Results summary | View all lists in GO:MoleFunc | View all genes in J01EB.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
insulin receptor substrate binding | Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
transmembrane receptor protein tyrosine kinase signaling protein activity | 15 | 0.04 | 2 | 53.94 | 6.28e-04 | |
receptor signaling protein tyrosine kinase activity | 22 | 0.05 | 2 | 36.78 | 1.37e-03 | |
hormone binding | Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone. | 26 | 0.06 | 2 | 31.12 | 1.91e-03 |
SH2 domain binding | Interacting selectively with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class. | 29 | 0.07 | 2 | 27.90 | 2.37e-03 |
kinase binding | Interacting selectively with a kinase, any enzyme that catalyzes the transfer of a phosphate group. | 149 | 0.37 | 3 | 8.15 | 6.24e-03 |