Results summary | View all lists in GO:BiolProc | View all genes in L04AA.profile.u50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
keratinocyte differentiation | The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte. | 40 | 0.10 | 3 | 30.34 | 1.39e-04 |
negative regulation of survival gene product activity | Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. | 12 | 0.03 | 2 | 67.42 | 3.97e-04 |
defense response to virus | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. | 17 | 0.04 | 2 | 47.59 | 8.11e-04 |
cell aging | Progression of the cell from its inception to the end of its lifespan. | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
regulation of survival gene product activity | Any process that modulates the frequency, rate or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. | 21 | 0.05 | 2 | 38.53 | 1.24e-03 |
response to oxidative stress | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. | 92 | 0.23 | 3 | 13.19 | 1.61e-03 |
regulation of JNK activity | Any process that modulates the frequency, rate or extent of JUN kinase activity. | 30 | 0.07 | 2 | 26.97 | 2.54e-03 |
negative regulation of cellular process | Any process that stops, prevents or reduces the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 1642 | 4.06 | 11 | 2.71 | 3.12e-03 |
aging | The inherent decline over time, from the optimal fertility and viability of early maturity, that may precede death and may be preceded by other indications, such as sterility. | 35 | 0.09 | 2 | 23.12 | 3.44e-03 |
oxygen and reactive oxygen species metabolic process | The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). | 121 | 0.30 | 3 | 10.03 | 3.50e-03 |
response to virus | A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. | 124 | 0.31 | 3 | 9.79 | 3.75e-03 |
negative regulation of biological process | Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 1697 | 4.19 | 11 | 2.62 | 3.98e-03 |
negative regulation of MAPK activity | Any process that stops, prevents or reduces the frequency, rate or extent of MAP kinase activity. | 39 | 0.10 | 2 | 20.75 | 4.26e-03 |
negative regulation of transcription | Any process that stops, prevents or reduces the frequency, rate or extent of transcription. | 439 | 1.09 | 5 | 4.61 | 5.07e-03 |
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. | 478 | 1.18 | 5 | 4.23 | 7.19e-03 |
regulation of cell proliferation | Any process that modulates the frequency, rate or extent of cell proliferation. | 704 | 1.74 | 6 | 3.45 | 8.81e-03 |
antigen processing and presentation of peptide antigen via MHC class I | The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. | 60 | 0.15 | 2 | 13.48 | 9.83e-03 |