Results summary | View all lists in GO:BiolProc | View all genes in R06AX.profile.ud50 |
List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
---|---|---|---|---|---|---|
acetyl-CoA metabolic process | The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. | 44 | 0.22 | 4 | 18.39 | 6.92e-05 |
tRNA metabolic process | The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. | 100 | 0.49 | 5 | 10.11 | 1.51e-04 |
alcohol metabolic process | The chemical reactions and pathways involving alcohols, any of a class of alkyl compounds containing a hydroxyl group. | 408 | 2.02 | 9 | 4.46 | 2.39e-04 |
negative regulation of I-kappaB kinase/NF-kappaB cascade | Any process that stops, prevents or reduces the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade. | 5 | 0.02 | 2 | 80.91 | 2.42e-04 |
isoprenoid metabolic process | The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. | 27 | 0.13 | 3 | 22.47 | 3.23e-04 |
steroid biosynthetic process | The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. | 99 | 0.49 | 4 | 8.17 | 1.55e-03 |
sterol biosynthetic process | The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 49 | 0.24 | 3 | 12.38 | 1.88e-03 |
tRNA aminoacylation for protein translation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis. | 56 | 0.28 | 3 | 10.84 | 2.75e-03 |
amino acid activation | The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. | 56 | 0.28 | 3 | 10.84 | 2.75e-03 |
tRNA aminoacylation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. | 56 | 0.28 | 3 | 10.84 | 2.75e-03 |
DNA replication | The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. | 277 | 1.37 | 6 | 4.38 | 2.79e-03 |
sterol metabolic process | The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. | 117 | 0.58 | 4 | 6.92 | 2.84e-03 |
apoptosis | A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. | 1078 | 5.33 | 13 | 2.44 | 3.36e-03 |
coenzyme metabolic process | The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. | 201 | 0.99 | 5 | 5.03 | 3.45e-03 |
programmed cell death | Cell death resulting from activation of endogenous cellular processes. | 1086 | 5.37 | 13 | 2.42 | 3.57e-03 |
cellular lipid metabolic process | The chemical reactions and pathways involving lipids, as carried out by individual cells. | 723 | 3.57 | 10 | 2.80 | 3.73e-03 |
cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate. | 2359 | 11.66 | 22 | 1.89 | 4.32e-03 |
cellular developmental process | A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. | 2359 | 11.66 | 22 | 1.89 | 4.32e-03 |
DNA-dependent DNA replication | The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. | 140 | 0.69 | 4 | 5.78 | 5.38e-03 |
cell death | The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. | 1152 | 5.70 | 13 | 2.28 | 5.76e-03 |
death | A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. | 1152 | 5.70 | 13 | 2.28 | 5.76e-03 |
steroid metabolic process | The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. | 234 | 1.16 | 5 | 4.32 | 6.51e-03 |
carboxylic acid metabolic process | The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). | 679 | 3.36 | 9 | 2.68 | 7.51e-03 |
organic acid metabolic process | The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. | 681 | 3.37 | 9 | 2.67 | 7.65e-03 |
cofactor metabolic process | The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. | 247 | 1.22 | 5 | 4.09 | 8.12e-03 |