L2L Microarray Analysis Tool
Results for L01AD.profile.u50
| Results summary | View all lists in GO:BiolProc | View all genes in L01AD.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| response to unfolded protein | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. | 83 | 0.21 | 8 | 38.99 | 4.66e-11 |
| response to protein stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. | 83 | 0.21 | 8 | 38.99 | 4.66e-11 |
| response to chemical stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. | 603 | 1.49 | 12 | 8.05 | 5.86e-08 |
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. | 319 | 0.79 | 9 | 11.41 | 1.46e-07 |
| response to biotic stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. | 282 | 0.70 | 8 | 11.48 | 6.86e-07 |
| glutathione biosynthetic process | The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. | 10 | 0.02 | 3 | 121.36 | 1.79e-06 |
| response to heat | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. | 15 | 0.04 | 3 | 80.91 | 6.72e-06 |
| glutathione metabolic process | The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. | 16 | 0.04 | 3 | 75.85 | 8.26e-06 |
| glutamate metabolic process | The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. | 17 | 0.04 | 3 | 71.39 | 1.00e-05 |
| response to stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). | 1358 | 3.36 | 14 | 4.17 | 1.14e-05 |
| sulfur amino acid metabolic process | The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine. | 28 | 0.07 | 3 | 43.34 | 4.72e-05 |
| serine family amino acid metabolic process | The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. | 34 | 0.08 | 3 | 35.69 | 8.53e-05 |
| programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 2.68 | 11 | 4.10 | 1.11e-04 |
| response to temperature stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. | 39 | 0.10 | 3 | 31.12 | 1.29e-04 |
| regulation of blood vessel size | Any process that modulates the size of blood vessels. | 43 | 0.11 | 3 | 28.22 | 1.73e-04 |
| cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 2.85 | 11 | 3.86 | 1.84e-04 |
| death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 2.85 | 11 | 3.86 | 1.84e-04 |
| coenzyme biosynthetic process | The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | 113 | 0.28 | 4 | 14.32 | 1.94e-04 |
| regulation of cell redox homeostasis | Any process that modulates the redox environment of a cell or compartment within a cell. | 9 | 0.02 | 2 | 89.90 | 2.17e-04 |
| sulfur compound biosynthetic process | The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. | 49 | 0.12 | 3 | 24.77 | 2.56e-04 |
| cofactor biosynthetic process | The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein. | 134 | 0.33 | 4 | 12.08 | 3.71e-04 |
| chaperone cofactor-dependent protein folding | The process of assisting in the correct noncovalent assembly of posttranslational proteins and is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
| cofactor metabolic process | The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. | 247 | 0.61 | 5 | 8.19 | 4.14e-04 |
| apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 2.66 | 10 | 3.75 | 4.43e-04 |
| glutamine family amino acid metabolic process | The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. | 60 | 0.15 | 3 | 20.23 | 4.65e-04 |
| cell redox homeostasis | The processes that maintain the redox environment of a cell or compartment within a cell. | 60 | 0.15 | 3 | 20.23 | 4.65e-04 |
| posttranslational protein folding | The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis. | 15 | 0.04 | 2 | 53.94 | 6.28e-04 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 5.83 | 15 | 2.57 | 1.05e-03 |
| cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 5.83 | 15 | 2.57 | 1.05e-03 |
| cell development | The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. | 1692 | 4.18 | 12 | 2.87 | 1.31e-03 |
| sulfur metabolic process | The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. | 89 | 0.22 | 3 | 13.64 | 1.46e-03 |
| response to oxidative stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. | 92 | 0.23 | 3 | 13.19 | 1.61e-03 |
| coenzyme metabolic process | The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | 201 | 0.50 | 4 | 8.05 | 1.67e-03 |
| negative regulation of programmed cell death | Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 347 | 0.86 | 5 | 5.83 | 1.87e-03 |
| response to stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. | 2860 | 7.07 | 16 | 2.26 | 2.61e-03 |
| prostanoid metabolic process | The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| prostaglandin metabolic process | The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. | 31 | 0.08 | 2 | 26.10 | 2.71e-03 |
| oxygen and reactive oxygen species metabolic process | The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). | 121 | 0.30 | 3 | 10.03 | 3.50e-03 |
| response to hormone stimulus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. | 36 | 0.09 | 2 | 22.47 | 3.64e-03 |
| regulation of programmed cell death | Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. | 793 | 1.96 | 7 | 3.57 | 4.02e-03 |
| regulation of biological quality | Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. | 832 | 2.06 | 7 | 3.40 | 5.19e-03 |
| anti-apoptosis | A process which directly inhibits any of the steps required for cell death by apoptosis. | 278 | 0.69 | 4 | 5.82 | 5.32e-03 |
| cellular component disassembly | A cellular process that results in the breakdown of a part of the cell. | 52 | 0.13 | 2 | 15.56 | 7.46e-03 |
| icosanoid metabolic process | The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids. | 58 | 0.14 | 2 | 13.95 | 9.21e-03 |
| water-soluble vitamin metabolic process | The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water. | 58 | 0.14 | 2 | 13.95 | 9.21e-03 |