L2L Microarray Analysis Tool

steroid metabolic process

60.13

3.28e-17

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.

234

1.16

18

15.56

4.00e-16

lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

299

1.48

19

12.85

2.06e-15

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

106

0.52

13

24.81

1.09e-14

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

723

3.57

25

6.99

1.04e-13

lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

877

4.34

27

6.23

1.70e-13

alcohol metabolic process

The chemical reactions and pathways involving alcohols, any of a class of alkyl compounds containing a hydroxyl group.

408

2.02

17

8.43

4.90e-11

isoprenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

15

0.07

isoprenoid metabolic process

67.42

8.51e-09

biosynthetic process

The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones, as in growth and other biosynthetic processes.

1553

7.68

26

3.39

1.49e-07

The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.

27

0.13

37.46

2.18e-07

DNA replication

The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.

277

1.37

10

7.30

1.64e-06

sterol transport

The directed movement of sterols into, out of, within or between cells. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

16

0.08

3

37.93

6.45e-05

cholesterol transport

The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of, within or between cells.

16

0.08

3

37.93

6.45e-05

metabolic process

Processes that cause many of the chemical changes in living organisms, including anabolism and catabolism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.

9690

47.91

74

1.54

2.72e-04

RNA processing

Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

622

3.08

primary metabolic process

3.58

3.43e-04

Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

8941

44.20

68

1.54

5.16e-04

M phase

Progression through M phase, the part of the cell cycle comprising nuclear division and cytokinesis.

375

1.85

8

4.32

6.49e-04

cell cycle phase

A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events.

474

2.34

9

3.84

7.01e-04

DNA-dependent DNA replication

The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

140

0.69

cellular response to starvation

7.22

7.09e-04

cell cycle process

A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

1144

5.66

15

2.65

7.62e-04

cell division

The processes resulting in the physical partitioning and separation of a cell into daughter cells.

297

1.47

7

4.77

7.84e-04

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.

9

0.04

cellular response to extracellular stimulus

44.95

8.60e-04

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.

9

0.04

cellular response to nutrient levels

44.95

8.60e-04

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.

9

0.04

monocarboxylic acid metabolic process

44.95

8.60e-04

The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).

307

1.52

7

4.61

9.50e-04

ribosome biogenesis and assembly

The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis.

89

0.44

4

9.09

1.04e-03

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

1307

6.46

16

2.48

1.06e-03

response to starvation

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.

10

0.05

cellular metabolic process

40.45

1.07e-03

The chemical reactions and pathways by which individual cells transform chemical substances.

8889

43.95

66

1.50

1.10e-03

ribonucleoprotein complex biogenesis and assembly

The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together.

239

1.18

6

5.08

1.33e-03

DNA replication initiation

The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.

44

0.22

3

13.79

1.38e-03

terpenoid metabolic process

The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.

14

0.07

28.90

2.14e-03

germ cell migration

The orderly movement of a germ cell, a cell specialized to produce haploid gametes, through the embryo from its site of production to the place where the gonads will form.

14

0.07

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

28.90

2.14e-03

The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.

4320

21.36

36

1.69

2.31e-03

carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

679

3.36

10

2.98

2.40e-03

cell cycle checkpoint

A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage.

112

0.55

4

7.22

2.43e-03

organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.

681

3.37

10

2.97

2.46e-03

cholesterol absorption

Uptake of cholesterol into the blood by absorption from the small intestine.

15

0.07

26.97

2.46e-03

lipid digestion

The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.

15

0.07

cellular response to stimulus

26.97

2.46e-03

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.

15

0.07

M phase of mitotic cell cycle

26.97

2.46e-03

DNA metabolic process

The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

922

4.56

12

2.63

2.59e-03

mitosis

Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.

284

1.40

6

4.27

3.15e-03

Progression through M phase, the part of the mitotic cell cycle during which mitosis and cytokinesis take place.

290

1.43

6

4.18

3.48e-03

intestinal absorption

The processes by which nutrients are taken up from the contents of the intestine.

21

0.10

regulation of progression through cell cycle

19.26

4.82e-03

Any process that modulates the rate or extent of progression through the cell cycle.

875

4.33

2.54

4.92e-03

regulation of cell cycle

A cell cycle process that modulates the rate, extent or mode of the cell cycle.

880

4.35

2.53

5.13e-03

mitotic cell cycle

Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, in which a cell is duplicated without changing ploidy; comprises four successive phases called G1, S, G2, and M.

421

2.08

7

3.36

5.46e-03

autophagy

The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of nutrient limitation and remodeling the intracellular structure for cell differentiation.

23

0.11

regulation of cell differentiation

17.59

5.77e-03

Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.

233

1.15

fatty acid metabolic process

4.34

6.40e-03

The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

234

1.16

4.32

6.51e-03

DNA recombination

The processes by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

158

0.78

4

5.12

8.18e-03

digestive process

A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.

30

0.15