	Genes expressed specifically in mouse cerebellum tissue	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
mouse_tissue_eye	11904358	Genes expressed specifically in mouse eye tissue	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
mouse_tissue_kidney	11904358	Genes expressed specifically in mouse kidney tissue	20	0.098877737677362	1	10.1135	0.0943686610871122	J01AA.profile.ud50
mouse_tissue_mammary	11904358	Genes expressed specifically in mouse mammary gland tissue	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
mouse_tissue_placenta	11904358	Genes expressed specifically in mouse placenta tissue	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
mouse_tissue_salivary	11904358	Genes expressed specifically in mouse salivary gland tissue	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
mouse_tissue_smintestine	11904358	Genes expressed specifically in mouse small intestine tissue	3	0.0148316606516043	0	0	1	J01AA.profile.ud50
mouse_tissue_stomach	11904358	Genes expressed specifically in mouse stomach tissue	2	0.00988777376773619	0	0	1	J01AA.profile.ud50
mouse_tissue_prostate	11904358	Genes expressed specifically in mouse testis tissue	47	0.232362683541801	0	0	1	J01AA.profile.ud50
mouse_tissue_thymus	11904358	Genes expressed specifically in mouse thymus tissue	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
mtx_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to methotrexate	10	0.049438868838681	0	0	1	J01AA.profile.ud50
myc_targets	14519204	Myc-responsive genes reported in multiple systems	77	0.380679290057844	0	0	1	J01AA.profile.ud50
myod_brg1_up	15870273	Genes up-regulated following transduction of MyoD in NIH 3T3 cells that fail to acheive full induction with expression of a dominant-negative BRG1 allele; induction thought to require functional BRG1 	40	0.197755475354724	0	0	1	J01AA.profile.ud50
myod_nih3t3_dn	15870273	Down-regulated at 24 hours in NIH 3T3 murine fibroblasts following transduction with MyoD and incubation in differentiation medium	91	0.449893706431997	0	0	1	J01AA.profile.ud50
myod_nih3t3_up	15870273	Up-regulated at 24 hours in NIH 3T3 murine fibroblasts following transduction with MyoD and incubation in differentiation medium	134	0.662480842438325	0	0	1	J01AA.profile.ud50
nab_lung_dn	15318170	Down-regulated in human non-small cell lung carcinoma cell line H460 following 24-hour treatment with sodium butyrate	96	0.474613140851337	0	0	1	J01AA.profile.ud50
nab_lung_up	15318170	Up-regulated in human non-small cell lung carcinoma cell line H460 following 24-hour treatment with sodium butyrate	38	0.187867701586988	0	0	1	J01AA.profile.ud50
nf90_dn	12036489	Downregulated by ectopic expression of NF90 in GHOST(3)CXCR4 cells	66	0.326296534335294	1	3.06469696969697	0.278992535853036	J01AA.profile.ud50
nf90_up	12036489	Upregulated by ectopic expression of NF90 in GHOST(3)CXCR4 cells	56	0.276857665496613	0	0	1	J01AA.profile.ud50
ni2_lung_dn	12915101	Downregulated by nickel(II) in human peripheral lung epithelial cells	40	0.197755475354724	0	0	1	J01AA.profile.ud50
ni2_lung_up	12915101	Upregulated by nickel(II) in human peripheral lung epithelial cells	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
ni2_mouse_dn	12540486	Downregulated by nickel(II) in sensitive A/J mouse lung tissue	89	0.440005932664261	0	0	1	J01AA.profile.ud50
ni2_mouse_up	12540486	Upregulated by nickel(II) in sensitive A/J mouse lung tissue	65	0.321352647451426	0	0	1	J01AA.profile.ud50
nova2_ko_splicing	16041372	Genes that are alternatively spliced in the neocortex of mice deficient in the neuron-specific splicing factor Nova2, compared to wild-type controls	85	0.420230385128788	0	0	1	J01AA.profile.ud50
o6bg_resist_medulloblastoma_dn	12479369	Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED)	109	0.538883670341623	0	0	1	J01AA.profile.ud50
o6bg_resist_medulloblastoma_up	12479369	Up-regulated in a medulloblastoma cell line resistant to both BCNU and O6-BG, compared to sensitive parent line (D-341 MED)	46	0.227418796657932	0	0	1	J01AA.profile.ud50
oldage_dn	10741968	Downregulated in fibroblasts from old individuals, compared to young	76	0.375735403173975	0	0	1	J01AA.profile.ud50
oldage_up	10741968	Upregulated in fibroblasts from old individuals, compared to young	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
old_fibro_dn	14527998	Downregulated in fibroblasts from old individuals, compared to young	211	1.04316013249617	0	0	1	J01AA.profile.ud50
old_fibro_up	14527998	Upregulated in fibroblasts from old individuals, compared to young	84	0.41528649824492	1	2.40797619047619	0.340528458282614	J01AA.profile.ud50
oldonly_fibro_dn	14527998	Downregulated in fibroblasts from old (but not Werner) individuals, compared to young	61	0.301577099915954	0	0	1	J01AA.profile.ud50
oldonly_fibro_up	14527998	Upregulated in fibroblasts from old (but not Werner) individuals, compared to young	54	0.266969891728877	1	3.74574074074074	0.234810688221538	J01AA.profile.ud50
oldwerner_fibro_dn	14527998	Commonly downregulated in fibroblasts from Werner Syndrome and old individuals, compared to young	150	0.741583032580215	0	0	1	J01AA.profile.ud50
oldwerner_fibro_up	14527998	Commonly upregulated in fibroblasts from Werner Syndrome and old individuals, compared to young	30	0.148316606516043	0	0	1	J01AA.profile.ud50
oxstress_breastca_dn	12414654	Downregulated by H2O2, Menadione and t-BH in breast cancer cells	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
oxstress_breastca_up	12414654	Upregulated by H2O2, Menadione and t-BH in breast cancer cells	45	0.222474909774064	0	0	1	J01AA.profile.ud50
oxstress_rpe_h2o2hne_dn	12419474	Downregulated by H2O2 and HNE in retinal pigment epithelium cells (Tables 4)	73	0.360903742522371	0	0	1	J01AA.profile.ud50
oxstress_rpe_h2o2tbh_dn	12419474	Downregulated by H2O2 and t-BH in retinal pigment epithelium cells (Tables 5)	67	0.331240421219163	0	0	1	J01AA.profile.ud50
oxstress_rpe_hnetbh_dn	12419474	Downregulated by HNE and t-BH in retinal pigment epithelium cells (Tables 3)	137	0.677312503089929	0	0	1	J01AA.profile.ud50
oxstress_rpethree_dn	12419474	Downregulated by all three of H2O2, HNE and t-BH in retinal pigment epithelium cells (Table 2)	61	0.301577099915954	1	3.31590163934426	0.260902216156001	J01AA.profile.ud50
oxstress_rpetwo_dn	12419474	Downregulated by two of H2O2, HNE and t-BH in retinal pigment epithelium cells (Tables 3-5)	275	1.35956889306373	0	0	1	J01AA.profile.ud50
p21_any_dn	12138103	Down-regulated at any timepoint (4-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells	50	0.247194344193405	0	0	1	J01AA.profile.ud50
p21_any_up	12138103	Up-regulated at any timepoint (4-24 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
p21_early_dn	12138103	Down-regulated at early timepoints (4-8 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
p21_early_up	12138103	Up-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
p21_late_dn	12138103	Down-regulated at late timepoints (20-24 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells	8	0.0395510950709448	0	0	1	J01AA.profile.ud50
p21_middle_dn	12138103	Down-regulated at intermediate timepoints (12-16 hrs) follwing ectopic expression of p21 (CDKN1A) in OvCa cells	26	0.128541058980571	0	0	1	J01AA.profile.ud50
p21_p53_any_dn	12138103	Down-regulated at any timepoint (4-24 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent	77	0.380679290057844	1	2.62688311688312	0.31724788495548	J01AA.profile.ud50
p21_p53_early_dn	12138103	Down-regulated at early timepoints (4-8 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent	23	0.113709398328966	0	0	1	J01AA.profile.ud50
p21_p53_late_dn	12138103	Down-regulated at late timepoints (20-24 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
p21_p53_middle_dn	12138103	Down-regulated at intermediate timepoints (12-16 hrs) following ectopic expression of p21 (CDKN1A) in OvCa cells, p53-dependent	37	0.18292381470312	1	5.46675675675676	0.167546144853806	J01AA.profile.ud50
p53_brca1_up	12802282	Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1	49	0.242250457309537	0	0	1	J01AA.profile.ud50
p53genes_all	12446780	p53 transcriptional targets	33	0.163148267167647	1	6.12939393939394	0.150878416157636	J01AA.profile.ud50
p53genes_apoptosis	12446780	p53 transcriptional targets involved in apoptosis	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
p53genes_arrest	12446780	p53 transcriptional targets involved in cell cycle arrest	10	0.049438868838681	0	0	1	J01AA.profile.ud50
paclitaxel_probcell_up	12447701	Up-regulated in pro-B cells (FL5.12) following treatment with paclitaxel	5	0.0247194344193405	0	0	1	J01AA.profile.ud50
parp_ko_dn	11016956	Downregulated in MEF cells from PARP knockout mice	23	0.113709398328966	0	0	1	J01AA.profile.ud50
parp_ko_up	11016956	Upregulated in MEF cells from PARP knockout mice	61	0.301577099915954	0	0	1	J01AA.profile.ud50
pdgf_es_dn	14981515	Down-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
pdgf_es_up	14981515	Up-regulated by PDGF in mouse embryonic stem cells, via microarray-coupled gene-trap mutagenesis	28	0.138428832748307	0	0	1	J01AA.profile.ud50
pgj2_up	12032289	Upregulated by treatment with the prostaglandin 15d-PGJ2	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
pituitary_fetal_dn	15894316	Down-regulated in human fetal pituitary tissue, compared to adult pituitary tissue	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
pituitary_fetal_up	15894316	Up-regulated in human fetal pituitary tissue, compared to adult pituitary tissue	21	0.10382162456123	0	0	1	J01AA.profile.ud50
platelet_expressed	12433680	Fifty genes most strongly expressed in human platlets from three healthy donors	66	0.326296534335294	0	0	1	J01AA.profile.ud50
pod1_ko_dn	16207825	Down-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls	1135	5.61131161319029	3	0.53463436123348	0.918779197505357	J01AA.profile.ud50
pod1_ko_most_dn	16207825	Most strongly down-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls	43	0.212587136006328	0	0	1	J01AA.profile.ud50
pod1_ko_most_up	16207825	Most strongly up-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls	61	0.301577099915954	0	0	1	J01AA.profile.ud50
pod1_ko_up	16207825	Up-regulated in glomeruli isolated from Pod1 knockout mice, versus wild-type controls	508	2.51149453700499	1	0.398169291338583	0.919357006020447	J01AA.profile.ud50
preadip_vs_fibro_dn	12021175	Downregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
preadip_vs_fibro_up	12021175	Upregulated following 6hr differentiation of murine 3T3-L1 fibroblasts into preadipocytes; presumed direct transcriptional targets of differentiation cocktail of insulin, dexamethasone and isobutyl-methylxanthine	29	0.143372719632175	0	0	1	J01AA.profile.ud50
prmt5_kd_dn	15485929	Down-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells	45	0.222474909774064	0	0	1	J01AA.profile.ud50
prmt5_kd_up	15485929	Up-regulated by stable RNAi knock-down of PRMT5 in NIH 3T3 cells	306	1.51282938646364	0	0	1	J01AA.profile.ud50
pt650_colonca_dn	11755394	Downregulated by Pt-650, but not Et-743, in HCT116 cells (Fig. 6C)	24	0.118653285212834	0	0	1	J01AA.profile.ud50
pubertal_mammary	17486082	Differentially expressed (> 2-fold) in the developing mouse mammary gland at any time point between 3- and 7-weeks of age.	1260	6.2292974736738	6	0.963190476190476	0.59088268909895	J01AA.profile.ud50
pubertal_mammary_3-4wks_dn	17486082	Down-regulated > 1.5-fold in the developing mouse mammary gland between 3 and 4 weeks of age.	55	0.271913778612745	0	0	1	J01AA.profile.ud50
pubertal_mammary_3-4wks_up	17486082	Up-regulated > 1.5-fold in the developing mouse mammary gland between 3 and 4 weeks of age.	301	1.4881099520443	3	2.01598006644518	0.187856283259564	J01AA.profile.ud50
pubertal_mammary_4-5wks_dn	17486082	Down-regulated > 1.5-fold in the developing mouse mammary gland between 4 and 5 weeks of age.	283	1.39911998813467	2	1.42946996466431	0.408204807743202	J01AA.profile.ud50
pubertal_mammary_4-5wks_up	17486082	Up-regulated > 1.5-fold in the developing mouse mammary gland between 4 and 5 weeks of age.	368	1.81935037326346	1	0.549646739130435	0.838598879780963	J01AA.profile.ud50
pubertal_mammary_5-6wks_dn	17486082	Down-regulated > 1.5-fold in the developing mouse mammary gland between 5 and 6 weeks of age.	256	1.26563504227023	2	1.580234375	0.361189377942571	J01AA.profile.ud50
pubertal_mammary_5-6wks_up	17486082	Up-regulated > 1.5-fold in the developing mouse mammary gland between 5 and 6 weeks of age.	143	0.706975824393138	0	0	1	J01AA.profile.ud50
pubertal_mammary_6-7wks_dn	17486082	Down-regulated > 1.5-fold in the developing mouse mammary gland between 6 and 7 weeks of age.	106	0.524052009690018	0	0	1	J01AA.profile.ud50
pubertal_mammary_6-7wks_up	17486082	Up-regulated > 1.5-fold in the developing mouse mammary gland between 6 and 7 weeks of age.	363	1.79463093884412	2	1.11443526170799	0.536151027858328	J01AA.profile.ud50
ra_saha_up	11696577	Upregulated by the combination of retinoic acid and the HDACi SAHA in NB4 (APL) cells	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
ras-grf1_ko_dn	17321057	Down-regulated in LCM-dissected hippocampus samples of Ras-GRF1 knockout mice compared to wild-type controls.	41	0.202699362238592	0	0	1	J01AA.profile.ud50
ras-grf1_ko_up	17321057	Up-regulated in LCM-dissected hippocampus samples of Ras-GRF1 knockout mice compared to wild-type controls.	10	0.049438868838681	0	0	1	J01AA.profile.ud50
rb_creko_dn	17452985	Down-regulated at 144 hours after disruption of Rb in adult mouse fibroblasts by Cre recombination, versus GFP controls.	250	1.23597172096702	0	0	1	J01AA.profile.ud50
rb_creko_up	17452985	Up-regulated at 144 hours after disruption of Rb in adult mouse fibroblasts by Cre recombination, versus GFP controls.	344	1.70069708805063	2	1.17598837209302	0.507510051745443	J01AA.profile.ud50
rb_ko_dn	17452985	Down-regulated in MEFs derived from Rb knock-out mice, versus wild-type controls.	149	0.736639145696346	0	0	1	J01AA.profile.ud50
rb_ko_up	17452985	Up-regulated in MEFs derived from Rb knock-out mice, versus wild-type controls.	155	0.766302466999555	2	2.60993548387097	0.178941904214836	J01AA.profile.ud50
rcc_nl_up	12692265	Upregulated in VHL-rescued renal carcinoma vs. normal renal cells (Fig. 2d+e)	899	4.44455430859742	5	1.12497219132369	0.457551217532211	J01AA.profile.ud50
refractory_gastric_dn	15033468	Downregulated in samples of gastric cancer refractory to 5-FU/cisplatin treatment, compared to chemosensitive controls	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
refractory_gastric_up	15033468	Upregulated in samples of gastric cancer refractory to 5-FU/cisplatin treatment, compared to chemosensitive controls	204	1.00855292430909	1	0.991519607843137	0.636164798758892	J01AA.profile.ud50
reovirus_hek293_dn	12885910	Down-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney	488	2.41261679932763	1	0.414487704918033	0.910953839035257	J01AA.profile.ud50
reovirus_hek293_up	12885910	Up-regulated at any timepoint up to 24 hours following infection of HEK293 cells with reovirus strain T3Abney	491	2.42744845997924	0	0	1	J01AA.profile.ud50
resistance_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to at least six of seven anticancer drugs tested	45	0.222474909774064	0	0	1	J01AA.profile.ud50
rett_dn	12418965	Downregulated by expression of mutant MeCP2 (Rett syndrome) vs. wt MeCP2 in fibroblasts	31	0.153260493399911	0	0	1	J01AA.profile.ud50
rett_up	12418965	Upregulated by expression of mutant MeCP2 (Rett syndrome) vs. wt MeCP2 in fibroblasts	71	0.351015968754635	1	2.84887323943662	0.296640072911705	J01AA.profile.ud50
ribavirin_rsv_dn	12719586	Up-regulation by infection of human pulmonary epithelian cells (A549) with respiratory syncytial virus (RSV) is inhibited by the anti-viral drug ribavirin	101	0.499332575270678	0	0	1	J01AA.profile.ud50
ribavirin_rsv_up	12719586	Up-regulation by infection of human pulmonary epithelian cells (A549) with respiratory syncytial virus (RSV) is enhanced by the anti-viral drug ribavirin	37	0.18292381470312	0	0	1	J01AA.profile.ud50
ros_mouse_aorta_dn	15054141	Down-regulated in mouse aorta by chronic treatment with PPARgamma agonist rosiglitazone	127	0.627873634251248	1	1.59267716535433	0.467104981113997	J01AA.profile.ud50
ros_mouse_aorta_up	15054141	Up-regulated in mouse aorta by chronic treatment with PPARgamma agonist rosiglitazone	30	0.148316606516043	0	0	1	J01AA.profile.ud50
sarcomas_gistromal_dn	11965276	Top 20 negative significant genes associated with GI stromal tumors, versus other soft-tissue tumors.	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
sarcomas_gistromal_up	11965276	Top 20 positive significant genes associated with GI stromal tumors, versus other soft-tissue tumors.	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
sarcomas_histiocytoma_dn	11965276	Top 20 negative significant genes associated with malignant fibrous histiocytomas, versus other soft-tissue tumors.	10	0.049438868838681	0	0	1	J01AA.profile.ud50
sarcomas_histiocytoma_up	11965276	Top 20 positive significant genes associated with malignant fibrous histiocytomas, versus other soft-tissue tumors.	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
sarcomas_leiomyosarcoma_calp_dn	11965276	Top 20 negative significant genes associated with calponin positive leiomyosarcoma tumors, versus other soft-tissue tumors.	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
sarcomas_leiomyosarcoma_calp_up	11965276	Top 20 positive significant genes associated with calponin positive leiomyosarcoma tumors, versus other soft-tissue tumors.	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
sarcomas_leiomyosarcoma_dn	11965276	Top 20 negative significant genes associated with calponin negative leiomyosarcoma tumors, versus other soft-tissue tumors.	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
sarcomas_leiomyosarcoma_up	11965276	Top 20 positive significant genes associated with calponin negative leiomyosarcoma tumors, versus other soft-tissue tumors.	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
sarcomas_liposarcoma_dn	11965276	Top 20 negative significant genes associated with liposarcomas, versus other soft-tissue tumors.	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
sarcomas_liposarcoma_up	11965276	Top 20 positive significant genes associated with liposarcomas, versus other soft-tissue tumors.	14	0.0692144163741534	1	14.4478571428571	0.0670335858789568	J01AA.profile.ud50
sarcomas_schwannoma_dn	11965276	Top 20 negative significant genes associated with schwannomas, versus other soft-tissue tumors.	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
sarcomas_schwannoma_up	11965276	Top 20 positive significant genes associated with schwannomas, versus other soft-tissue tumors.	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
sarcomas_synovial_dn	11965276	Top 20 negative significant genes associated with synovial sarcomas, versus other soft-tissue tumors.	29	0.143372719632175	0	0	1	J01AA.profile.ud50
sarcomas_synovial_up	11965276	Top 20 positive significant genes associated with synovial sarcomas, versus other soft-tissue tumors.	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
scar_fibro_dn	15095275	Downregulated in hypertrophic scar fibroblasts, compared to normal skin fibroblasts	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
scar_fibro_up	15095275	Upregulated in hypertrophic scar fibroblasts, compared to normal skin fibroblasts	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
scchn_hpvneg_dn	17079134	Down-regulated in HPV-negative squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium.	47	0.232362683541801	0	0	1	J01AA.profile.ud50
scchn_hpvneg_up	17079134	Up-regulated in HPV-negative squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium.	30	0.148316606516043	0	0	1	J01AA.profile.ud50
scchn_hpvpos_dn	17079134	Down-regulated in HPV-positive squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium.	25	0.123597172096702	0	0	1	J01AA.profile.ud50
scchn_hpvpos_up	17079134	Up-regulated in HPV-positive squamous cell carcinomas of the head and neck (SCCHN) vs. normal oral epithelium.	31	0.153260493399911	0	0	1	J01AA.profile.ud50
scw_joint_24hrs_dn	15642130	Down-regulated in rat ankle joints 24 hrs following intra-articular injection of Streptococcal cell wall (SCW), a rat model of arthritis.	24	0.118653285212834	0	0	1	J01AA.profile.ud50
scw_joint_24hrs_up	15642130	Up-regulated in rat ankle joints 24 hrs following intra-articular injection of Streptococcal cell wall (SCW), a rat model of arthritis.	143	0.706975824393138	0	0	1	J01AA.profile.ud50
scw_joint_4hrs_up	15642130	Up-regulated in rat ankle joints 4 hrs following intra-articular injection of Streptococcal cell wall (SCW), a rat model of arthritis.	230	1.13709398328966	1	0.879434782608696	0.680153509053981	J01AA.profile.ud50
scw_joint_react_dn	15642130	Down-regulated in rat ankle joints 16 days after intra-articular injection of Streptococcal cell wall (SCW), and 3 days after systemic injection of SCW to reactivate joint inflammation.	231	1.14203787017353	0	0	1	J01AA.profile.ud50
scw_joint_react_up	15642130	Up-regulated in rat ankle joints 16 days after intra-articular injection of Streptococcal cell wall (SCW), and 3 days after systemic injection of SCW to reactivate joint inflammation.	166	0.820685222722104	0	0	1	J01AA.profile.ud50
senescence_hela_dn	17182682	Down-regulated in HeLa/HPV16E6 cells 6 days following induction of senescence by repression of HPV E7 via HPV E2 and subsequent reactivation of Rb.	341	1.68586542739902	1	0.59316715542522	0.815489070326862	J01AA.profile.ud50
senescence_hela_up	17182682	Up-regulated in HeLa/HPV16E6 cells 6 days following induction of senescence by repression of HPV E7 via HPV E2 and subsequent reactivation of Rb.	262	1.29529836357344	1	0.772022900763359	0.727062066753205	J01AA.profile.ud50
senescence_hff_dn	17182682	Down-regulated in primary human foreskin fibroblasts at replicative senescence (passage 26) compared to active replication (passage 8).	299	1.47822217827656	1	0.676488294314381	0.772791765253071	J01AA.profile.ud50
senescence_hff_up	17182682	Up-regulated in primary human foreskin fibroblasts at replicative senescence (passage 26) compared to active replication (passage 8).	284	1.40406387501854	1	0.712218309859155	0.755256883718259	J01AA.profile.ud50
senescence_rep-ind_dn	17182682	Down-regulated in models of both replicative (high-passge human foreskin fibroblast) and induced (repression of E7 in HeLa) cellular senescence.	171	0.845404657141445	0	0	1	J01AA.profile.ud50
senescence_rep-ind_up	17182682	Up-regulated in models of both replicative (high-passge human foreskin fibroblast) and induced (repression of E7 in HeLa) cellular senescence.	31	0.153260493399911	0	0	1	J01AA.profile.ud50
serum_fibroblast_cellcycle	14737219	Cell-cycle dependent genes regulated following exposure to serum in a variety of human fibroblast cell lines 	197	0.973945716122015	0	0	1	J01AA.profile.ud50
serum_fibroblast_core_dn	14737219	Core group of genes consistently down-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in quiescent cells, not cell-cycle dependent)  	319	1.57709991595392	3	1.90222570532915	0.210470593489558	J01AA.profile.ud50
serum_fibroblast_core_up	14737219	Core group of genes consistently up-regulated following exposure to serum in a variety of human fibroblast cell lines (higher expression in activated cells, not cell-cycle dependent)  	292	1.44361497008948	1	0.692705479452055	0.764770891515624	J01AA.profile.ud50
shh_up	12444557	Upregulated by sonic hedgehog (shh) expression in murine neuronal precursor cells	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
shortattacklatency_up	14635221	Up-regulated in hippocampi from a mouse line selected for long attack latency (LAL) against an intruder, versus a line selected for short attack latency (SAL).	156	0.771246353883423	1	1.29660256410256	0.538447345941993	J01AA.profile.ud50
space_up	12039873	Upregulated in space-flown fibroblasts	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
stemcell_common_dn	12228720	Depleted in mouse embryonic, neural and hematopoietic stem cells, compared to differentiated brain and bone marrow cells	104	0.514164235922282	0	0	1	J01AA.profile.ud50
stemcell_common_up	12228720	Enriched in mouse embryonic, neural and hematopoietic stem cells, compared to differentiated brain and bone marrow cells	265	1.31013002422505	1	0.763283018867924	0.731090209078262	J01AA.profile.ud50
stemcell_embryonic_up	12228720	Enriched in mouse embryonic stem cells, compared to differentiated brain and bone marrow cells	1989	9.83339101201365	9	0.91524886877828	0.64863993317517	J01AA.profile.ud50
stemcell_hematopoietic_up	12228720	Enriched in mouse hematopoietic stem cells, compared to differentiated brain and bone marrow cells	2092	10.3426113610521	7	0.676811663479923	0.890613510683873	J01AA.profile.ud50
stemcell_neural_up	12228720	Enriched in mouse neural stem cells, compared to differentiated brain and bone marrow cells	2805	13.86760270925	11	0.79321568627451	0.816035720127954	J01AA.profile.ud50
stress_arsenic_specific_dn	15824734	Genes down-regulated 4 hours following arsenic treatment that discriminate arsenic from other stress agents 	48	0.237306570425669	1	4.21395833333333	0.211714637447666	J01AA.profile.ud50
stress_arsenic_specific_up	15824734	Genes up-regulated 4 hours following arsenic treatment that discriminate arsenic from other stress agents 	266	1.31507391110891	1	0.760413533834586	0.732419668666543	J01AA.profile.ud50
stress_genotoxic_specific_dn	15824734	Genes down-regulated 4 hours following genotoxic stress that discriminate genotoxic from non-genotoxic stress 	74	0.365847629406239	1	2.73337837837838	0.30702057905224	J01AA.profile.ud50
stress_genotoxic_specific_up	15824734	Genes up-regulated 4 hours following genotoxic stress that discriminate genotoxic from non-genotoxic stress 	67	0.331240421219163	0	0	1	J01AA.profile.ud50
stress_ionizing_specific_dn	15824734	Genes down-regulated 4 hours following ionizing radiation treatment that discriminate IR from other stress agents 	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
stress_ionizing_specific_up	15824734	Genes up-regulated 4 hours following ionizing radiation treatment that discriminate IR from other stress agents 	29	0.143372719632175	0	0	1	J01AA.profile.ud50
stress_p53_specific_up	15824734	Genes discriminating p53 status 4 hours after DNA-damaging treatments (more strongly up-regulated in p53+/+ TK6 cells than p53-/- NH32 cells)	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
stress_tpa_specific_dn	15824734	Genes down-regulated 4 hours following TPA treatment that discriminate TPA from other stress agents 	5	0.0247194344193405	1	40.454	0.0244762196457262	J01AA.profile.ud50
stress_tpa_specific_up	15824734	Genes up-regulated 4 hours following TPA treatment that discriminate TPA from other stress agents 	78	0.385623176941712	1	2.59320512820513	0.320623334181982	J01AA.profile.ud50
tafi_kd_dn	17179179	Down-regulated by stable siRNA knock-down of histone chaperone TAF-I in HeLa cells.	62	0.306520986799822	0	0	1	J01AA.profile.ud50
tafi_kd_up	17179179	Up-regulated by stable siRNA knock-down of histone chaperone TAF-I in HeLa cells.	20	0.098877737677362	0	0	1	J01AA.profile.ud50
tcell_anergic_up	15834410	Genes up-regulated in anergic mouse T helper cells (A.E7), versus non-anergic stimulated controls	132	0.652593068670589	0	0	1	J01AA.profile.ud50
tff2_ko_dn	16121031	Down-regulated in pyloric atrium tissue from Trefoil Factor 2 (Tff2) knockout mice, compared to wild-type controls	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
tff2_ko_up	16121031	Up-regulated in pyloric atrium tissue from Trefoil Factor 2 (Tff2) knockout mice, compared to wild-type controls	36	0.177979927819252	1	5.61861111111111	0.163410139213889	J01AA.profile.ud50
tgfbeta_all_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, at any timepoint	200	0.988777376773619	0	0	1	J01AA.profile.ud50
tgfbeta_c1_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 1	42	0.20764324912246	0	0	1	J01AA.profile.ud50
tgfbeta_c2_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 2	46	0.227418796657932	0	0	1	J01AA.profile.ud50
tgfbeta_c3_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 3	38	0.187867701586988	0	0	1	J01AA.profile.ud50
tgfbeta_c4_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 4	26	0.128541058980571	0	0	1	J01AA.profile.ud50
tgfbeta_c5_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 5	41	0.202699362238592	0	0	1	J01AA.profile.ud50
tgfbeta_c6_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts, cluster 6	7	0.0346072081870767	0	0	1	J01AA.profile.ud50
tgfbeta_early_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts at 30 min (clusters 1-3)	126	0.62292974736738	0	0	1	J01AA.profile.ud50
tgfbeta_late_up	11279127	Upregulated by TGF-beta treatment of skin fibroblasts only at 1-4 hrs (clusters 4-6)	74	0.365847629406239	0	0	1	J01AA.profile.ud50
tgfb_hmvec_2hr_dn	16405919	Down-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta.	353	1.74519207000544	0	0	1	J01AA.profile.ud50
tgfb_hmvec_2hr_up	16405919	Up-regulated 2 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta.	1997	9.87294210708459	13	1.31673009514271	0.196069319314222	J01AA.profile.ud50
tgfb_hmvec_4hr_dn	16405919	Down-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta.	1321	6.53087457358976	5	0.76559424678274	0.78045294799463	J01AA.profile.ud50
tgfb_hmvec_4hr_up	16405919	Up-regulated 4 hr following treatment of human microvessel endothelial cells (HMVEC) with TGFbeta.	1997	9.87294210708459	13	1.31673009514271	0.196069319314222	J01AA.profile.ud50
tgfb_mammary_dn	17210685	Down-regulated in normal mouse mammary gland cells following treatment with TGF-beta (top 124 genes).	106	0.524052009690018	1	1.90820754716981	0.408652662167353	J01AA.profile.ud50
tgfb_mammary_up	17210685	Up-regulated in normal mouse mammary gland cells following treatment with TGF-beta (top 124 genes).	118	0.583378652296435	0	0	1	J01AA.profile.ud50
tgfb-wnt3a_mammary_dn	17210685	Down-regulated in common by both TGF-beta and Wnt3A in normal mouse mammary gland cells (top 124 genes).	106	0.524052009690018	0	0	1	J01AA.profile.ud50
tgfb-wnt3a_mammary_up	17210685	Up-regulated in common by both TGF-beta and Wnt3A in normal mouse mammary gland cells (top 124 genes).	136	0.672368616206061	0	0	1	J01AA.profile.ud50
tgz_adip_up	12732648	Upregulated in mature, differentiated adipocytes following treatment with troglitazone	43	0.212587136006328	0	0	1	J01AA.profile.ud50
tis7_overexp_dn	12198164	Downregulated by overexpression of TIS7 in murine mammary epithelial cells	27	0.133484945864439	0	0	1	J01AA.profile.ud50
tnfalpha_30min_up	12673210	Upregulated 30min after TNF-alpha treatment of HeLa cells	68	0.336184308103031	1	2.97455882352941	0.286104071666299	J01AA.profile.ud50
tnfalpha_4hrs_up	12673210	Upregulated 4hrs after TNF-alpha treatment of HeLa cells	62	0.306520986799822	0	0	1	J01AA.profile.ud50
tnfalpha_adip_dn	12732648	Downregulated in mature, differentiated adipocytes following treatment with TNFalpha	101	0.499332575270678	0	0	1	J01AA.profile.ud50
tnfalpha_adip_up	12732648	Upregulated in mature, differentiated adipocytes following treatment with TNFalpha	22	0.108765511445098	0	0	1	J01AA.profile.ud50
tnfalpha_all_up	12673210	Upregulated at any timepoint after TNF-alpha treatment of HeLa cells	122	0.603154199831908	1	1.65795081967213	0.453734465916889	J01AA.profile.ud50
tnfalpha_tgz_adip_dn	12732648	Downregulated in mature, differentiated adipocytes following simultaneous treatment with troglitazone and TNFalpha	39	0.192811588470856	0	0	1	J01AA.profile.ud50
tnfalpha_tgz_adip_up	12732648	Upregulated in mature, differentiated adipocytes following simultaneous treatment with troglitazone and TNFalpha	28	0.138428832748307	0	0	1	J01AA.profile.ud50
tnfa_nfkb_dep_up	15722553	Up-regulated at any timepoint following TNFa treatment, only with functional NFkB	26	0.128541058980571	0	0	1	J01AA.profile.ud50
tnfa_nfkb_ind_dn	15722553	Down-regulated at any timepoint following TNFa treatment, independent of NFkB function	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
tnfa_nfkb_ind_up	15722553	Up-regulated at any timepoint following TNFa treatment, independent of NFkB function	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
tpa_resist_early_dn	12384596	Downregulated by TPA at two consecutive timepoints between 15min-3hrs in resistant HL-525 cells	140	0.692144163741534	0	0	1	J01AA.profile.ud50
tpa_resist_early_up	12384596	Upregulated by TPA at two consecutive timepoints between 15min-3hrs in resistant HL-525 cells	57	0.281801552380482	0	0	1	J01AA.profile.ud50
tpa_resist_late_dn	12384596	Downregulated by TPA at two consecutive timepoints between 12-48 hrs in resistant HL-525 cells	112	0.553715330993227	0	0	1	J01AA.profile.ud50
tpa_resist_late_up	12384596	Upregulated by TPA at two consecutive timepoints between 12-48 hrs in resistant HL-525 cells	79	0.39056706382558	0	0	1	J01AA.profile.ud50
tpa_resist_middle_dn	12384596	Downregulated by TPA at two consecutive timepoints between 2-24hrs in resistant HL-525 cells	209	1.03327235872843	0	0	1	J01AA.profile.ud50
tpa_resist_middle_up	12384596	Upregulated by TPA at two consecutive timepoints between 2-24hrs in resistant HL-525 cells	100	0.49438868838681	0	0	1	J01AA.profile.ud50
tpa_sens_early_dn	12384596	Downregulated by TPA at two consecutive timepoints between 15min-3hrs in sensitive HL-60 cells	564	2.78835220250161	2	0.717269503546099	0.767690845333403	J01AA.profile.ud50
tpa_sens_early_up	12384596	Upregulated by TPA at two consecutive timepoints between 15min-3hrs in sensitive HL-60 cells	97	0.479557027735205	0	0	1	J01AA.profile.ud50
tpa_sens_late_dn	12384596	Downregulated by TPA at two consecutive timepoints between 12-48 hrs in sensitive HL-60 cells	451	2.22969298462451	2	0.896984478935698	0.65334027400134	J01AA.profile.ud50
tpa_sens_late_up	12384596	Upregulated by TPA at two consecutive timepoints between 12-48 hrs in sensitive HL-60 cells	95	0.469669253967469	0	0	1	J01AA.profile.ud50
tpa_sens_middle_dn	12384596	Downregulated by TPA at two consecutive timepoints between 2-24hrs in sensitive HL-60 cells	561	2.77352054185	2	0.721105169340463	0.765135299995611	J01AA.profile.ud50
tpa_sens_middle_up	12384596	Upregulated by TPA at two consecutive timepoints between 2-24hrs in sensitive HL-60 cells	114	0.563603104760963	0	0	1	J01AA.profile.ud50
tpa_skin_dn	12640676	Downregulated in murine dorsal skin cells 6 hours after treatment with the phorbol ester carcinogen TPA	25	0.123597172096702	0	0	1	J01AA.profile.ud50
tpa_skin_up	12640676	Upregulated in murine dorsal skin cells 6 hours after treatment with the phorbol ester carcinogen TPA	31	0.153260493399911	0	0	1	J01AA.profile.ud50
tsa_cd4_dn	14606959	Down-regulated in mouse CD4+ T-cells following 4 hour treatment with 100 nM trichostatin A	33	0.163148267167647	0	0	1	J01AA.profile.ud50
tsa_cd4_up	14606959	Up-regulated in mouse CD4+ T-cells following 4 hour treatment with 100 nM trichostatin A	43	0.212587136006328	0	0	1	J01AA.profile.ud50
tsadac_hypermeth_hyperac_ovca_up	12727835	Genes with basally hypermethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells, with hyperacetylated promoters upon activation	16	0.0791021901418896	0	0	1	J01AA.profile.ud50
tsadac_hypermeth_ovca_up	12727835	Genes with basally hypermethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
tsadac_hypometh_hyperac_ovca_up	12727835	Genes with basally hypomethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells, with hyperacetylated promoters upon activation	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
tsadac_hypometh_ovca_up	12727835	Genes with basally hypomethylated promoters upregulated by the combination of TSA and DAC in ovarian carcinoma (CP70) cells	70	0.346072081870767	0	0	1	J01AA.profile.ud50
tsadac_panc50_up	12839967	50 "most interesting" genes upregulated by the combination of TSA and DAC in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells	56	0.276857665496613	0	0	1	J01AA.profile.ud50
tsadac_rkoexp_up	11992124	Genes with some basal expression and partially-methylated promoters, upregulated by the combination of TSA and DAC in RKO cells	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
tsadac_rkosilent_up	11992124	Genes basally silent, with hypermethylated promoters, upregulated by the combination of TSA and DAC in RKO cells	30	0.148316606516043	1	6.74233333333333	0.13815897377783	J01AA.profile.ud50
tsa_hepatoma_cancer_dn	15452378	Cancer-related genes down-regulated in any of four human hepatoma cell lines following 24-hour treatment with 200ng/mL of trichostatin A	51	0.252138231077273	0	0	1	J01AA.profile.ud50
tsa_hepatoma_cancer_up	15452378	Cancer-related genes up-regulated in any of four human hepatoma cell lines following 24-hour treatment with 200ng/mL of trichostatin A	69	0.341128194986899	0	0	1	J01AA.profile.ud50
tsa_hepatoma_cancer_up_ac	15452378	Cancer-related genes up-regulated in any of four human hepatoma cell lines following 24-hour treatment with 200ng/mL of trichostatin A, which are associated by ChIP with acetylated histone H3 or H4	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
tsa_hepatoma_up	15336447	Up-regulated in more than one of several human hepatoma cell lines by 24-hour treatment with trichostatin A	67	0.331240421219163	1	3.0189552238806	0.282557115198203	J01AA.profile.ud50
tsa_hepg2_dn	16854234	Down-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 500 nM trichostatin A (TSA).	1237	6.11558807534484	4	0.654066289409862	0.859465626891888	J01AA.profile.ud50
tsa_hepg2_up	16854234	Up-regulated in human hepatoma cells (HepG2) following 24 hrs treatment with 500 nM trichostatin A (TSA).	936	4.62747812330054	7	1.51270299145299	0.18516622851528	J01AA.profile.ud50
tsa_panc50_up	12839967	50 "most interesting" genes upregulated by TSA treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells	77	0.380679290057844	0	0	1	J01AA.profile.ud50
tsa_rko_up	11992124	Upregulated by TSA alone, with non-hypermethylated promoters, in RKO cells	28	0.138428832748307	0	0	1	J01AA.profile.ud50
tzd_adip_dn	12021175	Downregulated by treatment of mature murine adipocytes with the PPARgamma agonist troglitazone	29	0.143372719632175	0	0	1	J01AA.profile.ud50
tzd_adip_up	12021175	Upregulated by treatment of mature murine adipocytes with the PPARgamma agonist troglitazone	11	0.0543827557225491	0	0	1	J01AA.profile.ud50
uv-4nqo_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with UV light or 4-NQO, but not by gamma radiation	48	0.237306570425669	0	0	1	J01AA.profile.ud50
uv-4nqo_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with UV light or 4-NQO, but not by gamma radiation	61	0.301577099915954	1	3.31590163934426	0.260902216156001	J01AA.profile.ud50
uvb_nhek1_c1	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes, cluster 1	112	0.553715330993227	1	1.80598214285714	0.42597860628403	J01AA.profile.ud50
uvb_nhek1_c2	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes, cluster 2	28	0.138428832748307	1	7.22392857142857	0.129573670122122	J01AA.profile.ud50
uvb_nhek1_c3	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes, cluster 3	26	0.128541058980571	0	0	1	J01AA.profile.ud50
uvb_nhek1_c4	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes, cluster 4	20	0.098877737677362	1	10.1135	0.0943686610871122	J01AA.profile.ud50
uvb_nhek1_c5	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes, cluster 5	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
uvb_nhek1_c6	12771951	Downregulated by UV-B light in normal human epidermal keratinocytes, cluster 6	268	1.32496168487665	1	0.754738805970149	0.735058902244318	J01AA.profile.ud50
uvb_nhek1_dn	12771951	Downregulated by UV-B light in normal human epidermal keratinocytes	542	2.67958669105651	3	1.11957564575646	0.501776528591888	J01AA.profile.ud50
uvb_nhek1_up	12771951	Upregulated by UV-B light in normal human epidermal keratinocytes	336	1.66114599297968	3	1.80598214285714	0.232336130453385	J01AA.profile.ud50
uvb_nhek2_dn	11982916	Downregulated by UV-B light in normal human epidermal keratinocytes	160	0.791021901418896	0	0	1	J01AA.profile.ud50
uvb_nhek2_up	11982916	Upregulated by UV-B light in normal human epidermal keratinocytes	125	0.617985860483512	0	0	1	J01AA.profile.ud50
uvb_nhek3_all	11867738	Regulated by UV-B light in normal human epidermal keratinocytes	751	3.71285904978494	2	0.53866844207723	0.885578476140921	J01AA.profile.ud50
uvb_nhek3_c0	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 0	167	0.825629109605972	1	1.21119760479042	0.562936493125841	J01AA.profile.ud50
uvb_nhek3_c1	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 1	104	0.514164235922282	0	0	1	J01AA.profile.ud50
uvb_nhek3_c2	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 2	89	0.440005932664261	1	2.27269662921348	0.356669828587795	J01AA.profile.ud50
uvb_nhek3_c3	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 3	37	0.18292381470312	0	0	1	J01AA.profile.ud50
uvb_nhek3_c4	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 4	20	0.098877737677362	0	0	1	J01AA.profile.ud50
uvb_nhek3_c5	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 5	85	0.420230385128788	0	0	1	J01AA.profile.ud50
uvb_nhek3_c6	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 6	47	0.232362683541801	0	0	1	J01AA.profile.ud50
uvb_nhek3_c7	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 7	86	0.425174272012656	0	0	1	J01AA.profile.ud50
uvb_nhek3_c8	11867738	Regulated by UV-B light in normal human epidermal keratinocytes, cluster 8	132	0.652593068670589	0	0	1	J01AA.profile.ud50
uvb_nhek4_1hr_dn	11532376	Downregulated at 1 hour by UV-B light in normal human epidermal keratinocytes	13	0.0642705294902853	0	0	1	J01AA.profile.ud50
uvb_nhek4_1hr_up	11532376	Upregulated at 1 hour by UV-B light in normal human epidermal keratinocytes	18	0.0889899639096258	0	0	1	J01AA.profile.ud50
uvb_nhek4_24hrs_dn	11532376	Downregulated at 24 hours by UV-B light in normal human epidermal keratinocytes	23	0.113709398328966	0	0	1	J01AA.profile.ud50
uvb_nhek4_24hrs_up	11532376	Upregulated at 24 hours by UV-B light in normal human epidermal keratinocytes	14	0.0692144163741534	0	0	1	J01AA.profile.ud50
uvb_nhek4_6hrs_dn	11532376	Downregulated at 6 hours by UV-B light in normal human epidermal keratinocytes	31	0.153260493399911	0	0	1	J01AA.profile.ud50
uvb_nhek4_6hrs_up	11532376	Upregulated at 6 hours by UV-B light in normal human epidermal keratinocytes	49	0.242250457309537	0	0	1	J01AA.profile.ud50
uvb_scc_dn	12771951	Downregulated by UV-B light in squamous cell carinoma cells	219	1.08271122756711	3	2.77082191780822	0.0956745145766639	J01AA.profile.ud50
uvb_scc_up	12771951	Upregulated by UV-B light in squamous cell carcinoma cells	198	0.978889603005883	0	0	1	J01AA.profile.ud50
uvc_high_all_dn	12907719	Down-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters d1-d9)	634	3.13442428437237	2	0.63807570977918	0.820770881601061	J01AA.profile.ud50
uvc_high_all_up	12907719	Up-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (clusters b1-b4)	34	0.168092154051515	0	0	1	J01AA.profile.ud50
uvc_high_b2_up	12907719	Up-regulated at 18-24 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster b2)	15	0.0741583032580215	0	0	1	J01AA.profile.ud50
uvc_high_b4_up	12907719	Progressively up-regulated from 12-24 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster b4)	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
uvc_high_d1_dn	12907719	Down-regulated at 6 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d1)	31	0.153260493399911	0	0	1	J01AA.profile.ud50
uvc_high_d2_dn	12907719	Down-regulated consistently at 6-24 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d2)	82	0.405398724477184	1	2.46670731707317	0.333959075686894	J01AA.profile.ud50
uvc_high_d3_dn	12907719	Progressively down-regulated through 12 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d3)	90	0.444949819548129	0	0	1	J01AA.profile.ud50
uvc_high_d4_dn	12907719	Progressively down-regulated through 12 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d4)	110	0.543827557225491	0	0	1	J01AA.profile.ud50
uvc_high_d5_dn	12907719	Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d5)	74	0.365847629406239	1	2.73337837837838	0.30702057905224	J01AA.profile.ud50
uvc_high_d6_dn	12907719	Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d6)	65	0.321352647451426	0	0	1	J01AA.profile.ud50
uvc_high_d7_dn	12907719	Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d7)	63	0.31146487368369	0	0	1	J01AA.profile.ud50
uvc_high_d8_dn	12907719	Progressively down-regulated through 18 hours following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d8)	70	0.346072081870767	0	0	1	J01AA.profile.ud50
uvc_high_d9_dn	12907719	Progressively down-regulated through 24 hrs following treatment of WS1 human skin fibroblasts with UVC at a high dose (50 J/m^2) (cluster d9)	53	0.262026004845009	0	0	1	J01AA.profile.ud50
uvc_low_a1_up	12907719	Up-regulated at 6 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster a1)	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
uvc_low_a2_up	12907719	Up-regulated at 6-12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster a2)	17	0.0840460770257577	0	0	1	J01AA.profile.ud50
uvc_low_a3_up	12907719	Up-regulated at 12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster a3)	6	0.0296633213032086	0	0	1	J01AA.profile.ud50
uvc_low_all_dn	12907719	Down-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (clusters c1-c5)	115	0.568546991644831	0	0	1	J01AA.profile.ud50
uvc_low_all_up	12907719	Up-regulated at any timepoint following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (clusters a1-a4)	33	0.163148267167647	0	0	1	J01AA.profile.ud50
uvc_low_c1_dn	12907719	Down-regulated at 6 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c1)	21	0.10382162456123	0	0	1	J01AA.profile.ud50
uvc_low_c2_dn	12907719	Down-regulated at 6-12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c2)	34	0.168092154051515	0	0	1	J01AA.profile.ud50
uvc_low_c3_dn	12907719	Down-regulated at 12 hours following treatment of WS1 human skin fibroblasts with UVC at a low dose (10 J/m^2) (cluster c3)	33	0.163148267167647	0	0	1	J01AA.profile.ud50
uv-cmv_unique_hcmv_6hrs_dn	11711622	Down-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV	164	0.810797448954368	0	0	1	J01AA.profile.ud50
uv-cmv_unique_hcmv_6hrs_up	11711622	Up-regulated in fibroblasts at 6 hours following infection with UV-inactivated CMV, but not untreated CMV	194	0.959114055470411	0	0	1	J01AA.profile.ud50
uvc_ttd_4hr_dn	15608684	Down-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	641	3.16903149255945	9	2.83998439937597	0.0052516987157134	J01AA.profile.ud50
uvc_ttd_4hr_up	15608684	Up-regulated at 4 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	105	0.51910812280615	0	0	1	J01AA.profile.ud50
uvc_ttd_8hr_dn	15608684	Down-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	382	1.88856478963761	3	1.58850785340314	0.293118251357279	J01AA.profile.ud50
uvc_ttd_8hr_up	15608684	Up-regulated at 8 hours following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	47	0.232362683541801	0	0	1	J01AA.profile.ud50
uvc_ttd_all_dn	15608684	Down-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	780	3.85623176941712	10	2.59320512820513	0.0062552359109377	J01AA.profile.ud50
uvc_ttd_all_up	15608684	Up-regulated at any timepoint following treatment of XPB/TTD fibroblasts with 3 J/m^2 UVC	140	0.692144163741534	0	0	1	J01AA.profile.ud50
uvc_ttd-xpcs_common_dn	15608684	Down-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC	344	1.70069708805063	6	3.52796511627907	0.00783845991206089	J01AA.profile.ud50
uvc_ttd-xpcs_common_up	15608684	Up-regulated at any timepoint following treatment of both XPB/CS and XPB/TTD fibroblasts with 3 J/m^2 UVC	44	0.217531022890196	0	0	1	J01AA.profile.ud50
uvc_xpcs_4hr_dn	15608684	Down-regulated at 4 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	519	2.56587729272754	2	0.779460500963391	0.726721027343549	J01AA.profile.ud50
uvc_xpcs_4hr_up	15608684	Up-regulated at 4 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	23	0.113709398328966	0	0	1	J01AA.profile.ud50
uvc_xpcs_8hr_dn	15608684	Down-regulated at 8 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	911	4.50388095120384	7	1.5542151481888	0.168970640984522	J01AA.profile.ud50
uvc_xpcs_8hr_up	15608684	Up-regulated at 8 hours following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	108	0.533939783457755	1	1.87287037037037	0.414485317140003	J01AA.profile.ud50
uvc_xpcs_all_dn	15608684	Down-regulated at any timepoint following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	1048	5.18119345429377	9	1.73705152671756	0.0800606856832166	J01AA.profile.ud50
uvc_xpcs_all_up	15608684	Up-regulated at any timepoint following treatment of XPB/CS fibroblasts with 3 J/m^2 UVC	112	0.553715330993227	1	1.80598214285714	0.42597860628403	J01AA.profile.ud50
uv_esr_old_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of fibroblasts from elderly donors with UV light	36	0.177979927819252	0	0	1	J01AA.profile.ud50
uv_esr_ws_unreg	15897889	Genes involved in the environmental stress response that were not regulated following treatment of Werner syndrome fibroblasts with UV light	23	0.113709398328966	0	0	1	J01AA.profile.ud50
uv_unique_fibro_dn	15897889	Down-regulated at any timepoint by treatment of human fibroblasts with UV light, but not bygamma radiation or 4-NQO	66	0.326296534335294	0	0	1	J01AA.profile.ud50
uv_unique_fibro_up	15897889	Up-regulated at any timepoint by treatment of human fibroblasts with UV light, but not bygamma radiation or 4-NQO	30	0.148316606516043	0	0	1	J01AA.profile.ud50
vcr_res_xenografts_dn	11809704	Down-regulation is correlated with resistance of human cancer xenografts to vincristine	9	0.0444949819548129	0	0	1	J01AA.profile.ud50
vcr_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to vincristine	12	0.0593266426064172	0	0	1	J01AA.profile.ud50
vegf_huvec_2hrs_up	12197474	Up-regulated 2 hours after VEGF treatment in human umbilical vein endothelial cells	54	0.266969891728877	0	0	1	J01AA.profile.ud50
vegf_huvec_30min_up	12197474	Up-regulated 30 minutes after VEGF treatment in human umbilical vein endothelial cells	41	0.202699362238592	0	0	1	J01AA.profile.ud50
vegf_huvec_up	12197474	20 genes with the largest fold-change up-regulation at any time point (30min to 24 hours) after VEGF treatment in human umbilical vein endothelial cells	24	0.118653285212834	2	16.8558333333333	0.00627539414166829	J01AA.profile.ud50
vegf_hmmec_12hrs_up	12200464	Up-regulated at 12hrs follwing VEGF treatment of human myometrial microvascular endothelial cells	38	0.187867701586988	0	0	1	J01AA.profile.ud50
vegf_hmmec_3hrs_up	12200464	Up-regulated at 3hrs follwing VEGF treatment of human myometrial microvascular endothelial cells	99	0.489444801502942	0	0	1	J01AA.profile.ud50
vegf_hmmec_6hrs_up	12200464	Up-regulated at 6hrs follwing VEGF treatment of human myometrial microvascular endothelial cells	88	0.435062045780393	0	0	1	J01AA.profile.ud50
vegf_hmmec_all_up	12200464	Up-regulated at any timepoint follwing VEGF treatment of human myometrial microvascular endothelial cells	147	0.72675137192861	0	0	1	J01AA.profile.ud50
ventricle_up	15103417	Upregulated in the ventricles of healthy hearts, compared to atria	373	1.8440698076828	1	0.542278820375335	0.84254936905051	J01AA.profile.ud50
vhl_normal_up	12692265	Upregulated in VHL-null renal carcinoma vs. normal renal cells (Fig. 2c+e)	754	3.72769071043655	4	1.07305039787798	0.51198549857427	J01AA.profile.ud50
vhl_rcc_up	12692265	Upregulated in VHL-null renal carcinoma cells vs. VHL-rescued (Fig. 1a+b)	153	0.756414693231819	6	7.9321568627451	0.000126720599959251	J01AA.profile.ud50
vlb_res_xenografts_up	11809704	Up-regulation is correlated with resistance of human cancer xenografts to vinblastine	28	0.138428832748307	0	0	1	J01AA.profile.ud50
werner_fibro_dn	14527998	Downregulated in fibroblasts from individuals with Werner syndrome, compared to normal, young individuals	238	1.17664507836061	0	0	1	J01AA.profile.ud50
werner_fibro_up	14527998	Upregulated in fibroblasts from individuals with Werner syndrome, compared to normal, young individuals	81	0.400454837593316	0	0	1	J01AA.profile.ud50
werneronly_fibro_dn	14527998	Downregulated in fibroblasts from Werner (but not old) individuals, compared to young	90	0.444949819548129	0	0	1	J01AA.profile.ud50
werneronly_fibro_up	14527998	Upregulated in fibroblasts from Werner (but not old) individuals, compared to young	51	0.252138231077273	0	0	1	J01AA.profile.ud50
wnt3a_mammary_dn	17210685	Down-regulated in normal mouse mammary gland cells following treatment with Wnt3A (top 124 genes).	100	0.49438868838681	0	0	1	J01AA.profile.ud50
wnt3a_mammary_up	17210685	Up-regulated in normal mouse mammary gland cells following treatment with Wnt3A (top 124 genes).	133	0.657536955554457	0	0	1	J01AA.profile.ud50
xpb_ttd-cs_dn	15608684	Down-regulated in XPB/TTD fibroblasts (expressing XPB-A355C), compared to XPB/CS fibroblasts (expressing XPB-T296C)	41	0.202699362238592	0	0	1	J01AA.profile.ud50
xpb_ttd-cs_up	15608684	Up-regulated in XPB/TTD fibroblasts (expressing XPB-A355C), compared to XPB/CS fibroblasts (expressing XPB-T296C)	57	0.281801552380482	0	0	1	J01AA.profile.ud50
zmpste24_ko_dn	16079796	Fifty genes most strongly down-regulated in liver tissue from mice deficient in the lamin-protease Zmpste24/Face1, versus wild-type controls	42	0.20764324912246	0	0	1	J01AA.profile.ud50
zmpste24_ko_up	16079796	Fifty genes most strongly up-regulated in liver tissue from mice deficient in the lamin-protease Zmpste24/Face1, versus wild-type controls	57	0.281801552380482	1	3.54859649122807	0.246103700580757	J01AA.profile.ud50