L2L Microarray Analysis Tool
Results for N06AA.profile.u50
| Results summary | View all lists in GO:CellComp | View all genes in N06AA.profile.u50 |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). | 922 | 2.28 | 12 | 5.27 | 4.84e-06 |
| ER to Golgi transport vesicle membrane | The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. | 15 | 0.04 | 3 | 80.91 | 6.72e-06 |
| COPII vesicle coat | One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state. | 15 | 0.04 | 3 | 80.91 | 6.72e-06 |
| ER to Golgi transport vesicle | A vesicle that mediates transport from the endoplasmic reticulum to the Golgi complex; bears a coat formed of the COPII coat complex proteins; such vesicles found associated with endoplasmic reticulum (ER) membranes at steady state, and are involved in ER to Golgi (anterograde) vesicle transport. | 19 | 0.05 | 3 | 63.87 | 1.42e-05 |
| transport vesicle membrane | The lipid bilayer surrounding a transport vesicle. | 47 | 0.12 | 3 | 25.82 | 2.26e-04 |
| Golgi-associated vesicle membrane | The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. | 49 | 0.12 | 3 | 24.77 | 2.56e-04 |
| endomembrane system | A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. | 657 | 1.62 | 8 | 4.93 | 2.80e-04 |
| Golgi-associated vesicle | Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. | 88 | 0.22 | 3 | 13.79 | 1.42e-03 |
| vesicle coat | A membrane coat found on a coated vesicle. | 88 | 0.22 | 3 | 13.79 | 1.42e-03 |
| transport vesicle | Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, and to destinations within or outside the cell. | 90 | 0.22 | 3 | 13.48 | 1.51e-03 |
| membrane coat | Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules. | 91 | 0.22 | 3 | 13.34 | 1.56e-03 |
| coated membrane | A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes. | 91 | 0.22 | 3 | 13.34 | 1.56e-03 |
| coated vesicle membrane | The lipid bilayer surrounding a coated vesicle. | 95 | 0.23 | 3 | 12.77 | 1.76e-03 |
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. | 124 | 0.31 | 3 | 9.79 | 3.75e-03 |
| cytoplasmic vesicle part | Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. | 132 | 0.33 | 3 | 9.19 | 4.46e-03 |
| vesicle membrane | The lipid bilayer surrounding any membrane-bounded vesicle in the cell. | 146 | 0.36 | 3 | 8.31 | 5.90e-03 |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. | 159 | 0.39 | 3 | 7.63 | 7.45e-03 |
| nuclear envelope-endoplasmic reticulum network | The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum. | 170 | 0.42 | 3 | 7.14 | 8.94e-03 |
| Golgi apparatus | A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. | 514 | 1.27 | 5 | 3.94 | 9.63e-03 |